Bilirubin levels and phototherapy use before and after neonatal red blood cell transfusions

Transfusion ◽  
2016 ◽  
Vol 56 (11) ◽  
pp. 2727-2731
Author(s):  
Patrick D. Carroll ◽  
Robert D. Christensen ◽  
Vickie L. Baer ◽  
Mark J. Sheffield ◽  
Erick Gerday ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Before And After ◽  
Red Blood Cell Transfusions

Implementation of a transfusion bundle reduces inappropriate red blood cell transfusions in intensive care - a before and after study

2016 ◽  
Vol 26 (6) ◽  
pp. 432-439 ◽  
Author(s):  
M. Borgert ◽  
J. Binnekade ◽  
F. Paulus ◽  
M. Vroom ◽  
A. Vlaar ◽  
...  
Keyword(s):  
Intensive Care ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Before And After ◽  
Red Blood Cell Transfusions ◽  
Before And After Study

scholarly journals Cardiorespiratory monitoring of red blood cell transfusions in preterm infants

2021 ◽  
Author(s):  
Jarinda A. Poppe ◽  
Tanja van Essen ◽  
Willem van Weteringen ◽  
Sten P. Willemsen ◽  
Irwin K. M. Reiss ◽  
...  
Keyword(s):  
Blood Cell ◽  
Preterm Infants ◽  
Red Blood Cell ◽  
Hemoglobin Concentration ◽  
Repeated Measurements ◽  
Before And After ◽  
Red Blood Cell Transfusions ◽  
Monitor Data ◽  
Preterm Newborns ◽  
Rbc Transfusion

AbstractClinical improvement after red blood cell (RBC) transfusions in preterm infants remains debated. This study aims to investigate the effect of RBC transfusion on the occurrence of desaturations and hypoxia, and other cardiorespiratory outcomes in preterm infants. In this longitudinal observational study, prospectively stored cardiorespiratory parameters of preterm infants who received at least one RBC transfusion between July 2016 and June 2017 were retrospectively analyzed. Sixty infants with 112 RBC transfusions, median GA of 26.7 weeks, were included. The number of desaturations and area < 80% SpO2 limit, as a measure of the hypoxic burden, were calculated in 24 h before and after RBC transfusion. A mixed effects model was used to account for repeated measurements. Overall, the mean (SE) number of desaturations per hour decreased from 3.28 (0.55) to 2.25 (0.38; p < 0.001), and area < 80% SpO2 limit decreased from 0.14 (0.04) to 0.08 (0.02) %/s (p = 0.02). These outcomes were stratified for the number of desaturations in 24 h prior to RBC transfusion. The largest effect was observed in the group with the highest mean number of desaturations (≥ 6) prior to RBC transfusion, with a decrease from 7.50 (0.66) to 4.26 (0.38) (p < 0.001) in the number of desaturations and 0.46 (0.13) to 0.20 (0.06) in the area < 80% SpO2. Perfusion index increased significantly after RBC transfusion (p < 0.001). No other significant effects of RBC transfusion on cardiorespiratory data were observed.Conclusions: RBC transfusions in preterm newborns could help decrease the incidence of desaturations and the area < 80% SpO2 as a measure of the hypoxic burden. The higher the number of desaturations prior to the RBC transfusion, the larger the effect observed. What is Known:•Red blood cell transfusions potentially prevent hypoxia in anemic preterm infants by increasing the circulatory hemoglobin concentration and improving tissue oxygenation.•There is not a predefined hemoglobin concentration cut-off for the occurrence of symptomatic anemia in preterm infants. What is New:•Oxygen desaturations and hypoxia in anemic preterm infants can be improved by RBC transfusions, especially if more desaturations have occurred before transfusion.•Cardiorespiratory monitor data may help identify infants who will benefit most from red blood cell transfusions.

Different threshold levels for red blood cell transfusions in patients with haematological malignancy

2009 ◽  
Author(s):  
Rachel Pawson ◽  
Susan Brunskill ◽  
Michael F Murphy ◽  
Carolyn Doree ◽  
Chris Hyde ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Haematological Malignancy ◽  
Threshold Levels ◽  
Red Blood Cell Transfusions
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