scholarly journals Induction of action potentials in cultured slow muscle fibres of the frog.

1980 ◽  
Vol 299 (1) ◽  
pp. 197-202 ◽  
Author(s):  
S G Cull-Candy ◽  
R Miledi ◽  
O D Uchitel
Keyword(s):  
Action Potentials ◽  
Slow Muscle ◽  
Muscle Fibres ◽  
Slow Muscle Fibres

scholarly journals The different intracellular action potentials of fast and slow muscle fibres

1985 ◽  
Vol 60 (6) ◽  
pp. 539-547 ◽  
Author(s):  
Willemien Wallinga-De Jonge ◽  
Frans L.H Gielen ◽  
Peter Wirtz ◽  
Paul De Jong ◽  
Jan Broenink
Keyword(s):  
Action Potentials ◽  
Slow Muscle ◽  
Muscle Fibres ◽  
Fast And Slow Muscle ◽  
Slow Muscle Fibres ◽  
Intracellular Action

Inhibition by a actinomycin D of the denervation-induced action potential in frog slow muscle fibres

1973 ◽  
Vol 184 (1074) ◽  
pp. 91-95 ◽  
Keyword(s):  
Sciatic Nerve ◽  
Action Potential ◽  
Action Potentials ◽  
Rna Synthesis ◽  
Actinomycin D ◽  
Slow Muscle ◽  
Muscle Fibres ◽  
Na Channels ◽  
Potential Mechanism ◽  
Slow Muscle Fibres

Pyriformis muscles of the frog were denervated by section of the sciatic nerve. About three weeks later all slow muscle fibres examined had become capable of generating action potentials. However, the action potential mechanism failed to develop if actinomycin D was injected early after the operation. It is suggested that RNA synthesis is required for the formation of ‘Na channels’ in the membrane of denervated slow muscle fibres.

Action potentials induced in slow muscle fibres by partial denervation

Nature ◽  
1975 ◽  
Vol 253 (5487) ◽  
pp. 122-123 ◽  
Author(s):  
G. SCHALOW ◽  
H. SCHMIDT
Keyword(s):  
Action Potentials ◽  
Slow Muscle ◽  
Muscle Fibres ◽  
Partial Denervation ◽  
Slow Muscle Fibres

Induction of action potentials in frog slow muscle fibres paralysed by α-bungarotoxin

1981 ◽  
Vol 213 (1191) ◽  
pp. 243-248 ◽  
Keyword(s):  
Action Potential ◽  
Action Potentials ◽  
Acetylcholine Receptors ◽  
Intramuscular Injection ◽  
Slow Muscle ◽  
Muscle Fibres ◽  
Nerve Terminals ◽  
Potential Mechanism ◽  
Slow Muscle Fibres

Slow muscle fibres in the frog are normally incapable of generating action potentials. However, several days after an intramuscular injection of α-bungarotoxin, they acquire the ability to generate action potentials. It appears that α-bungarotoxin induces the action potential mechanism in slow fibres because it blocks acetylcholine receptors, and thus interferes with the action of non-quantal acetylcholine leaking from nerve terminals, or because the toxin has some other, as yet undefined, action on nerve or muscle.

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