scholarly journals Characterization of the A‐type potassium current in murine gastric antrum

2002 ◽  
Vol 544 (2) ◽  
pp. 417-428 ◽  
Author(s):  
Gregory C. Amberg ◽  
Salah A. Baker ◽  
Sang Don Koh ◽  
William J. Hatton ◽  
Keith J. Murray ◽  
...  
Keyword(s):  
Potassium Current ◽  
Gastric Antrum

Characterization of an E4031-Sensitive Potassium Current in Quiescent AT-1 Cells

1994 ◽  
Vol 5 (12) ◽  
pp. 1017-1030 ◽  
Author(s):  
YANING LIU ◽  
STEVEN M. TAFFET ◽  
JUSTUS M.B. ANUMONWO ◽  
MARIO DELMAR
Keyword(s):  
Potassium Current

Quisqualate and ACPD are agonists for a glutamate-activated current in identified Aplysia neurons

1993 ◽  
Vol 69 (1) ◽  
pp. 143-150 ◽  
Author(s):  
P. S. Katz ◽  
I. B. Levitan
Keyword(s):  
Glutamate Receptor ◽  
Potassium Current ◽  
Chloride Current ◽  
Current Response ◽  
Buccal Ganglion ◽  
Glutamate Agonists ◽  
Potassium Response ◽  
Ganglion Neurons ◽  
Higher Sensitivity

1. Glutamate is an important neurotransmitter in both vertebrates and invertebrates, yet the characterization of molluscan glutamate receptors and their relationships to vertebrate receptors is incomplete. This study uses two-electrode voltage clamp to characterize glutamate-evoked currents in cultured neurons from the marine gastropod mollusk Aplysia californica. 2. The identified buccal ganglion neurons, B1 and B2, display two pharmacologically distinct current responses to pressure-applied glutamate. One response is a desensitizing chloride current similar to that found in other large buccal ganglion neurons. The other is a nondesensitizing potassium current that is strongly outwardly rectifying. 3. The potassium current response has a higher sensitivity to glutamate than the chloride response. 4. Individual neurons, isolated in primary cell culture, exhibit different relative proportions of the two currents. 5. The glutamate agonists quisqualate and (1S,3R)-aminocyclopentane-1,3-dicarboxylic acid specifically evoke the potassium response but not the chloride response. The glutamate agonist (RS)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid does not evoke any appreciable response. Kainate and N-methyl-D-aspartate also have no effect on these cells. Another glutamate analogue, ibotenate, evokes the transient chloride current but not the potassium current. 6. These results indicate that the glutamate receptor mediating the outward potassium response does not conform in its pharmacological profile to any of the known vertebrate glutamate receptor types.

Characterization of the Rapidly Activating Delayed Rectifier Potassium Current, I Kr, in HL-1 Mouse Atrial Myocytes

2010 ◽  
Vol 235 (2) ◽  
pp. 73-87 ◽  
Author(s):  
Futoshi Toyoda ◽  
Wei-Guang Ding ◽  
Dimitar P. Zankov ◽  
Mariko Omatsu-Kanbe ◽  
Takahiro Isono ◽  
...  
Keyword(s):  
Potassium Current ◽  
Delayed Rectifier ◽  
Atrial Myocytes ◽  
Delayed Rectifier Potassium Current

Immunocytochemical characterization of monoclonal antibody A2B5 in the rat gastric antrum

1987 ◽  
Vol 22 (6) ◽  
pp. 685-689
Author(s):  
Takeshi Azuma ◽  
Keiichi Kawai ◽  
John H. Walsh
Keyword(s):  
Monoclonal Antibody ◽  
Gastric Antrum

scholarly journals Characterization of a hyperpolarization-activated time-dependent potassium current in canine cardiomyocytes from pulmonary vein myocardial sleeves and left atrium

2004 ◽  
Vol 557 (2) ◽  
pp. 583-597 ◽  
Author(s):  
Joachim R. Ehrlich ◽  
Tae-Joon Cha ◽  
Liming Zhang ◽  
Denis Chartier ◽  
Louis Villeneuve ◽  
...  
Keyword(s):  
Left Atrium ◽  
Pulmonary Vein ◽  
Potassium Current ◽  
Time Dependent
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