scholarly journals Factors concerned in the regulation of sweat production in man

1955 ◽  
Vol 127 (2) ◽  
pp. 280-296 ◽  
Author(s):  
D. McK. Kerslake
Keyword(s):  
2009 ◽  
Vol 35 (6) ◽  
pp. 588-592 ◽  
Author(s):  
F. Aydin ◽  
G. S. Pancar ◽  
N. Senturk ◽  
Y. Bek ◽  
E. P. Yuksel ◽  
...  

2020 ◽  
Author(s):  
Julia Brunmair ◽  
Laura Niederstaetter ◽  
Benjamin Neuditschko ◽  
Andrea Bileck ◽  
Astrid Slany ◽  
...  

AbstractMetabolic biomonitoring in humans is typically based on the sampling of blood, plasma or urine. Although established in the clinical routine, these sampling procedures are often associated with a variety of compliance issues and are impractical for performing time-course studies. The analysis of the minute amounts of sweat sampled from the fingertip enables a solution to this challenge. Sweat sampling from the fingertip is non-invasive and robust and can be accomplished repeatedly by untrained personnel. This matrix represents a rich source for metabolomic phenotyping, which is exemplified by the detection of roughly 50’000 features per sample. Moreover, the determined limits of detection demonstrate that the ingestion of 200 μg of a xenobiotic may be sufficient for its detection in sweat from the fingertip. The feasibility of short interval sampling of sweat from the fingertips was confirmed in three time-course studies after coffee consumption or ingestion of a caffeine capsule, successfully monitoring all known caffeine metabolites. Fluctuations in the rate of sweat production were accounted for by mathematical modelling to reveal individual rates of caffeine uptake, metabolism and clearance. Biomonitoring using sweat from the fingertip has far reaching implications for personalised medical diagnostics and biomarker discovery.


2019 ◽  
Vol 90 (9-10) ◽  
pp. 1130-1140
Author(s):  
Courtney Oswald ◽  
Emiel DenHartog

Moisture management is important for the human comfort of clothing, especially while perspiring. Ideally, the fabric chosen for a garment enables moisture to migrate away from the skin surface, facilitating the liquid to be evaporated into the surrounding environment, which causes a cooling sensation for the wearer. This process is influenced by factors such as fiber type, fabric construction, and fabric treatments, all of which impact the resulting wicking and moisture management properties of the fabric. This research explored the heat loss associated with combined water absorption, wicking, and evaporative cooling during wetting of fabrics. A dynamic sweating guarded hot plate was used to measure transitional heat loss as water was introduced at a steady rate over a 65-minute testing period. The results on a cotton and polyester blend fabric as well as a wool fabric indicated that the liquid water absorption and transport processes significantly influence heat loss properties during this transition. However, the results also show novel aspects in the efficiency of cooling associated with the wicking of sweat and different stages of wetting of fabrics leading to different cooling power. Furthermore, this method raises questions as to whether current sweating guarded hot plate technologies are an appropriate representation of human sweat production or that the scalability of sweat production per unit area is limited. This developed testing method can be successful in quantifying the differences in transitional heat loss and will enable testing of fabrics for comfort in changing conditions.


1979 ◽  
Vol 92 (2) ◽  
pp. 511-512 ◽  
Author(s):  
A. K. Rai ◽  
B. S. Mehta ◽  
M. Singh

Although sheep combat thermal stress mainly by panting, a sizeable amount (40%) of total evaporative heat loss, is from sources other than panting (Hales & Brown, 1974). The frequency of sporadic discharge of sweat glands increases with increase in ambient temperature and is accompanied by a decline in respiration rate (Bligh, 1961). The wool coat can reduce evaporative cooling but sweating may have cooling value in sheep breeds with open fleeces (Rai, Singh & More, 1978). In sheep, the number and size of the sweat glands (Waites & Voglmayr, 1962) and the quantum of sweat production in a particular time period (Ghoshal et al. 1977) varies in different body regions. In view of the possible significance of surface evaporative cooling, thermal sweating in different body regions of sheep was investigated.


1988 ◽  
Vol 65 (2) ◽  
pp. 811-814 ◽  
Author(s):  
M. J. Buono ◽  
N. T. Sjoholm

The purpose of this study was to determine the in vivo secretory activity of sweat glands from sedentary and trained subjects. Peripheral sweat production was determined using pilocarpine iontophoresis in 40 volunteers (10 sedentary men, 10 endurance-trained men, 10 sedentary women, 10 endurance-trained women). Peripheral sweat rate was significantly (P less than 0.05) greater in trained men [6.9 +/- 0.6 (SE) g.m2.min-1] and women (6.1 +/- 0.7) compared with sedentary men (3.1 +/- 0.5) and women (2.5 +/- 0.4). Furthermore, peripheral sweat rate was significantly correlated (r = 0.73) with maximal O2 uptake. The above two findings would suggest that physical training improves the secretory activity of the human sweat gland. Such a result supports previous findings that have suggested that the potentiation in sweating seen after training is achieved via a peripheral mechanism. In addition, several gender-related differences were found in the sudorific response of men and women. Specifically, women have a significantly greater sweat gland density, whereas men have a greater sweat production per gland.


2008 ◽  
Vol 8 (1) ◽  
Author(s):  
Mark Schaefer ◽  
Mavi Schellenberg ◽  
Uta Merle ◽  
Karl Heinz Weiss ◽  
Wolfgang Stremmel

1984 ◽  
Vol 104 (6) ◽  
pp. 904-905 ◽  
Author(s):  
William A. Gahl ◽  
Van S. Hubbard ◽  
Sheldon Orloff
Keyword(s):  

Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3379
Author(s):  
Laura Patterson Rosa ◽  
Martha F. Mallicote ◽  
Robert J. MacKay ◽  
Samantha A. Brooks

Macrolide drugs are the treatment of choice for Rhodococcus equi infections, despite severe side-effects temporary anhidrosis as a. To better understand the molecular biology leading to macrolide induced anhidrosis, we performed skin biopsies and Quantitative Intradermal Terbutaline Sweat Tests (QITSTs) in six healthy pony-cross foals for three different timepoints during erythromycin administration—pre-treatment (baseline), during anhidrosis and post-recovery. RNA sequencing of biopsies followed by differential gene expression analysis compared both pre and post normal sweating timepoints to the erythromycin induced anhidrosis episode. After Bonferroni correction for multiple testing, 132 gene transcripts were significantly differentially expressed during the anhidrotic timepoint. Gene ontology analysis of the full differentially expressed gene set identified over-represented biological functions for ubiquitination and ion-channel function, both biologically relevant to sweat production. These same mechanisms were previously implicated in heritable equine idiopathic anhidrosis and sweat gland function and their involvement in macrolide-induced temporary anhidrosis warrants further investigation.


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