Quality of erythrocyte concentrates derived from lipemic whole blood donations

2018 ◽  
Vol 13 (4) ◽  
pp. 440-445
Author(s):  
Lara A.E. de Laleijne-Liefting ◽  
Johan W. Lagerberg ◽  
Dirk de Korte
Keyword(s):  
Whole Blood ◽  
Blood Donations ◽  
Erythrocyte Concentrates

Quality of frozen transfusable plasma prepared from whole blood donations in Canada: An update

2013 ◽  
Vol 49 (3) ◽  
pp. 440-446 ◽  
Author(s):  
William P. Sheffield ◽  
Varsha Bhakta ◽  
Kimberley Talbot ◽  
Edward L.G. Pryzdial ◽  
Craig Jenkins
Keyword(s):  
Whole Blood ◽  
Blood Donations

Conversion to the buffy coat method and quality of frozen plasma derived from whole blood donations in Canada

Transfusion ◽  
2010 ◽  
Vol 50 (5) ◽  
pp. 1043-1049 ◽  
Author(s):  
William P. Sheffield ◽  
Varsha Bhakta ◽  
Craig Jenkins ◽  
Dana V. Devine
Keyword(s):  
Whole Blood ◽  
Buffy Coat ◽  
Blood Donations ◽  
Frozen Plasma

scholarly journals Whole blood chromium concentration is very rarely elevated independently of whole blood cobalt

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Olli Lainiala ◽  
Mari Karsikas ◽  
Aleksi Reito ◽  
Antti Eskelinen
Keyword(s):  
Whole Blood ◽  
Cost Savings ◽  
Chromium Concentration ◽  
Continuous Variables ◽  
Metal Debris ◽  
Screening Guidelines ◽  
Metal On Metal ◽  
Hip Replacements

AbstractDue to the risk of adverse reactions to metal debris resulting from increased wear of the arthroplasty more than one million metal-on-metal (MoM) hip replacements worldwide are in active follow-up. Follow-up usually includes measurement of both whole blood cobalt (Co) and chromium (Cr) concentrations. Our experience is that Cr is seldom independently elevated. We wanted to ascertain whether blood Cr measurements could be omitted from follow-up protocols without lowering the quality of follow-up. We identified 8438 whole blood Co and Cr measurements performed without or prior to revision surgery. When the cut-off levels 5 µg/L and 7 µg/L were used, Cr was independently elevated in only 0.5% (95% confidence interval, CI, 0.3 to 0.6) and 0.2% (CI 0.1 to 0.3) of the measurements. The models with continuous variables showed that the higher the blood metal concentrations are the lower the percentage of measurements with Cr higher than Co. Our results suggest that whole blood Cr is very rarely independently elevated and therefore the authorities should consider omitting Cr measurements from their screening guidelines of MoM hip replacements. We believe this change in practice would simplify follow-up and lead to cost savings without decreasing the quality of follow-up.

scholarly journals In vitro characteristics and in vivo platelet quality of whole blood treated with riboflavin and UVA / UVB light and stored for 24 hours at room temperature

Transfusion ◽  
2021 ◽  
Vol 61 (S1) ◽  
Author(s):  
Turid Helen Felli Lunde ◽  
Lindsay Hartson ◽  
Shawn Lawrence Bailey ◽  
Tor Audun Hervig
Keyword(s):  
Whole Blood ◽  
Room Temperature

scholarly journals Detection of Babesia RNA and DNA in whole blood samples from US blood donations

Transfusion ◽  
2021 ◽  
Author(s):  
Jean Stanley ◽  
Susan L. Stramer ◽  
Yasuko Erickson ◽  
Julie Cruz ◽  
Jed Gorlin ◽  
...  
Keyword(s):  
Whole Blood ◽  
Blood Donations ◽  
Blood Samples ◽  
Whole Blood Samples ◽  
Rna And Dna

Multivariate analysis of determinants of bacterial contamination of whole-blood donations

