scholarly journals Mechanical Control of Extracellular Space in Rabbit Atria: An Intimate Modulator of the Translocation of Extracellular Fluid and Released Atrial Natriuretic Peptide

2002 ◽  
Vol 87 (2) ◽  
pp. 185-194 ◽  
Author(s):  
Kyung Woo Cho ◽  
Sook Jeong Lee ◽  
Jin Fu Wen ◽  
Suhn Hee Kim ◽  
Kyung Hwan Seul ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Extracellular Space ◽  
Extracellular Fluid ◽  
Mechanical Control ◽  
Rabbit Atria ◽  
Atrial Natriuretic

scholarly journals Ethanol Extract ofLepidium apetalumSeed Elicits Contractile Response and Attenuates Atrial Natriuretic Peptide Secretion in Beating Rabbit Atria

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Seung Ju Kim ◽  
Hye Yoom Kim ◽  
Yun Jung Lee ◽  
Hao Zhen Cui ◽  
Ji Yeon Jang ◽  
...  
Keyword(s):  
Stroke Volume ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Pulse Pressure ◽  
Kinase Inhibitor ◽  
Ethanol Extract ◽  
Dependent Manner ◽  
Rabbit Atria ◽  
Volume Pulse ◽  
Atrial Natriuretic

The seeds ofLepidium apetalumWilldenow (called “Tinglizi” in China and “Jungryukza” in Korea) have been used to discharge phlegm and improve dropsy in Oriental medicine. The present study investigated the effects of ethanol extract of the seeds ofLepidium apetalum(ELA) on atrial dynamics and atrial natriuretic peptide (ANP) secretion in beating rabbit atria. ELA increased atrial stroke volume, pulse pressure, and cAMP efflux, concomitantly attenuating ANP secretion in a dose-dependent manner. ELA-induced increases in atrial stroke volume, pulse pressure, and cAMP levels and decrease in ANP secretion were not inhibited by pretreatment with staurosporine, a nonspecific protein kinase inhibitor, or diltiazem and verapamil, the L-type Ca2+channel blockers, respectively. Helveticoside, a well-known digitalis-like cardiac glycosidic constituent of ELA, also increased atrial dynamics, including stroke volume and pulse pressure, without changing cAMP efflux and ANP secretion, and the effects of helveticoside were not inhibited by pretreatment with staurosporine, diltiazem, and verapamil. These results suggest that the ELA-induced positive inotropic activity in beating rabbit atria might, at least partly, be due to the digitalis-like activity of helveticoside rather than an increase in cAMP efflux.

Characteristics of distension-induced release of immunoreactive atrial natriuretic peptide in isolated perfused rabbit atria

1988 ◽  
Vol 22 (4) ◽  
pp. 333-345 ◽  
Author(s):  
Kyung Woo Cho ◽  
Kyung Hwan Seul ◽  
Hoon Ryu ◽  
Suhn Hee Kim ◽  
Gou Young Koh
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Rabbit Atria ◽  
Atrial Natriuretic

Ursolic acid increases the secretion of atrial natriuretic peptide in isolated perfused beating rabbit atria

2011 ◽  
Vol 653 (1-3) ◽  
pp. 63-69 ◽  
Author(s):  
Hao Zhen Cui ◽  
Jin Fu Wen ◽  
Hye Ran Choi ◽  
Xiang Li ◽  
Kyung Woo Cho ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Ursolic Acid ◽  
Rabbit Atria ◽  
Atrial Natriuretic

Reduction volume dependence of immunoreactive atrial natriuretic peptide secretion in isolated perfused rabbit atria

1989 ◽  
Vol 7 (5) ◽  
pp. 371-375 ◽  
Author(s):  
Kyung Woo Cho ◽  
Kyung Hwan Seul ◽  
Suhn Hee Kim ◽  
Kyung Mee Seul ◽  
Hoon Ryu ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Volume Dependence ◽  
Peptide Secretion ◽  
Rabbit Atria ◽  
Atrial Natriuretic
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