Implementation of a transfusion bundle reduces inappropriate red blood cell transfusions in intensive care - a before and after study

2016 ◽  
Vol 26 (6) ◽  
pp. 432-439 ◽  
Author(s):  
M. Borgert ◽  
J. Binnekade ◽  
F. Paulus ◽  
M. Vroom ◽  
A. Vlaar ◽  
...  
Keyword(s):  
Intensive Care ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Before And After ◽  
Red Blood Cell Transfusions ◽  
Before And After Study

Red blood cell transfusions—are we narrowing the evidence-practice gap? An observational study in 5 Israeli intensive care units

2011 ◽  
Vol 26 (1) ◽  
pp. 106.e1-106.e6 ◽  
Author(s):  
Jonathan Cohen ◽  
Ilya Kagan ◽  
Remos Hershcovici ◽  
Sylvianne Bursztein-De Myttenaere ◽  
Nicola Makhoul ◽  
...  
Keyword(s):  
Intensive Care ◽  
Observational Study ◽  
Blood Cell ◽  
Intensive Care Units ◽  
Red Blood Cell ◽  
Red Blood Cell Transfusions ◽  
Practice Gap

scholarly journals The use of a blood conservation device to reduce red blood cell transfusion requirements: a before and after study

Critical Care ◽  
2010 ◽  
Vol 14 (1) ◽  
pp. R7 ◽  
Author(s):  
Amartya Mukhopadhyay ◽  
Hwee S Yip ◽  
Dimple Prabhuswamy ◽  
Yiong H Chan ◽  
Jason Phua ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Red Blood Cell Transfusion ◽  
Blood Conservation ◽  
Transfusion Requirements ◽  
Before And After ◽  
Before And After Study

scholarly journals Cardiorespiratory monitoring of red blood cell transfusions in preterm infants

2021 ◽  
Author(s):  
Jarinda A. Poppe ◽  
Tanja van Essen ◽  
Willem van Weteringen ◽  
Sten P. Willemsen ◽  
Irwin K. M. Reiss ◽  
...  
Keyword(s):  
Blood Cell ◽  
Preterm Infants ◽  
Red Blood Cell ◽  
Hemoglobin Concentration ◽  
Repeated Measurements ◽  
Before And After ◽  
Red Blood Cell Transfusions ◽  
Monitor Data ◽  
Preterm Newborns ◽  
Rbc Transfusion

AbstractClinical improvement after red blood cell (RBC) transfusions in preterm infants remains debated. This study aims to investigate the effect of RBC transfusion on the occurrence of desaturations and hypoxia, and other cardiorespiratory outcomes in preterm infants. In this longitudinal observational study, prospectively stored cardiorespiratory parameters of preterm infants who received at least one RBC transfusion between July 2016 and June 2017 were retrospectively analyzed. Sixty infants with 112 RBC transfusions, median GA of 26.7 weeks, were included. The number of desaturations and area < 80% SpO2 limit, as a measure of the hypoxic burden, were calculated in 24 h before and after RBC transfusion. A mixed effects model was used to account for repeated measurements. Overall, the mean (SE) number of desaturations per hour decreased from 3.28 (0.55) to 2.25 (0.38; p < 0.001), and area < 80% SpO2 limit decreased from 0.14 (0.04) to 0.08 (0.02) %/s (p = 0.02). These outcomes were stratified for the number of desaturations in 24 h prior to RBC transfusion. The largest effect was observed in the group with the highest mean number of desaturations (≥ 6) prior to RBC transfusion, with a decrease from 7.50 (0.66) to 4.26 (0.38) (p < 0.001) in the number of desaturations and 0.46 (0.13) to 0.20 (0.06) in the area < 80% SpO2. Perfusion index increased significantly after RBC transfusion (p < 0.001). No other significant effects of RBC transfusion on cardiorespiratory data were observed.Conclusions: RBC transfusions in preterm newborns could help decrease the incidence of desaturations and the area < 80% SpO2 as a measure of the hypoxic burden. The higher the number of desaturations prior to the RBC transfusion, the larger the effect observed. What is Known:•Red blood cell transfusions potentially prevent hypoxia in anemic preterm infants by increasing the circulatory hemoglobin concentration and improving tissue oxygenation.•There is not a predefined hemoglobin concentration cut-off for the occurrence of symptomatic anemia in preterm infants. What is New:•Oxygen desaturations and hypoxia in anemic preterm infants can be improved by RBC transfusions, especially if more desaturations have occurred before transfusion.•Cardiorespiratory monitor data may help identify infants who will benefit most from red blood cell transfusions.

scholarly journals Red blood cell transfusion practice in a Pediatric Intensive Care Unit

2011 ◽  
Vol 9 (2) ◽  
pp. 135-139
Author(s):  
Cibele Mendes ◽  
Dafne Cardoso Bourguignon da Silva ◽  
Rodrigo Genaro Arduini ◽  
Eduardo Juan Troster
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Blood Cell ◽  
Pediatric Intensive Care Unit ◽  
Red Blood Cell ◽  
Pediatric Intensive Care ◽  
Hemoglobin Concentration ◽  
Multiple Organ ◽  
Therapeutic Procedure ◽  
Red Blood Cell Transfusions

Objectives: To describe a population of children that received red blood cell transfusions. Methods: A retrospective observational study carried out at the Pediatric Intensive Care Unit of the Instituto da Criança of Hospital das Clínicas of Faculdade de Medicina of Universidade de São Paulo in 2004, with children that received red blood cell transfusions. Results: Transfusion of red blood cells was performed in 50% of the patients hospitalized. Median age was 18 months, and the primary motive for admission was respiratory insufficiency (35%). Underlying disease was present in 84% of the cases and multiple organ and system dysfunction in 46.2%. The median value of pretransfusion hemoglobin concentration was 7.8 g/dL. Transfused patients were undergoing some form of therapeutic procedure in 82% of the cases. Conclusions: Red blood cell transfusions are performed at all ages. Hemoglobin concentration and hematocrit rate are the primary data used to indicate these transfusions. The values of arterial serum lactate and SvO2 were seldom used. Most patients transfused were submitted to some form of therapeutic procedure, and in many cases, transfusions were carried out in patients with multiple organ and system dysfunctions.

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