scholarly journals Extracellular fluid translocation in perfused rabbit atria: implication in control of atrial natriuretic peptide secretion.

1993 ◽  
Vol 468 (1) ◽  
pp. 591-607 ◽  
Author(s):  
K W Cho ◽  
S H Kim ◽  
Y H Hwang ◽  
K H Seul
1989 ◽  
Vol 7 (5) ◽  
pp. 371-375 ◽  
Author(s):  
Kyung Woo Cho ◽  
Kyung Hwan Seul ◽  
Suhn Hee Kim ◽  
Kyung Mee Seul ◽  
Hoon Ryu ◽  
...  

1990 ◽  
Vol 172 (2) ◽  
pp. 423-431 ◽  
Author(s):  
Kyung Woo Cho ◽  
Kyung Hwan Seul ◽  
Suhn Hee Kim ◽  
Gou Young Koh ◽  
Kyung Mee Seul ◽  
...  

1992 ◽  
Vol 263 (3) ◽  
pp. R647-R652 ◽  
Author(s):  
O. Vuolteenaho ◽  
P. Koistinen ◽  
V. Martikkala ◽  
T. Takala ◽  
J. Leppaluoto

To evaluate the role of atrial natriuretic peptide (ANP) in exercise-related cardiovascular and hormonal adjustments in hypobaric conditions, 14 young athletes performed a maximal ergometer test in a hypobaric chamber adjusted to simulate the altitudes of sea level and 3,000 m. Plasma immunoreactive ANP levels rose from 5.89 to 35.1 pmol/l at sea level and rose significantly less (P less than 0.05), from 5.36 to 22.3 pmol/l, at simulated 3,000 m. Plasma immunoreactive amino-terminal peptide of proANP (NT-proANP) levels increased to the same extent at sea level and at simulated 3,000 m (from 240 to 481 pmol/l and from 257 to 539 pmol/l, respectively). Plasma immunoreactive aldosterone increased significantly less at simulated 3,000 m (P less than 0.05), but the changes in plasma renin were similar in both conditions. Plasma immunoreactive endothelin-1 and serum erythropoietin levels remained unchanged. In conclusion, we found a blunted ANP response to maximal exercise of ANP in acute hypobaric exposure compared with that in normobaric conditions, but no significant difference in the NT-proANP responses between the two conditions. The divergence may be due to stimulation of the elimination mechanism of ANP.


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