scholarly journals Endothelial tubes: another window into lymphatic function

2017 ◽  
Vol 595 (24) ◽  
pp. 7267-7268
Author(s):  
Kim A. Dora ◽  
Dirk F. van Helden
Keyword(s):  
Lymphatic Function ◽  
Endothelial Tubes

Impact of cardiopulmonary bypass and cardioplegic arrest on myocardial lymphatic function

1995 ◽  
Vol 268 (1) ◽  
pp. H178-H183 ◽  
Author(s):  
U. Mehlhorn ◽  
K. L. Davis ◽  
E. J. Burke ◽  
D. Adams ◽  
G. A. Laine ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Myocardial Edema ◽  
Dry Weight ◽  
Myocardial Contraction ◽  
Left Ventricular ◽  
Lymph Flow ◽  
Cardioplegic Arrest ◽  
Lymphatic Function

Cardioplegic arrest (CPA) is associated with interstitial myocardial edema, which has been shown to impair myocardial function. The accumulation of interstitial myocardial edema may be enhanced by impaired myocardial lymph flow. The purpose of this study was to investigate the effects of CPA on myocardial lymphatic function. In nine anesthetized dogs, we cannulated a prenodal cardiac lymphatic and measured myocardial lymph flow rate (QL), myocardial lymph driving pressure (PL), and myocardial lymph hyaluronan (Hya) concentration. We determined left ventricular function using pressure-volume curves derived by sonomicrometry and micromanometry. The dogs were placed on cardiopulmonary bypass (CPB) (28 degrees C) and subjected to 60 min of hypothermic, crystalloid CPA. With the onset of asystole both QL and PL decreased significantly from 70.7 +/- 31.8 (SD) to 3.3 +/- 4.0 microliters/min and from 19.9 +/- 8.0 to 10.4 +/- 1.8 mmHg, respectively (P < 0.01). Following return of sinus rhythm after separation from CPB, QL and PL increased significantly to 135.4 +/- 28.0 microliters/min and 27.3 +/- 7.5 mmHg, respectively (P < 0.01). Post-CPA myocardial edema was demonstrated by gravimetric wet-to-dry weight determination of 3.67 +/- 0.20 (normal 2.90 +/- 0.20, P < 0.001) and was associated with significantly decreased left ventricular function. Myocardial Hya turnover rate was 1.3 +/- 1.0% per day under baseline conditions and increased significantly to 2.7 +/- 0.9% per day post-CPA (P < 0.01). We conclude that organized myocardial contraction is the major determinant of myocardial lymph flow. Myocardial lymph flow impairment during CPA may contribute to post-CPA myocardial edema and left ventricular dysfunction.

Global abnormalities in lymphatic function following systemic therapy in patients with breast cancer

2015 ◽  
Vol 102 (5) ◽  
pp. 534-540 ◽  
Author(s):  
S. K. Bains ◽  
A. M. Peters ◽  
C. Zammit ◽  
N. Ryan ◽  
J. Ballinger ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systemic Therapy ◽  
Lymphatic Function

Donor-Site Lymphatic Function after Microvascular Lymph Node Transfer

2012 ◽  
Vol 130 (6) ◽  
pp. 1246-1253 ◽  
Author(s):  
Tiina P. Viitanen ◽  
Maija T. Mäki ◽  
Marko P. Seppänen ◽  
Erkki A. Suominen ◽  
Anne M. Saaristo
Keyword(s):  
Lymph Node ◽  
Donor Site ◽  
Lymphatic Function ◽  
Lymph Node Transfer

Advances in understanding and examining lymphatic function

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
William Ambler ◽  
Laura Santambrogio ◽  
Theresa T. Lu
Keyword(s):  
Lymphatic Function

scholarly journals Cytokines are systemic effectors of lymphatic function in acute inflammation

Cytokine ◽  
2013 ◽  
Vol 64 (1) ◽  
pp. 362-369 ◽  
Author(s):  
Melissa B. Aldrich ◽  
Eva M. Sevick-Muraca
Keyword(s):  
Acute Inflammation ◽  
Lymphatic Function

scholarly journals Direct evidence of lymphatic function improvement after advanced pneumatic compression device treatment of lymphedema

2010 ◽  
Vol 1 (1) ◽  
pp. 114 ◽  
Author(s):  
Kristen E. Adams ◽  
John C. Rasmussen ◽  
Chinmay Darne ◽  
I-Chih Tan ◽  
Melissa B. Aldrich ◽  
...  
Keyword(s):  
Direct Evidence ◽  
Lymphatic Function ◽  
Compression Device ◽  
Pneumatic Compression Device
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