Effectiveness of broad‐spectrum antiseptics in production of disinfected maggots of Lucilia sericata for use in wound debridement therapy

2021 ◽  
Author(s):  
Meriem Taleb
Keyword(s):  
Broad Spectrum ◽  
Lucilia Sericata ◽  
Wound Debridement

scholarly journals Endotoxin testing of a wound debridement device containing medicinal Lucilia sericata larvae

2017 ◽  
Vol 25 (3) ◽  
pp. 498-501
Author(s):  
Samantha F. Pickles ◽  
David I. Pritchard
Keyword(s):  
Lucilia Sericata ◽  
Wound Debridement

scholarly journals Gene expression in Lucilia sericata (Diptera: Calliphoridae) larvae exposed to Pseudomonas aeruginosa and Acinetobacter baumanii identifies shared and microbe-specific induction of immune genes

2021 ◽  
Author(s):  
Claire H McKenna ◽  
Danial Asgari ◽  
Tawni C Crippen ◽  
Le Zheng ◽  
Ronald A Sherman ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pseudomonas Aeruginosa ◽  
Pathogenic Bacteria ◽  
Molecular Level ◽  
Lucilia Sericata ◽  
Acinetobacter Baumanii ◽  
Wound Debridement ◽  
Immune Genes ◽  
Specific Induction ◽  
Deficiency Gene

Antibiotic resistance is a continuing challenge in medicine. There are various strategies for expanding antibiotic therapeutic repertoires, including the use of blow flies. Their larvae exhibit strong antibiotic and antibiofilm properties that alter microbiome communities. One species, Lucilia sericata, is used to treat problematic wounds due to its debridement capabilities and its excretions and secretions that kill some pathogenic bacteria. There is much to be learned about how L. sericata interacts with microbiomes at the molecular level. To address this deficiency, gene expression was assessed after feeding exposure (1 hour or 4 hours) to two clinically problematic pathogens: Pseudomonas aeruginosa and Acinetobacter baumanii. The results identified immunity related genes that were differentially expressed when exposed to these pathogens, as well as non-immune genes possibly involved in gut responses to bacterial infection. There was a greater response to P. aeruginosa that increased over time, while few genes responded to A. baumanii exposure and expression was not time-dependent. The response to feeding on pathogens indicates a few common responses and features distinct to each pathogen, which is useful in improving wound debridement therapy and helps develop biomimetic alternatives.

Wound debridement potential of glycosidases of the wound-healing maggot, Lucilia sericata

2012 ◽  
Vol 26 (3) ◽  
pp. 291-299 ◽  
Author(s):  
G. TELFORD ◽  
A. P. BROWN ◽  
A. RICH ◽  
J. S. C. ENGLISH ◽  
D. I. PRITCHARD
Keyword(s):  
Wound Healing ◽  
Lucilia Sericata ◽  
Wound Debridement

scholarly journals Effectiveness of Chronic Wound Debridement with the Use of Larvae of Lucilia Sericata

2019 ◽  
Vol 8 (11) ◽  
pp. 1845 ◽  
Author(s):  
Dariusz Bazaliński ◽  
Maria Kózka ◽  
Magdalena Karnas ◽  
Paweł Więch
Keyword(s):  
Chronic Wound ◽  
Scientific Evidence ◽  
Bacterial Load ◽  
Cost Effective ◽  
Tissue Growth ◽  
Lucilia Sericata ◽  
Wound Debridement ◽  
Cost Effective Method ◽  
Phaenicia Sericata ◽  
Maggot Therapy

The process of successful wound healing depends on effective debridement and infection control. One method of wound debridement, known since antiquity, is based on the use of fly larvae. Solid scientific evidence proves that maggot debridement therapy (MDT), like surgical intervention, can be effectively and safely used to remove necrotic tissue. Based on a review of the related literature, this study was designed to assess the effectiveness of chronic wound cleansing with the use of larvae of Lucilia sericata (Phaenicia sericata). Maggot therapy, applied in wound debridement and treatment, is a safe and effective method. Its benefits are associated with debridement, disinfection and faster tissue growth. MDT may reduce the duration of antibiotic therapy and the need for hospitalization, or it may decrease the number of outpatient visits required. It is a relatively cost-effective method, and, in addition to financial gains, it may reduce the frequency of inpatient treatment. In the literature, an increasing amount of scientific evidence confirms that such treatment can effectively reduce the biofilm and bacterial load in a wound.

A Jonah-like chymotrypsin from the therapeutic maggot Lucilia sericata plays a role in wound debridement and coagulation

2016 ◽  
Vol 70 ◽  
pp. 138-147 ◽  
Author(s):  
Anne-Kathrin Pöppel ◽  
Mareike Kahl ◽  
Andre Baumann ◽  
Jochen Wiesner ◽  
Anke Gökçen ◽  
...  
Keyword(s):  
Lucilia Sericata ◽  
Wound Debridement

A Strengths-Based Approach to Autism: Neurodiversity and Partnering With the Autism Community

2017 ◽  
Vol 2 (1) ◽  
pp. 56-68 ◽  
Author(s):  
Amy L. Donaldson ◽  
Karen Krejcha ◽  
Andy McMillin
Keyword(s):  
Broad Spectrum ◽  
First Language ◽  
Family Members ◽  
Community Identity ◽  
Speech Language Pathologists

The autism community represents a broad spectrum of individuals, including those experiencing autism, their parents and/or caregivers, friends and family members, professionals serving these individuals, and other allies and advocates. Beliefs, experiences, and values across the community can be quite varied. As such, it is important for the professionals serving the autism community to be well-informed about current discussions occurring within the community related to neurodiversity, a strengths-based approach to partnering with autism community, identity-first language, and concepts such as presumed competence. Given the frequency with which speech-language pathologists (SLPs) serve the autism community, the aim of this article is to introduce and briefly discuss these topics.

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