scholarly journals Twenty-five years of CLC chloride transport proteins

2015 ◽  
Vol 593 (18) ◽  
pp. 4083-4084 ◽  
Author(s):  
Peying Fong
PLoS ONE ◽  
2011 ◽  
Vol 6 (3) ◽  
pp. e17647 ◽  
Author(s):  
Emily McMains ◽  
Vijai Krishnan ◽  
Sujitha Prasad ◽  
Evanna Gleason

2006 ◽  
Vol 553 (1-3) ◽  
pp. 205-208 ◽  
Author(s):  
Marta Valero ◽  
Désirée Pereboom ◽  
Ricardo P. Garay ◽  
José Octavio Alda

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Monica Sala-Rabanal ◽  
Zeynep Yurtsever ◽  
Kayla N. Berry ◽  
Tom J. Brett

Chloride transport proteins play critical roles in inflammatory airway diseases, contributing to the detrimental aspects of mucus overproduction, mucus secretion, and airway constriction. However, they also play crucial roles in contributing to the innate immune properties of mucus and mucociliary clearance. In this review, we focus on the emerging novel roles for a chloride channel regulator (CLCA1), a calcium-activated chloride channel (TMEM16A), and two chloride exchangers (SLC26A4/pendrin and SLC26A9) in chronic inflammatory airway diseases.


2010 ◽  
Vol 69 (12) ◽  
pp. 1228-1246 ◽  
Author(s):  
Sarah N.R. Pressey ◽  
Kieran J. O'Donnell ◽  
Tobias Stauber ◽  
Jens C. Fuhrmann ◽  
Jaana Tyynelä ◽  
...  

Author(s):  
G. Zampighi ◽  
M. Kreman

The plasma membranes of most animal cells contain transport proteins which function to provide passageways for the transported species across essentially impermeable lipid bilayers. The channel is a passive transport system which allows the movement of ions and low molecular weight molecules along their concentration gradients. The pump is an active transport system and can translocate cations against their natural concentration gradients. The actions and interplay of these two kinds of transport proteins control crucial cell functions such as active transport, excitability and cell communication. In this paper, we will describe and compare several features of the molecular organization of pumps and channels. As an example of an active transport system, we will discuss the structure of the sodium and potassium ion-activated triphosphatase [(Na+ +K+)-ATPase] and as an example of a passive transport system, the communicating channel of gap junctions and lens junctions.


Sign in / Sign up

Export Citation Format

Share Document