scholarly journals Impact of hookworm infection and preventive chemotherapy on haemoglobin in non‐pregnant populations

2021 ◽  
Author(s):  
Aisling Byrne ◽  
Giselle Manalo ◽  
Naomi E. Clarke ◽  
Susana Vaz Nery
Keyword(s):  
Hookworm Infection ◽  
Preventive Chemotherapy

EPIDEMIOLOGY, ECOLOGY AND PREVALENCE OF SOIL TRANSMITTED HELMINTHS FROM KOSHI REGION OF NORTH BIHAR.

2018 ◽  
Vol 24 (1) ◽  
Author(s):  
LAKSHMI CHOUDHARY ◽  
PRABHAWATI PRABHAWATI
Keyword(s):  
Relative Humidity ◽  
Ascaris Lumbricoides ◽  
Rainy Season ◽  
Climatic Factors ◽  
Trichuris Trichiura ◽  
Hookworm Infection ◽  
Soil Transmitted Helminths ◽  
High Incidence ◽  
Apparently Healthy

Prevalence of soil transmitted helminthes infections in apparently healthy school going children and other 528 people of different districts of Koshi regions of North Bihar were evaluated. Over all incidences of STHs infection was 39.39% during study. High incidence of STH was seen in the rainy season i.e., in the month of July and August, September, significantly higher (P<0.05) .The incidence of Ascaris lumbricoides was highest in the month of August (18.64%). The month of September was 15.25% followed by that of July (14.4%) and October with 10.16%. Also the incidence of hookworm registered the highest incidence in the month of June (19.27%) and lowest in the month of December (4.82%) during the study period. However prevalence of Trichuris trichiura was negligible and it was almost nil in the most of the months but was highest in month of September with 28.57% and lowest in October with 14.00% The climatic factors are responsible for soil transmitted helminthes which are temperature, rainfall and relative humidity. Ascariasis, Trichuriasis and Ancyclostomiasis (Hookworm infection) are found to be endemic in this region.

Anemia-Inducing Factor in the Early Stage of Hookworm Infection

1964 ◽  
Vol 5 (1) ◽  
pp. 37
Author(s):  
Hyun Lee ◽  
Chin-Thack Soh
Keyword(s):  
Early Stage ◽  
Hookworm Infection

The Epitome of Novel Techniques and Targeting Approaches in Drug Delivery for Treating Lymphatic Filariasis

2020 ◽  
Vol 21 (12) ◽  
pp. 1250-1263
Author(s):  
Saurabh Shrivastava ◽  
Anshita Gupta ◽  
Chanchal Deep Kaur
Keyword(s):  
Lymphatic Filariasis ◽  
Neglected Tropical Diseases ◽  
Therapeutic Interventions ◽  
Tropical Diseases ◽  
Human Beings ◽  
Therapeutic Approaches ◽  
Preventive Chemotherapy ◽  
Bioactive Substances ◽  
Lymphatic Diseases ◽  
Life Threatening

Background: Lymphatic filariasis is a pervasive and life-threatening disease for human beings. Currently, 893 million people in 49 countries worldwide affected by lymphatic filariasis as per WHO statistics. The concealed aspects of lymphatic diseases such as delayed disease detection, inappropriate disease imaging, the geographical outbreak of infection, and lack of preventive chemotherapy have brought this epidemic to the edge of Neglected Tropical Diseases. Many medications and natural bioactive substances have seen to promote filaricidal activity against the target parasitic species. However, the majority of failures have occurred in pharmaceutical and pharmacokinetic issues. Objective: The purpose of the study is to focus on the challenges and therapeutic issues in the treatment of filariasis. The review brings novel techniques and therapeutic approaches for combating lymphatic filariasis. It also offers significant developments and opportunities for such therapeutic interventions. Conclusion: Through this review, an attempt has made to critically evaluate the avenues of innovative pharmaceuticals and molecular targeting approaches to bring an integrated solution to combat lymphatic filariasis.

scholarly journals Solitary tibial lesion as the initial presentation of Langerhans cell histiocytosis: report of two cases and literature review

