scholarly journals Ion activities and potassium uptake mechanisms of glial cells in guinea-pig olfactory cortex slices.

1987 ◽  
Vol 382 (1) ◽  
pp. 159-174 ◽  
Author(s):  
K Ballanyi ◽  
P Grafe ◽  
G ten Bruggencate
Keyword(s):  
Guinea Pig ◽  
Glial Cells ◽  
Olfactory Cortex ◽  
Potassium Uptake ◽  
Ion Activities ◽  
Cortex Slices ◽  
Uptake Mechanisms

scholarly journals Cellular mechanisms of potassium homeostasis in the mammalian nervous system

1987 ◽  
Vol 65 (5) ◽  
pp. 1038-1042 ◽  
Author(s):  
P. Grafe ◽  
K. Ballanyi
Keyword(s):  
Guinea Pig ◽  
Glial Cells ◽  
Sympathetic Ganglia ◽  
Olfactory Cortex ◽  
Lateral Olfactory Tract ◽  
Cellular Mechanisms ◽  
Potassium Homeostasis ◽  
Ion Sensitive Microelectrodes ◽  
Sympathetic Neurones ◽  
Intracellular Activities

Double-barrelled ion-sensitive microelectrodes were used to measure changes in the intracellular activities of K+, Na+, and Cl− (aKi, aNai, aCli) in neurones of rat sympathetic ganglia and in glial cells of slices from guinea-pig olfactory cortex. In sympathetic neurones, carbachol and γ-aminobutyric acid (GABA) produced a reversible decrease of aKi. The decrease of aKi during carbachol was accompanied by a rise of aNai, whereas in the presence of GABA decreases of aKi and aCli were seen. The reuptake of K+ released during the action of carbachol was completely blocked by ouabain, whereas furosemide inhibited the aKi recovery after the action of GABA. In glial cells, in contrast to the observations in the sympathetic neurones, aKi and aCli increased, whereas aNai decreased when neuronal activity was enhanced by repetitive stimulation of the lateral olfactory tract. It was found that barium ions and ouabain strongly reduced the activity-related rise of intraglial aKi in slices of guinea-pig olfactory cortex. These data show that mammalian neurones as well as glial cells possess several K+ uptake mechanisms that contribute to potassium homeostasis. Ouabain, furosemide, and Ba2+ are useful pharmacological tools to separate these mechanisms.

Effects of coenzymes Q2 and Q10 on the field potential of guinea pig olfactory cortex slices maintained in hypoxia

1990 ◽  
Vol 110 (1-2) ◽  
pp. 40-45
Author(s):  
Takanori Fujii ◽  
Michiko Hayashi ◽  
Ken'ichi Toita ◽  
Yoshihide Yamasaki
Keyword(s):  
Guinea Pig ◽  
Field Potential ◽  
Olfactory Cortex ◽  
Cortex Slices
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