Safety measures to prevent hepatitis E virus transmission by blood transfusion

Transfusion ◽  
2014 ◽  
Vol 54 (8) ◽  
pp. 2134-2135 ◽  
Author(s):  
Syria Laperche ◽  
Jacques Izopet ◽  
Jean-Jacques Lefrère
Keyword(s):  
Blood Transfusion ◽  
Hepatitis E Virus ◽  
Virus Transmission ◽  
Hepatitis E ◽  
Safety Measures

Blood transfusion is unlikely to be a source for hepatitis E virus transmission in India

2020 ◽  
Vol 39 (2) ◽  
pp. 161-164 ◽  
Author(s):  
Vijay J. Halkurike ◽  
Amit Goel ◽  
Harshita Katiyar ◽  
Surendra Kumar Agarwal ◽  
Shantanu Pande ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Hepatitis E Virus ◽  
Virus Transmission ◽  
Hepatitis E

Seroprevalence of the hepatitis E virus antibodies among blood donors in the Qassim region, Saudi Arabia

2021 ◽  
Author(s):  
Bader Y Alhatlani ◽  
Waleed A Aljabr ◽  
Mohammed S Almarzouqi ◽  
Sami M Alhatlani ◽  
Rayan N Alzunaydi ◽  
...  
Keyword(s):  
Public Health ◽  
Saudi Arabia ◽  
Blood Transfusion ◽  
Hepatitis E Virus ◽  
Blood Donors ◽  
Indirect Elisa ◽  
Hepatitis E ◽  
Public Health Issue ◽  
Serum Samples ◽  
Major Public Health Issue

Aim: Hepatitis E virus (HEV) transmission through blood transfusion is a major public health issue worldwide. We aimed to determine the seroprevalence of HEV in blood donors in the Qassim region of Saudi Arabia. Materials & methods: Serum samples (n = 1078) were collected from volunteer blood donors and tested for the presence of anti-HEV IgG and IgM by indirect ELISA. Results: The seroprevalence of anti-HEV IgG among the blood donors was 5.7% overall. Anti-HEV IgG and IgM seropositivity were significantly higher in non-Saudi donors than in Saudi donors (22.1 vs 3 and 7.8 vs 0.2% for anti-HEV IgG and IgM, respectively). Conclusion: The seroprevalence of HEV among blood donors in the Qassim region was lower than previous estimates for other regions of the country and neighboring countries.

scholarly journals Blood-borne Hepatitis E Virus Transmission: A Relevant Risk for Immunosuppressed Patients

2016 ◽  
Vol 63 (4) ◽  
pp. 569-570 ◽  
Author(s):  
Sven Pischke ◽  
Jens Hiller ◽  
Marc Lütgehetmann ◽  
Susanne Polywka ◽  
Meike Rybczynski ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Virus Transmission ◽  
Hepatitis E ◽  
Immunosuppressed Patients

scholarly journals Seroprevalence of the hepatitis E virus among blood donors in the Qassim Region, Saudi Arabia

2020 ◽  
Author(s):  
Bader Alhatlani ◽  
Waleed Aljabr ◽  
Mohammed Almarzouqi ◽  
Sami Alhatlani ◽  
Rayan Alzunaydi ◽  
...  
Keyword(s):  
Public Health ◽  
Saudi Arabia ◽  
Blood Transfusion ◽  
Hepatitis E Virus ◽  
Blood Donors ◽  
Geographical Area ◽  
Hepatitis E ◽  
Public Health Issue ◽  
Serum Samples ◽  
Major Public Health Issue

Abstract Objectives The aim of this study was to evaluate the seroprevalence of hepatitis E virus (HEV), a major public health issue worldwide with the potential for transmission via blood transfusion, in blood donors in the Qassim Region, Saudi Arabia. Serum samples (n = 1,078) were collected from volunteer blood donors from January to April 2019 and tested for the presence of anti-HEV IgG and IgM by indirect enzyme-linked immunosorbent assays. Results Overall, the seroprevalence of anti-HEV IgG and IgM among blood donors was 5.7% and 1.3%, respectively. Additionally, the seropositive rates of anti-HEV IgG and IgM were significantly higher in non-Saudi donors (22.1% and 7.8%) than in Saudi donors (3% and 0.2%). The seroprevalence of anti-HEV IgG increased with age; however, there was no correlation between gender and anti-HEV IgG and/or IgM. The seroprevalence of HEV among blood donors in the Qassim Region was lower than previous estimates for other regions of the country. Further studies covering a wider geographical area are needed to validate and expand the findings and to determine the importance of HEV screening in the region.

