Outcome according to subspecies following lung transplantation in cystic fibrosis pediatric patients infected with Mycobacterium abscessus

2020 ◽  
Vol 22 (3) ◽  
Author(s):  
Ema Kavaliunaite ◽  
Kathryn A. Harris ◽  
Paul Aurora ◽  
Garth Dixon ◽  
Delane Shingadia ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Pediatric Patients ◽  
Mycobacterium Abscessus

Organ Transplantation for Cystic Fibrosis

2019 ◽  
Vol 40 (06) ◽  
pp. 842-856 ◽  
Author(s):  
Matthew R. Morrell ◽  
Sarah C. Kiel ◽  
Joseph M. Pilewski
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Mycobacterium Abscessus ◽  
Mechanical Support ◽  
Early Referral ◽  
Common Indication ◽  
The Third ◽  
Atypical Pathogens ◽  
Liver And Pancreas

AbstractCystic fibrosis (CF) remains the most common indication for lung transplantation in children and the third most common in adults and has the highest median survival posttransplant for all pretransplant diagnoses. Criteria for transplant in patients with CF vary widely among transplant centers and early referral to multiple centers may be needed to maximize opportunities for lung transplantation. Comorbidities unique to CF such as resistant and atypical pathogens like Burkholderia and Mycobacterium abscessus, and cirrhosis require special consideration for lung transplantation but should not be considered as absolute contraindications. For those patients who are listed for lung transplantation, mechanical support with extracorporeal membrane oxygenation and mechanical ventilation can be efficacious as bridges to lung transplantation in experienced centers with adequate resources. Liver and pancreas transplantations are also acceptable options for end-organ disease related to CF and can provide improvements in both quantity and quality of life.

scholarly journals Lung transplantation in patients with cystic fibrosis and Mycobacterium abscessus infection

2010 ◽  
Vol 9 (4) ◽  
pp. 272-276 ◽  
Author(s):  
Marita Gilljam ◽  
Henrik Scherstén ◽  
Martin Silverborn ◽  
Bodil Jönsson ◽  
Annika Ericsson Hollsing
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Mycobacterium Abscessus

scholarly journals Successful lung transplantation for chronic Mycobacterium abscessus infection in advanced cystic fibrosis, a case series

2019 ◽  
Vol 21 (2) ◽  
pp. e13046 ◽  
Author(s):  
Daan Raats ◽  
Natalie Lorent ◽  
Veroniek Saegeman ◽  
Robin Vos ◽  
Jakko van Ingen ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Case Series ◽  
Mycobacterium Abscessus

scholarly journals Human leukocyte antigen mismatching and survival after lung transplantation in adult and pediatric patients with cystic fibrosis

2016 ◽  
Vol 151 (2) ◽  
pp. 549-557.e1 ◽  
Author(s):  
Don Hayes ◽  
Jeffery J. Auletta ◽  
Bryan A. Whitson ◽  
Sylvester M. Black ◽  
Stephen Kirkby ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Human Leukocyte Antigen ◽  
Pediatric Patients ◽  
Human Leukocyte ◽  
Leukocyte Antigen

scholarly journals 116 Lung transplantation for chronic Mycobacterium abscessus infection in advanced cystic fibrosis: a possibility?

2017 ◽  
Vol 16 ◽  
pp. S95
Author(s):  
N. Lorent ◽  
P. Van Bleyenbergh ◽  
K. Colpaert ◽  
R. Vos ◽  
V. Schaevers ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Mycobacterium Abscessus

Rhinosinusitis in the Pediatric Patient with Cystic Fibrosis

2014 ◽  
Vol 10 (3) ◽  
pp. 198-201 ◽  
Author(s):  
Christopher Fundakowski ◽  
Rosemary Ojo ◽  
Ramzi Younis
Keyword(s):  
Cystic Fibrosis ◽  
Autosomal Recessive ◽  
Pediatric Patients ◽  
Surgical Intervention ◽  
Chronic Sinusitis ◽  
Genetic Disorder ◽  
Symptomatic Relief ◽  
Recurrence Rates ◽  
Polyp Recurrence ◽  
Sinonasal Polyposis

Cystic fibrosis (CF) is a common autosomal recessive genetic disorder where a deletion mutation and subsequent downstream alteration in transmembrane regulator proteins results in increased mucus viscosity. CF manifests clinically with chronic multisystem inflammation and recurrent infections. Nearly all children with CF have chronic sinusitis, and a large majority will have concurrent sinonasal polyposis. Chronic sinusitis and sinonasal polyposis in pediatric patients with CF can be managed conservatively initially, though most will fail medical management and require surgical intervention. Unfortunately, symptom resolution is marginal and polyp recurrence rates are high. Currently, no cure exists for CF and the mainstay of treatment is to provide symptomatic relief, and minimize disease morbidity.

Outcomes Of Non‐Cystic Fibrosis Related Bronchiectasis Post Lung Transplantation

2021 ◽  
Author(s):  
Jessica Kennedy ◽  
Anne Walker ◽  
Claire M. Ellender ◽  
Kate Steinfort ◽  
Catherine Martin ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation
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