scholarly journals “Double carbapenem” and oral fosfomycin for the treatment of complicated urinary tract infections caused by bla NDM -harboring Enterobacteriaceae in kidney transplantation

2017 ◽  
Vol 20 (1) ◽  
pp. e12795 ◽  
Author(s):  
Rossana Rosa ◽  
Susan D. Rudin ◽  
Laura J. Rojas ◽  
Andrea M. Hujer ◽  
Armando Perez-Cardona ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Tract Infections

Guidance of antibiotic treatment for urinary tract infections in the early postoperative phase after Kidney Transplantation

2020 ◽  
Author(s):  
Jens Karl Hugo Strohäker ◽  
Silvio Nadalin ◽  
Alfred Königsrainer ◽  
Robert Bachmann
Keyword(s):  
Kidney Transplantation ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Asymptomatic Bacteriuria ◽  
Graft Function ◽  
Postoperative Phase ◽  
Kidney Transplant Recipients ◽  
Laboratory Findings ◽  
Gram Negative ◽  
Tract Infections

Abstract Purpose: Urinary tract infections are the most common infections early after kidney transplantation. The goals of this study were to evaluate our perioperative antibiotic protocol and risk factors for the occurrence of urinary tract and its effect on the early graft function. We evaluated laboratory alterations during episodes of UTI regarding their potential to guide treatment.Methods: Retrospective single-center analysis of all kidney transplant recipients of an academic transplant center between 2015 and 2017.Results: 96 patients were included in the study. Overall, in 22 patients a asymptomatic bacteriuria (ASB) was detected and 33 patients developed a urinary tract infection (UTI). Gram-negative UTIs appeared earlier than gram-positive UTIs. The most common lab findings during UTI were leukocytosis and CRP increase, both more common in gram-negative UTI (p .00 & .03). All complicated UTIs were caused by gram-negative bacteria (p .00). No difference in UTIs was seen between perioperative antibiotic regimens. Patients that suffered from UTIs showed less favorable graft function at discharge (GFR 43 vs 52 ml / min, p .03).Conclusion: UTIs are associated with worse graft functions while ASBs are not. Whether UTIs are caused by or lead to decreased graft function is still unclear. Proper gram-negative coverage is needed in cases of complicated UTIs or severe laboratory findings. Perioperative antibiotic regimens appear to have no beneficial influence on the incidence of UTIs.

scholarly journals URINARY TRACT INFECTIONS IN PATIENTS WHO HAVE UNDERGONE KIDNEY TRANSPLANTATION.

2010 ◽  
Vol 90 ◽  
pp. 666
Author(s):  
M. Papasotiriou ◽  
E. Savvidaki ◽  
E. Papachristou ◽  
P. Kalliakmani ◽  
M. Marangos ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Tract Infections

Urinary Tract Infections in the Early Posttransplant Period After Kidney Transplantation: Etiologic Agents and Their Susceptibility

2011 ◽  
Vol 43 (8) ◽  
pp. 2991-2993 ◽  
Author(s):  
D. Kawecki ◽  
A. Kwiatkowski ◽  
A. Sawicka-Grzelak ◽  
M. Durlik ◽  
L. Paczek ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Etiologic Agents ◽  
Tract Infections

Risk Factors for Urinary Tract Infections During the First Year After Kidney Transplantation

2010 ◽  
Vol 42 (1) ◽  
pp. 280-281 ◽  
Author(s):  
R. Sorto ◽  
S.S. Irizar ◽  
G. Delgadillo ◽  
J. Alberú ◽  
R. Correa-Rotter ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Transplantation ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
First Year ◽  
Tract Infections

Vitamin D Status has no Influence on the Incidence of Recurrent Urinary Tract Infections after Kidney Transplantation

2014 ◽  
Vol 12 (2) ◽  
pp. 114-118 ◽  
Author(s):  
Jean Jeanov Filipov ◽  
Borelli Kirilov Zlatkov ◽  
Emil Paskalev Dimitrov ◽  
Dobrin A. Svinarov
Keyword(s):  
Vitamin D ◽  
Kidney Transplantation ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Pleiotropic Effects ◽  
Kidney Transplant Recipients ◽  
Recurrent Utis ◽  
Recurrent Urinary Tract Infections ◽  
Significant Difference ◽  
Tract Infections

AbstractIntroduction.Recurrent urinary tract infections (rUTIs) after kidney transplantation (KT) are associated with significant decrease in graft survival. There is a growing body of evidence for the pleiotropic effects of vitamin D (VD), including immunomodulatory and antibacterial effect. The number of studies on VD’s pleiotropic effects in kidney transplant recipients (KTRs) however is low. The aim of our study was to assess the influence of VD on the incidence of recurrent UTIs after KT.Methods. The KTRs were tested for 25-hydroxyvitamin D (25VD) between 1.05.2012 and 30.11.2012. Patients within 12 months of transplantation, performed parathyroidectomy, concomitant intake of calcineurin inhibittors and mTOR inhibitors, advanced liver disease and VD supplementation were excluded from the study. Recurrent UTIs were defined as more than 3 episodes of active UTI within the last 12 months of testing for 25VD. Statistical analysis was carried out with SPSS version 22.0 and included descriptive statistics, Mann-Whitney U test. Determination of total 25VD was performed by a validated LC-MS/MS method.Results.A total of 275 patients met the above-mentioned criteria (males 182, females 93). The mean 25VD in patients with rUTIs (n=14) was 51.41±25.17 nmol/L, whereas in the group without rUTIs (n=261) the level was 60.35±23.29 nmol/L. After matching the two groups for seasonal factors (sampling for 25VD in July, August, September) and gender 169 patients were selected, and 11 were with rUTIs. No significant difference was detected in the 25VD level in the two groups (53.30±18.37 vs 49.08±21.04 nmol/L), p=0.342.Conclusions.Despite the higher 25VD in the KTRs without rUTIs, the difference between the two groups remained insignificant.

THE EVOLUTION OF THE ETIOLOGY OF BACTERIAL URINARY TRACT INFECTIONS AFTER KIDNEY TRANSPLANTATION

2010 ◽  
Vol 90 ◽  
pp. 661
Author(s):  
M. Nowicki ◽  
M. Wajdlich ◽  
M. Mascidlo ◽  
Z. Zbrog ◽  
I. Kurnatowska
Keyword(s):  
Kidney Transplantation ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Tract Infections
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