scholarly journals Low Hepatitis E Virus Prevalence Among Blood Donor in Dali in China

2020 ◽  
Author(s):  
Ping Fu ◽  
Baochai Lin ◽  
Bingting Wu ◽  
Ling Ke ◽  
Tianfu Yang ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Ethnic Minority ◽  
Odds Ratio ◽  
Hepatitis E Virus ◽  
Blood Donors ◽  
Hepatitis E ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Samples ◽  
Iga Antibodies ◽  
Positive Rate

Abstract BACKGROUND: Hepatitis E virus (HEV) is a nonenveloped RNA virus causing Hepatitis E worldwide. An increasing transfusion transmission cases of HEV infections from asymptomatic blood donors which causing serious illnesses in immunosuppressed recipients have been reported in the past few years. China is one of the highly prevalent regions of HEV, it is important to evaluate the risk of HEV transmission from blood transfusion. METHODS: A total of 1864 serum samples from blood donors and demographic characteristics were randomly collected from Feb to Mar 2018 in Dali city. Anti-HEV IgG, IgM and IgA antibodies and HEV antigen were examined by enzyme-linked immunosorbent assay (ELISA). HEV RNA was detected by real-time PCR. Multivariable logistic regression modelling was used to examine risk factors associated with HEV prevalence.RESULTS: Overall, the positive rate of anti-HEV IgG, IgM, and IgA antibodies was 13.36% (249/1864), 1.13%(21/1864), and 1.82%(34/1864), respectively. However, none of the 1864 serum samples was detected as HEV antigen-positive nor HEV RNA positive. The positive rate of anti-HEV IgG antibody is high as 28.57% (2/7) in the donors with isolated elevated alanine aminotransferase (ALT). Females (16.69%) had a significantly higher HEV seroprevalence than males (13.04%) (odds ratio [OR]: 1.34 [95% CI, 1.02-1.75]). Other ethnic minority (24.32%) and Bai (18.85%) donors had a significantly higher HEV seroprevalence when compared to Han (12.21%) blood donors (odds ratio [OR], 2.25 [95% CI, 1.04-4.88] for other ethnic minority, 1.65 [95% CI, 1.24-2.19] for Bai). Conclusions: Dali, Yunnan province, China is an endemic region for HEV and have a relatively low risk of HEV transmission via blood transfusion. Whether to formulate the strategy for HEV screening in blood center needed further researched.

scholarly journals Risk for Hepatitis E Virus Transmission by Solvent/Detergent–Treated Plasma

2020 ◽  
Vol 26 (12) ◽  
pp. 2881-2886
Author(s):  
Pierre Gallian ◽  
Sébastien Lhomme ◽  
Pascal Morel ◽  
Sylvie Gross ◽  
Carole Mantovani ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Virus Transmission ◽  
Hepatitis E

A Waterborne Outbreak of Hepatitis E Virus Transmission in Southwestern Vietnam

1996 ◽  
Vol 54 (6) ◽  
pp. 559-562 ◽  
Author(s):  
Andrew Lee Corwin ◽  
Vu Thuy Yen ◽  
Junkun He ◽  
Edward T. Clayson ◽  
Pham Kim Sac ◽  
...  
Keyword(s):  
Hepatitis E Virus ◽  
Virus Transmission ◽  
Hepatitis E ◽  
Waterborne Outbreak

Prevalence of Antibody to Hepatitis E Virus among Haemodialysis Patients in Taiwan: Possible Infection by Blood Transfusion

2005 ◽  
Vol 99 (4) ◽  
pp. c122-c127 ◽  
Author(s):  
Chin-Cheng Lee ◽  
Yung-Luen Shih ◽  
Chao-Sheng Laio ◽  
Su-Mei Lin ◽  
Mei-Mei Huang ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Hepatitis E Virus ◽  
Hepatitis E

Prevalence of hepatitis E virus infection among hemodialysis patients in Japan: Evidence for infection with a genotype 3 HEV by blood transfusion

2004 ◽  
Vol 74 (4) ◽  
pp. 563-572 ◽  
Author(s):  
Takehiro Mitsui ◽  
Yukie Tsukamoto ◽  
Chikao Yamazaki ◽  
Kazuo Masuko ◽  
Fumio Tsuda ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Virus Infection ◽  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Hemodialysis Patients ◽  
Genotype 3
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