Parallel enzyme-linked immunosorbent assay screening for human immunodeficiency virus among blood donors in five Chinese blood centres: a retrospective analysis

2015 ◽  
Vol 25 (4) ◽  
pp. 259-264 ◽  
Author(s):  
P. Zeng ◽  
J. Liu ◽  
J. Wang ◽  
X. Dong ◽  
J. Li ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Retrospective Analysis ◽  
Immunosorbent Assay ◽  
Blood Donors ◽  
Enzyme Linked Immunosorbent Assay ◽  
Immunodeficiency Virus

scholarly journals Seropositivity of Human Immunodeficiency Virus among Intending Blood Donors in Rivers State, Nigeria

2020 ◽  
pp. 22-29
Author(s):  
B. A. Abeni ◽  
N. Frank- Peterside ◽  
O. E. Agbagwa ◽  
S. A. Adewuyi ◽  
T. I. Cookey ◽  
...  
Keyword(s):  
Public Health ◽  
Human Immunodeficiency Virus ◽  
Blood Donors ◽  
Hiv Prevalence ◽  
Sub Saharan Africa ◽  
Enzyme Linked Immunosorbent Assay ◽  
Strict Adherence ◽  
Immunodeficiency Virus ◽  
Safe Blood ◽  
Rivers State

Aims: Provision of constant and safe blood has been a public health challenge in Sub-Saharan Africa with a high prevalence of transfusion-transmissible infections (TTIs). This study aimed at determining the seroprevalence of the Human Immunodeficiency Virus (HIV) among prospective blood donors at two Hospitals (government and private-owned) in Rivers State, and also to relate some demographic studies to the screening results. Study Design:  Cross-sectional study. Place and Duration of Study: Two Hospitals (a government-owned and private-owned) in Rivers State, Nigeria, between January 2018 and April 2019. Methodology: Two hundred and eighty-two (185 males and 97 females) blood donors were recruited for this study. Sera samples were screened for antibodies to HIV-1 and -2 using enzyme-linked immunosorbent assay (ELISA) based kits following the manufacturer’s description. Results: Of the 282 screened prospective donors (males and females) in this study, the overall prevalence of HIV from both hospitals was 6.0% with a seronegativity of 94.0%. There was a significant relationship (p <0.05) between the overall seroprevalence of HIV concerning gender (p-0.006) all other demographics had no significant association with HIV. Age group 21-30 had the highest prevalence of HIV (53.80%). Donors with tertiary education had the highest prevalence rate (52.90%) of HIV. About marital status, the unmarried donors had higher HIV prevalence (64.70%) when compared with the married donors (35.30%). However, family donors had the highest prevalence of HIV (52.90%). Finally, concerning occupation, students had a higher HIV prevalence (47.10%). Conclusion: The seroprevalence of HIV in Port Harcourt, Rivers State, Nigeria was high. This shows that HIV remains a threat to safe blood transfusion and public health in Nigeria. Strict adherence to selection criteria and algorithm of donor screening is hereby advocated.

The Fifth Consensus Conference on Testing for Human Retroviruses

1990 ◽  
Vol 11 (8) ◽  
pp. 417-418
Author(s):  
William J. Hausler ◽  
Jane P. Getchell
Keyword(s):  
Public Health ◽  
Human Immunodeficiency Virus ◽  
Western Blot ◽  
Data Sharing ◽  
Immunosorbent Assay ◽  
Consensus Conference ◽  
Enzyme Linked Immunosorbent Assay ◽  
Test Procedures ◽  
Hiv Test ◽  
Immunodeficiency Virus

In late 1985, the Association of State and Territorial Public Health Laboratory Directors (ASTPHLD) first recognized the need for standardization and uniformity of human immunodeficiency virus (HIV) test procedures, interpretation and reporting among public health laboratories. In 1986, the HIV Committee of ASTPHLD conducted its first Consensus Conference, with the objective of promoting quality and uniformity among laboratory programs through the exchange of data, sharing of expertise and formulation of consensus recommendations. There were 41 participants at this conference that addressed four topics: enzyme-linked immunosorbent assay (ELISA), Western blot, immunofluorescence and methods standardization.

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