Vox Sanguinis ◽  
2002 ◽  
Vol 82 (2) ◽  
pp. 55-60 ◽  
Author(s):  
P. Perez ◽  
C. Bruneau ◽  
M. Chassaigne ◽  
L. R. Salmi ◽  
L. Noel ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Whole Blood ◽  
Bacterial Contamination ◽  
Blood Donations

In vitro quality of amotosalen‐ UVA pathogen‐inactivated mini‐pool plasma prepared from whole blood stored overnight

Vox Sanguinis ◽  
2018 ◽  
Vol 113 (7) ◽  
pp. 622-631 ◽  
Author(s):  
Catherine Ravanat ◽  
Arnaud Dupuis ◽  
Nadine Marpaux ◽  
Christian Naegelen ◽  
Guillaume Mourey ◽  
...  
Keyword(s):  
Whole Blood

scholarly journals Erythrocyte Concentrates Recovered from Under-Collected Whole Blood: Experimental and Clinical Results

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0117928 ◽  
Author(s):  
Wen-Biao Liang ◽  
Ming-Hua Guo ◽  
En-Yong Fan ◽  
Jing-Jing Zhang ◽  
Min-Hui Wu ◽  
...  
Keyword(s):  
Whole Blood ◽  
Clinical Results ◽  
Erythrocyte Concentrates

scholarly journals Quality Control of Serum and Plasma by Quantification of (4E,14Z)-Sphingadienine-C18-1-Phosphate Uncovers Common Preanalytical Errors During Handling of Whole Blood

2018 ◽  
Vol 64 (5) ◽  
pp. 810-819 ◽  
Author(s):  
Xinyu Liu ◽  
Miriam Hoene ◽  
Peiyuan Yin ◽  
Louise Fritsche ◽  
Peter Plomgaard ◽  
...  
Keyword(s):  
Whole Blood ◽  
Plasma Samples ◽  
Blood Samples ◽  
Disease States ◽  
Long Term Storage ◽  
Reliable Assessment ◽  
Therapeutic Decisions ◽  
Life Threatening ◽  
Research Findings

Abstract BACKGROUND Nonadherence to standard operating procedures (SOPs) during handling and processing of whole blood is one of the most frequent causes affecting the quality of serum and plasma. Yet, the quality of blood samples is of the utmost importance for reliable, conclusive research findings, valid diagnostics, and appropriate therapeutic decisions. METHODS UHPLC-MS-driven nontargeted metabolomics was applied to identify biomarkers that reflected time to processing of blood samples, and a targeted UHPLC-MS analysis was used to quantify and validate these biomarkers. RESULTS We found that (4E,14Z)-sphingadienine-C18-1-phosphate (S1P-d18:2) was suitable for the reliable assessment of the pronounced changes in the quality of serum and plasma caused by errors in the phase between collection and centrifugation of whole blood samples. We rigorously validated S1P-d18:2, which included the use of practicality tests on >1400 randomly selected serum and plasma samples that were originally collected during single- and multicenter trials and then stored in 11 biobanks in 3 countries. Neither life-threatening disease states nor strenuous metabolic challenges (i.e., high-intensity exercise) affected the concentration of S1P-d18:2. Cutoff values for sample assessment were defined (plasma, ≤0.085 μg/mL; serum, ≤0.154 μg/mL). CONCLUSIONS Unbiased valid monitoring to check for adherence to SOP-dictated time for processing to plasma or serum and/or time to storage of whole blood at 4 °C is now feasible. This novel quality assessment step could enable scientists to uncover common preanalytical errors, allowing for identification of serum and plasma samples that should be excluded from certain investigations. It should also allow control of samples before long-term storage in biobanks.

Comparison of Different Methods Used in the Preparation of Leucocyte-Free Whole Blood and Erythrocyte Concentrates

Vox Sanguinis ◽  
1970 ◽  
Vol 19 (1) ◽  
pp. 57-63
Author(s):  
M. Langfelder ◽  
M. Jakschitz ◽  
A. Jánossy
Keyword(s):  
Whole Blood ◽  
Erythrocyte Concentrates
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