Evaluation of tissue hemoglobin saturation (StO 2 ) using near-infrared spectroscopy during hypoxemia and hyperoxemia in Beagle dogs

2016 ◽  
Vol 43 (1) ◽  
pp. 18-26 ◽  
Author(s):  
Noah D Pavlisko ◽  
Maria Killos ◽  
Natalia Henao-Guerrero ◽  
Carolina H Riccó ◽  
Stephen Werre
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Beagle Dogs ◽  
Hemoglobin Saturation ◽  
Tissue Hemoglobin

Cerebral desaturation during exercise reversed by O2 supplementation

1999 ◽  
Vol 277 (3) ◽  
pp. H1045-H1052 ◽  
Author(s):  
H. B. Nielsen ◽  
R. Boushel ◽  
P. Madsen ◽  
N. H. Secher
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Cerebral Oxygenation ◽  
Vastus Lateralis ◽  
Work Capacity ◽  
Vastus Lateralis Muscle ◽  
Double Blind ◽  
Hemoglobin Saturation ◽  
Concentration Changes

The combined effects of hyperventilation and arterial desaturation on cerebral oxygenation ([Formula: see text]) were determined using near-infrared spectroscopy. Eleven competitive oarsmen were evaluated during a 6-min maximal ergometer row. The study was randomized in a double-blind fashion with an inspired O2 fraction of 0.21 or 0.30 in a crossover design. During exercise with an inspired O2 fraction of 0.21, the arterial CO2 pressure (35 ± 1 mmHg; mean ± SE) and O2 pressure (77 ± 2 mmHg) as well as the hemoglobin saturation (91.9 ± 0.7%) were reduced ( P < 0.05).[Formula: see text] was reduced from 80 ± 2 to 63 ± 2% ( P < 0.05), and the near-infrared spectroscopy-determined concentration changes in deoxy- (ΔHb) and oxyhemoglobin (ΔHbO2) of the vastus lateralis muscle increased 22 ± 3 μM and decreased 14 ± 3 μM, respectively ( P < 0.05). Increasing the inspired O2fraction to 0.30 did not affect ventilation (174 ± 4 l/min), but arterial CO2 pressure (37 ± 2 mmHg), O2 pressure (165 ± 5 mmHg), and hemoglobin O2saturation (99 ± 0.1%) increased ( P < 0.05).[Formula: see text] remained close to the resting level during exercise (79 ± 2 vs. 81 ± 2%), and although the muscle ΔHb (18 ± 2 μM) and ΔHbO2 (−12 ± 3 μM) were similar to those established without O2 supplementation, work capacity increased from 389 ± 11 to 413 ± 10 W ( P < 0.05). These results indicate that an elevated inspiratory O2fraction increases exercise performance related to maintained cerebral oxygenation rather than to an effect on the working muscles.

Noninvasive determination of hemoglobin saturation in dogs by derivative near-infrared spectroscopy

1989 ◽  
Vol 256 (5) ◽  
pp. H1493-H1499 ◽  
Author(s):  
M. Ferrari ◽  
D. A. Wilson ◽  
D. F. Hanley ◽  
J. F. Hartmann ◽  
M. C. Rogers ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Linear Regression Analysis ◽  
Sagittal Sinus ◽  
Hemoglobin Saturation ◽  
Wide Range ◽  
Anesthetized Dogs ◽  
Predicted Values

An in vivo method utilizing derivative near-infrared spectroscopy was developed to noninvasively determine cerebral venous hemoglobin O2 saturation (SVO2). The method was tested on eight pentobarbital-anesthetized dogs ventilated with differing inspired O2 mixtures to force changes in SVO2 over a wide range. Spectral data obtained by transilluminating the tissues surrounding the superior sagittal sinus (SS) were transformed into first derivative units for correlation with SVO2 data measured from the SS. Linear regression analysis was applied to data obtained from five dogs and used to build a three-wavelength algorithm for predicting brain SVO2. In three dogs, SVO2 was varied to test this equation ability to predict SVO2. The standard deviation of differences between measured SVO2 and SVO2 predicted from 31 separate spectra was 3.2%. These predicted values, when regressed against the sampled SVO2, yielded an r value of 0.97. The results demonstrate that during hypoxic hypoxia (HH) it is possible to noninvasively quantify SVO2 with the use of infrared spectroscopy.

Quantitative detection of hemoglobin saturation in the liver with near-infrared spectroscopy

Hepatology ◽  
1993 ◽  
Vol 18 (4) ◽  
pp. 926-936 ◽  
Author(s):  
Toshiyuki Kitai ◽  
Akira Tanaka ◽  
Atsuo Tokuka ◽  
Koichi Tanaka ◽  
Yoshio Yamaoka ◽  
...  
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Quantitative Detection ◽  
Hemoglobin Saturation

Near-infrared spectroscopy (NIRS) – a promising brain imaging method in Psychiatry?

2008 ◽  
Vol 39 (01) ◽  
Author(s):  
AJ Fallgatter ◽  
AC Ehlis ◽  
MM Richter ◽  
M Schecklmann ◽  
MM Plichta
Keyword(s):  
Infrared Spectroscopy ◽  
Brain Imaging ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Imaging Method
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