2021 ◽  
Vol 49 (1) ◽  
pp. 030006052098282
Author(s):  
Chih-Yang Lin ◽  
Chia-Che Lee ◽  
Kuan-Wen Wu ◽  
Chang-Tsu Yuan ◽  
Ken-Nan Kuo ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Langerhans Cell Histiocytosis ◽  
Paediatric Oncology ◽  
Bone Diseases ◽  
Langerhans Cell ◽  
Oncology Group ◽  
Preventive Chemotherapy ◽  
System Risk ◽  
Risk Patients

The various presentations of osseous Langerhans cell histiocytosis (LCH) make it difficult to distinguish from other bone diseases. In addition, there is no universally accepted protocol for managing osseous LCH for single non-central nervous system-risk lesions. Here, the rare cases of two paediatric patients, aged 1 and 2 years, who presented with a solitary tibial lesion at time of LCH diagnosis, are reported. One patient progressed to multiple lesions after curettage of the original lesion. Subsequently, both patients received preventive chemotherapy using the Taiwan Paediatric Oncology Group (TPOG) revised protocol for treating low risk patients with LCH, namely, TPOG LCH2002-LR. After receiving this treatment, which included a schedule of prednisolone and vincristine for 6 weeks, followed by prednisolone, vincristine and 6-mercaptopurine for a further 48 weeks, both patients are free from recurrence or progression.

scholarly journals Severe iron-deficiency anaemia due to hookworm infection diagnosed by capsule endoscopy

2021 ◽  
Vol 104 ◽  
pp. 271-272
Author(s):  
Hasna Chergui ◽  
Mohammad Akhoundi ◽  
Anthony Marteau ◽  
Bakhtiar Bejou ◽  
Celine Lekhal ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Capsule Endoscopy ◽  
Iron Deficiency Anaemia ◽  
Hookworm Infection ◽  
Deficiency Anaemia

scholarly journals Hookworm infection in infants: a case report and review of literature

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
G. Umbrello ◽  
R. Pinzani ◽  
A. Bandera ◽  
F. Formenti ◽  
G. Zavarise ◽  
...  
Keyword(s):  
Rural Areas ◽  
Simulation Models ◽  
Developed Countries ◽  
Hookworm Infection ◽  
Case Presentation ◽  
Abdominal Symptoms ◽  
Asymptomatic Children ◽  
Ancylostoma Duodenale ◽  
Stool Analysis ◽  
The Tropics

Abstract Background Hookworm infections (Necator americanus, Ancylostoma duodenale) are common in rural areas of tropical and subtropical countries. Human acquisition results from direct percutaneous invasion of infective larvae from contaminated soil. Overall, almost 472 million people in developing rural countries are infected. According to simulation models, hookworm disease has a global financial impact of over US$100 billion a year. Hookworm infection in newborn or infancy is rare, and most of the cases reported in literature are from endemic countries. Here, we describe the case of an infant with an Ancylostoma duodenale infection and review the literature currently available on this topic. Case presentation An Italian 2-month-old infant presented with vomit and weight loss. Her blood exams showed anemia and eosinophilia and stool analysis resulted positive for hookworms’ eggs, identified as Ancylostoma duodenale with real time-PCR. Parasite research on parents’ stools resulted negative, and since the mother travelled to Vietnam and Thailand during pregnancy, we assumed a transplacental transmission of the infection. The patient was treated successfully with oral Mebendazole and discharged in good conditions. Discussion Hookworm helminthiasis is a major cause of morbidity in children in the tropics and subtropics, but rare in developed countries. Despite most of the patients is usually asymptomatic, children are highly exposed to negative sequelae such as malnutrition, retarded growth and impaired cognitive development. In infants and newborns, the mechanism of infection remains unclear. Although infrequent, vertical transmission of larvae can occur through breastfeeding and transplacentally. Hookworm infection should be taken into account in children with abdominal symptoms and unexplained persistent eosinophilia. The treatment of infants infected by hookworm has potential benefit, but further studies are needed to define the best clinical management of these cases.

Sign in / Sign up

Export Citation Format

Share Document