The relationship of HLA-class I derived leader peptide mismatch and renal function within the first 12 months post-renal transplant

2013 ◽  
pp. n/a-n/a
Author(s):  
R. Battle ◽  
N. Woodroofe ◽  
M. Clench ◽  
B. Clark
1990 ◽  
Vol 13 (2) ◽  
pp. 142-148 ◽  
Author(s):  
Kazuyuki Morita ◽  
Junko Moriuchi ◽  
Yukinobu Ichikawa ◽  
Kimiyoshi Tsuji ◽  
Shigeru Arimori

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Manan Al-Hakbany ◽  
Sitalbanat Awadallah ◽  
Laila AL-Ayadhi

Earlier reports showed the relationship between autism and immune genes located in the human leukocyte antigen (HLA). In this current study, we compared the HLA class I and class II alleles and haplotypes in 35 autistic children with 100 control subjects from Saudi Arabia, using PCR-SSP method and Luminex technology. In class I the HLA-A*01 (P=0.03, OR 2.68), A*02 (P=0.001, OR 3.02) and HLA-B*07 (P=0.01, OR 3.27), were significantly associated with autism. Also, the haplotype A*02-B*07 was significantly higher in autistic patients than in controls (P=0.007, OR 5.83). In class II, DRB1*1104 was significantly higher in patients than in controls (P=0.001, OR 8.75). The DQB1*0202 (P=0.001,OR 0.24), DQB1*0302 (P=0.001,OR 0.14), and DQB1*0501 (P=0.012,OR 0.25), were negatively associated with disease. While the four-loci genotype study showed that A*01-B*07-DRB1*0701-DQB1*0602 (P=0.001,OR 41.9) and the A*31-B*51-DRB1*0103-DQB1*0302 (P=0.012,OR 4.8) are positively associated with autism among Saudi patients. This is the first report on a foreseeable risk of association of HLA-B*07 allele with autism. Thus, HLA-B*07 allele and the closely linked haplotype A*01 B*07 DRB1*0701 DQB1*0602 may serve as a marker for genetic susceptibility to autism in Saudis.


1997 ◽  
Vol 56 ◽  
pp. 240
Author(s):  
S. Daniel ◽  
V. Brusic ◽  
S. Caillat-Zucman ◽  
N. Petrovsky ◽  
L. Harrison ◽  
...  

2018 ◽  
Vol 20 (6) ◽  
pp. 1027-1035 ◽  
Author(s):  
Yueh-Hung Lin ◽  
Kuo-Tzu Sung ◽  
Cheng-Ting Tsai ◽  
Pei-Chen Wu ◽  
Yau-Huei Lai ◽  
...  

2020 ◽  
Vol 9 (10) ◽  
pp. e1839108586
Author(s):  
Marcio da Costa Almeida ◽  
Paula Cotrin ◽  
Fabricio Pinelli Valarelli ◽  
Rodrigo Hermont Cançado ◽  
Ricardo Cesar Gobbi de Oliveira ◽  
...  

The objective of this work was to determine the prevalence of individual traits of malocclusion in a sample of three Brazilian regions orthodontic patients and to detect interregional population differences in the prevalence of certain occlusal characteristics.  The present study was based on the examination of dental casts, intraoral photographs and panoramic radiographs of 947 orthodontic patients from 3 cities: 363 from Fortaleza (CE), 270 from Maringá (PR) and 314 from Bauru (SP), respectively, representing the Northeast, South and Southeast Brazilian regions. The relationship of the first maxillary and mandibular molars according to Angle’s classification, overjet, overbite, crowding, posterior crossbite and maxillary median diastema were examined. The chi-square and ANOVA tests were used to determine potential differences in the distribution of malocclusion when stratified Brazilian regions. Class I malocclusion was found in 499 (52.69%), Class II in 395 (41.71%) and Class III malocclusion in 53 (5,59%) subjects of all examined. Deep overbite (3.59%), midline diastemas (5.17%) and posterior crossbite (4.75%) were observed more frequently in Bauru; however, in Maringá, normal overbite (13.3%) and open bite (4.75%) were more prevalent. The results of this study showed that Class I malocclusion was the most prevalent, followed by Class II and Class III malocclusions. These occlusal relationships evaluated in the three Brazilian regions follow the same pattern of frequency as the result presented by the general population of the sample.


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