scholarly journals Current state of transfusion in traumatic brain injury and associated coagulopathy

Transfusion ◽  
2019 ◽  
Vol 59 (S2) ◽  
pp. 1522-1528 ◽  
Author(s):  
Moritz Stolla ◽  
Fangyi Zhang ◽  
Michael R. Meyer ◽  
Jianning Zhang ◽  
Jing‐Fei Dong
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Current State

scholarly journals Depression following traumatic brain injury: a comprehensive overview

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Marc Fakhoury ◽  
Zaynab Shakkour ◽  
Firas Kobeissy ◽  
Nada Lawand
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Health Concern ◽  
First Year ◽  
Comprehensive Overview ◽  
Symptoms Of Depression ◽  
Current State ◽  
Post Traumatic ◽  
Brain Changes

Abstract Traumatic brain injury (TBI) represents a major health concern affecting the neuropsychological health; TBI is accompanied by drastic long-term adverse complications that can influence many aspects of the life of affected individuals. A substantial number of studies have shown that mood disorders, particularly depression, are the most frequent complications encountered in individuals with TBI. Post-traumatic depression (P-TD) is present in approximately 30% of individuals with TBI, with the majority of individuals experiencing symptoms of depression during the first year following head injury. To date, the mechanisms of P-TD are far from being fully understood, and effective treatments that completely halt this condition are still lacking. The aim of this review is to outline the current state of knowledge on the prevalence and risk factors of P-TD, to discuss the accompanying brain changes at the anatomical, molecular and functional levels, and to discuss current approaches used for the treatment of P-TD.

scholarly journals The current state of biomarkers of mild traumatic brain injury

JCI Insight ◽  
2018 ◽  
Vol 3 (1) ◽  
Author(s):  
Han Jun Kim ◽  
Jack W. Tsao ◽  
Ansley Grimes Stanfill
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Current State

Current State and Prospects of Development of Blood-based Biomarkers for Mild Traumatic Brain Injury

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Hyun Haeng Lee ◽  
Woo Hyung Lee ◽  
Han Gil Seo ◽  
Dohyun Han ◽  
Youngsoo Kim ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Current State

Apathy After Traumatic Brain Injury: An Overview of the Current State of Play

2011 ◽  
Vol 12 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Amanda T. Lane-Brown ◽  
Robyn L. Tate
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Current Knowledge ◽  
Reliability And Validity ◽  
Current Evidence ◽  
Negative Consequences ◽  
Current State ◽  
Clinical Presentations ◽  
Current Knowledge Base ◽  
Methods Of Treatment

AbstractApathy is a decrease in behavioural, cognitive and emotional components of goal-directed behaviour. Clinically, it is characterised by diminished initiation, reduced concern, and decreased activity. Apathy is a common occurrence following traumatic brain injury (TBI), occurring in around 60% of people. Consequences are widespread, negatively impacting independence, social integration, rehabilitation outcome, vocational outcome, coping and caregiver burden. The current knowledge base on apathy following TBI is presented, with implications for clinical practice. This includes a review of clinical presentations, neuroanatomical and neurochemical substrates associated with apathy, and differential diagnoses. Instruments to measure apathy are presented, highlighting those with demonstrated reliability and validity for the TBI population. Current evidence for pharmacological and non-pharmacological methods of treatment is described, with a model for non-pharmacological interventions provided and discussion of challenges faced by clinicians when treating the patient with apathy. In the TBI arena, greater understanding of apathy and methods of treatment is pivotal given the frequency of occurrence and widespread negative consequences.

scholarly journals The Current State of Traumatic Brain Injury Biomarker Measurement Methods

Biosensors ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 319
Author(s):  
Alyse D. Krausz ◽  
Frederick K. Korley ◽  
Mark A. Burns
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Point Of Care ◽  
Future Research ◽  
Protein Biomarkers ◽  
Research Directions ◽  
Current State ◽  
Diagnosis And Classification ◽  
Future Research Directions ◽  
Measurement Devices

Traumatic brain injury (TBI) is associated with high rates of morbidity and mortality partially due to the limited tools available for diagnosis and classification. Measuring panels of protein biomarkers released into the bloodstream after injury has been proposed to diagnose TBI, inform treatment decisions, and monitor the progression of the injury. Being able to measure these protein biomarkers at the point-of-care would enable assessment of TBIs from the point-of-injury to the patient’s hospital bedside. In this review, we provide a detailed discussion of devices reported in the academic literature and available on the market that have been designed to measure TBI protein biomarkers in various biofluids and contexts. We also assess the challenges associated with TBI biomarker measurement devices and suggest future research directions to encourage translation of these devices to clinical use.

scholarly journals The Acute Inflammatory Response in Trauma /Hemorrhage and Traumatic Brain Injury: Current State and Emerging Prospects

2008 ◽  
Vol 4 (3) ◽  
pp. 97-103 ◽  
Author(s):  
R. Namas ◽  
A. Ghuma ◽  
L. Hermus ◽  
R. Zamora ◽  
D.O. Okonkwo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Inflammatory Response ◽  
Acute Inflammatory Response ◽  
Current State

Serving Individuals with Traumatic Brain Injury

1994 ◽  
Vol 15 (5) ◽  
pp. 319-325 ◽  
Author(s):  
ANTONIS KATSIYANNIS ◽  
GREG CONDERMAN
Keyword(s):  
Traumatic Brain Injury ◽  
Special Education ◽  
Brain Injury ◽  
Technical Assistance ◽  
Eligibility Criteria ◽  
Directors Of Special Education ◽  
Current State ◽  
State Directors ◽  
And Training

THIS PAPER REPORTS FINDINGS FROM A SURVEY OF 48 STATE DIRECTORS OF SPECIAL EDUCATION. THE SURVEY COLLECTED INFORMATION ON CURRENT STATE PRACTICES IN PROVIDING SERVICES TO INDIVIDUALS WITH TRAUMATIC BRAIN INJURY, WITH AN EMPHASIS ON TECHNICAL ASSISTANCE, TRAINING, AND ELIGIBILITY CRITERIA. VARIATIONS AMONG STATES IN THE AVAILABILITY AND NATURE OF ELIGIBILITY CRITERIA, DEFINITIONS, TECHNICAL ASSISTANCE, AND TRAINING WERE FOUND.

scholarly journals The Acute Inflammatory Response in Trauma / Hemorrhage and Traumatic Brain Injury: Current State and Emerging Prospects

2009 ◽  
Vol 4 (3) ◽  
pp. 136-148 ◽  
Author(s):  
R Namas ◽  
A Ghuma ◽  
L Hermus ◽  
R Zamora ◽  
DO Okonkwo ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Inflammatory Response ◽  
Acute Inflammatory Response ◽  
Current State
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