Role of hydrogen sulfide (H 2 S) in ventilatory responses to hypercapnia in the medullary raphe of adult rats

2021 ◽  
Author(s):  
João Paulo Jacob Sabino ◽  
Lucas Vaz de Castro Oliveira ◽  
Renato Nery Soriano ◽  
Marcelo Kwiatkoski ◽  
Luiz G. S. Branco ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Adult Rats ◽  
Ventilatory Responses ◽  
Medullary Raphe

scholarly journals Role of hydrogen sulfide (H2S) on the ventilatory responses to hypercapnia

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Glauber S F Silva ◽  
Marcelo Kwiatkoski ◽  
Humberto Giusti ◽  
Mogens L Glass ◽  
Luiz G S Branco
Keyword(s):  
Hydrogen Sulfide ◽  
Ventilatory Responses

The Role of Reactive Oxygen Species, Kinases, Hydrogen Sulfide, and Nitric Oxide in the Regulation of Autophagy and Their Impact on Ischemia and Reperfusion Injury in the Heart

2020 ◽  
Vol 16 ◽  
Author(s):  
Andrey Krylatov ◽  
Leonid Maslov ◽  
Sergey Y. Tsibulnikov ◽  
Nikita Voronkov ◽  
Alla Boshchenko ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Reactive Oxygen Species ◽  
Hydrogen Sulfide ◽  
Ischemia Reperfusion ◽  
Reactive Oxygen ◽  
Ischemia And Reperfusion ◽  
Oxygen Species ◽  
Ischemia And Reperfusion Injury ◽  
Adaptive Process

: There is considerable evidence in the heart that autophagy in cardiomyocytes is activated by hypoxia/reoxygenation (H/R) or in hearts by ischemia/reperfusion (I/R). Depending upon the experimental model and duration of ischemia, increases in autophagy in this setting maybe beneficial (cardioprotective) or deleterious (exacerbate I/R injury). Aside from the conundrum as to whether or not autophagy is an adaptive process, it is clearly regulated by a number of diverse molecules including reactive oxygen species (ROS), various kinases, hydrogen sulfide (H2S) and nitric oxide (NO). The purpose this review is to address briefly the controversy regarding the role of autophagy in this setting and to examine a variety of disparate molecules that are involved in its regulation.

Taurine treatment reverses protein malnutrition-induced endothelial dysfunction of the pancreatic vasculature: the role of hydrogen sulfide

Metabolism ◽  
2021 ◽  
pp. 154701
Author(s):  
Daniele M. Guizoni ◽  
Israelle N. Freitas ◽  
Jamaira A. Victorio ◽  
Isabela R. Possebom ◽  
Thiago R. Araujo ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Endothelial Dysfunction ◽  
Protein Malnutrition ◽  
Taurine Treatment

Development of sensitivity to cAMP-inducing hormones in the rat stomach

1984 ◽  
Vol 247 (3) ◽  
pp. G231-G239
Author(s):  
C. Gespach ◽  
Y. Cherel ◽  
G. Rosselin
Keyword(s):  
Biological Activities ◽  
Physiological Role ◽  
H2 Receptor Antagonist ◽  
Adult Rats ◽  
Gastric Glands ◽  
Camp Generation ◽  
Final Maturation ◽  
Noncompetitive Inhibitor ◽  
Regulatory Properties

Development of cAMP responses to secretin, pancreatic glucagon, and histamine was measured in gastric glands of fetal (day 20), postnatal (days 1-30), and adult rats (day 65). cAMP stimulation by these hormones was already detected on day 20 of gestation. cAMP generation showed biphasic variations during the 1st days of life and at the onset of weaning (day 20). Anticipated weaning at day 14 triggered precocious maturation (efficacies) of the cAMP-generating systems sensitive to secretin, glucagon, and histamine without changing the potencies of the hormones. During development, the general characteristics (potency and pharmacological or regulatory properties) of the receptor-cAMP systems studied were comparable with those evidenced in adult rats. At days 5, 20, and 65, vasoactive intestinal peptide and the peptide having N-terminal histidine and C-terminal isoleucine amide (PHI) were about 100 times less potent than secretin (EC50 = 1.5 X 10(-9) M secretin). The histamine action could be blocked by the competitive H2-receptor antagonist cimetidine (70-100% inhibition) as well as by the noncompetitive inhibitor somatostatin (37-62% inhibition). The data indicate that these regulatory hormones (secretin, glucagon(s), histamine, and somatostatin) might have a direct effect on gastric glands and may modulate their biological activities (metabolism, differentiation, proliferation, and exocrine and endocrine secretions) from the neonatal period in rats. The important physiological role of weaning on the final maturation of the cAMP-generating systems in rat gastric glands is underlined.

scholarly journals Sex- and age-based differences in the effect of central serotonin on arterial blood pressure regulation

2020 ◽  
Vol 129 (6) ◽  
pp. 1310-1323
Author(s):  
Jennifer L. Magnusson ◽  
Craig A. Emter ◽  
Kevin J. Cummings
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Nrem Sleep ◽  
Blood Pressure Regulation ◽  
Pressure Regulation ◽  
Adult Rats ◽  
Arterial Blood ◽  
Serotonin Neurons ◽  
Older Males

The role of serotonin in arterial blood pressure (ABP) regulation across states of vigilance is unknown. We hypothesized that adult rats devoid of CNS serotonin (TPH2−/−) have low ABP in wakefulness and NREM sleep, when serotonin neurons are active. However, TPH2−/− rats experience higher ABP than TPH2+/+ rats in wakefulness and REM only, a phenotype present only in older males and not females. CNS serotonin may be critical for preventing high ABP in males with aging.

Role of hydrogen sulfide in cerebrovascular alteration during aging

2019 ◽  
Vol 42 (5) ◽  
pp. 446-454 ◽  
Author(s):  
Juyeon Mun ◽  
Hye-Min Kang ◽  
Junyang Jung ◽  
Chan Park
Keyword(s):  
Hydrogen Sulfide

NaHS inhibits NF-κB signal against inflammation and oxidative stress in post-infectious irritable bowel syndrome

RSC Advances ◽  
2016 ◽  
Vol 6 (69) ◽  
pp. 64208-64214 ◽  
Author(s):  
Shenglan Yang ◽  
Danfang Deng ◽  
Yingying Luo ◽  
Yanran Wu ◽  
Rui Zhu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Irritable Bowel Syndrome ◽  
Hydrogen Sulfide ◽  
Murine Model ◽  
Irritable Bowel ◽  
And Oxidative Stress ◽  
Post Infectious

In this study, the alleviating role of hydrogen sulfide (H2S) was investigated in a Post-Infectious Irritable Bowel Syndrome (PI-IBS) murine model and Caco-2 cells.

scholarly journals Role of molybdenum in corrosion of iron-based alloys in contact with hydrogen sulfide containing solution

2016 ◽  
Vol 68 (6) ◽  
pp. 595-603 ◽  
Author(s):  
G. Genchev ◽  
C. Bosch ◽  
E. Wanzenberg ◽  
A. Erbe
Keyword(s):  
Hydrogen Sulfide ◽  
Iron Based ◽  
Corrosion Of Iron

scholarly journals Role of the medullary raphé in thermoregulatory vasomotor control in rats

2002 ◽  
Vol 540 (2) ◽  
pp. 657-664 ◽  
Author(s):  
Mutsumi Tanaka ◽  
Kei Nagashima ◽  
Robin M. McAllen ◽  
Kazuyuki Kanosue
Keyword(s):  
Vasomotor Control ◽  
Medullary Raphe
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