Skin barrier response to active chlorine hand disinfectant—An experimental study comparing skin barrier response to active chlorine hand disinfectant and alcohol‐based hand rub on healthy skin and eczematous skin

2021 ◽  
Author(s):  
Yasemin Topal Yüksel ◽  
Mie Sonne ◽  
Line Brok Nørreslet ◽  
Glenn Gundersen ◽  
Magnus Mustafa Fazli ◽  
...  
Keyword(s):  
Experimental Study ◽  
Skin Barrier ◽  
Active Chlorine ◽  
Healthy Skin

16437 Effects of cleansing on skin barrier function in atopic dermatitis and healthy skin: A pilot study

2020 ◽  
Vol 83 (6) ◽  
pp. AB63
Author(s):  
Aleksi J. Hendricks ◽  
Bryan W. Kromenacker ◽  
Alyssa Thompson ◽  
Elizabeth I. Mata ◽  
Catherine M. Ludwig ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Pilot Study ◽  
Barrier Function ◽  
Skin Barrier ◽  
Skin Barrier Function ◽  
Healthy Skin

scholarly journals Sensitive skin and its management

2021 ◽  
Vol 1 ◽  
pp. 53
Author(s):  
Iffat Hassan ◽  
Kewal Krishan
Keyword(s):  
Psychosocial Factors ◽  
Climate Changes ◽  
Skin Barrier ◽  
Diagnostic Methods ◽  
Clinical Aspects ◽  
Healthy Skin ◽  
Contributing Factors ◽  
Sensitive Skin ◽  
Factors Affecting ◽  
Chemical Stimuli

Sensitive skin is a self-diagnosed condition and is usually not accompanied by any obvious physical signs of irritation. Patients with this syndrome usually have unpleasant sensations whenever exposed to any physical, thermal or chemical stimuli that normally cause no provocation on healthy skin. Cosmetics, skin barrier impairment, and climate changes are the main contributing factors for skin hyperactivity. Although diagnosis is challenging due to lack of any specific or preferred diagnostic methods and interventions, recent studies on different clinical aspects of sensitive skin have provided new approaches to the diagnosis, management and interventions targeting the pathophysiology and treatment of sensitive skin syndrome. In general, patients with sensitive skin need an individual approach, keeping in view the various biomedical, neural, and psychosocial factors affecting sensitive skin.

scholarly journals Short-term effects of vacuum massage on epidermal and dermal thickness and density in burn scars: an experimental study

2016 ◽  
Vol 4 ◽  
pp. 1-9 ◽  
Author(s):  
Jill Meirte ◽  
Peter Moortgat ◽  
Mieke Anthonissen ◽  
Koen Maertens ◽  
Cynthia Lafaire ◽  
...  
Keyword(s):  
Experimental Study ◽  
Skin Barrier ◽  
Scar Tissue ◽  
Mechanical Stimuli ◽  
Short Term ◽  
Post Intervention ◽  
Non Invasive ◽  
Dermal Thickness ◽  
External Stimuli ◽  
Short Term Effects

Abstract Background Vacuum massage is a non-invasive mechanical massage technique invented to treat burns and scars. To date, no effects of vacuum massage on thickness and density of human scar tissue have been reported. The process in which external stimuli are converted into biochemical responses in the cell is known as mechanotransduction. In the skin endothelial cells, fibroblasts and myofibroblasts embedded in the extracellular matrix (ECM) sense mechanical stimuli (created by vacuum massage) and may promote intracellular processes leading to matrix remodelling. Since mechanotransduction could be a plausible working mechanism for vacuum massage as an anti-scarring therapy, this study aims to investigate the short-term effects of vacuum massage on thickness and density of epidermis and dermis in burn scars in order to find proof of ECM remodelling. Methods A one group experimental study was performed. Patients with burn scars on upper extremities, lower extremities, and trunk were recruited for participation in this study. The DUB®cutis 22 MHz ultrasound scanner was used to assess thickness and density of the epidermal and dermal skin layers. After baseline measurements, vacuum massage was performed according to a pre-defined protocol. Measurements were carried out at 5 min, 30 min, 1 h, and 2 h post-intervention. Results Thirteen scar sites from 9 different patients were investigated. In 8 out of the 13 scar sites, a disruption of the epidermis was noticed after the vacuum massage. Five minutes after the intervention, epidermal density decreased statistically significantly (p = .022) and dermal thickness increased (p = .018). Both changes lasted for more than 1 h, but after 2 h, the changes were no longer statistically significant. Dermal density decreased significantly (p = .048) immediately after the intervention, and this decrease was still present after 2 h (p = .011). Conclusions Preliminary results show that the disruption of the epidermis may indicate that vacuum massage could be able to actually breach the skin barrier. The statistically significant changes in the dermal layers could suggest an increased ECM production after vacuum massage.

Experimental study on the restoration from a tilt-azimuth series for improvement in resolution

1995 ◽  
Vol 53 ◽  
pp. 636-637
Author(s):  
Norio Baba ◽  
Norihiko Ichise ◽  
Syunya Watanabe
Keyword(s):  
Experimental Study ◽  
Spherical Aberration ◽  
Incident Beam ◽  
Optical Parameters ◽  
Beam Tilting ◽  
Illumination Method ◽  
Restoration Method ◽  
Illumination Mode

The tilted beam illumination method is used to improve the resolution comparing with the axial illumination mode. Using this advantage, a restoration method of several tilted beam images covering the full azimuthal range was proposed by Saxton, and experimentally examined. To make this technique more reliable it seems that some practical problems still remain. In this report the restoration was attempted and the problems were considered. In our study, four problems were pointed out for the experiment of the restoration. (1) Accurate beam tilt adjustment to fit the incident beam to the coma-free axis for the symmetrical beam tilting over the full azimuthal range. (2) Accurate measurements of the optical parameters which are necessary to design the restoration filter. Even if the spherical aberration coefficient Cs is known with accuracy and the axial astigmatism is sufficiently compensated, at least the defocus value must be measured. (3) Accurate alignment of the tilt-azimuth series images.

Changes in corneocyte element concentrations occur in skin inner stratum corneum

1990 ◽  
Vol 48 (2) ◽  
pp. 146-147
Author(s):  
R. R. Warner
Keyword(s):  
Stratum Corneum ◽  
Human Skin ◽  
Element Concentration ◽  
Skin Barrier ◽  
Barrier Properties ◽  
Brick Wall ◽  
Inorganic Elements ◽  
Dry Skin ◽  
Skin Biopsies ◽  
Intercellular Lipid

Keratinocytes undergo maturation during their transit through the viable layers of skin, and then abruptly transform into flattened, anuclear corneocytes that constitute the cellular component of the skin barrier, the stratum corneum (SC). The SC is generally considered to be homogeneous in its structure and barrier properties, and is often shown schematically as a featureless brick wall, the “bricks” being the corneocytes, the “mortar” being intercellular lipid. Previously we showed the outer SC was not homogeneous in its composition, but contained steep gradients of the physiological inorganic elements Na, K and Cl, likely originating from sweat salts. Here we show the innermost corneocytes in human skin are also heterogeneous in composition, undergoing systematic changes in intracellular element concentration during transit into the interior of the SC.Human skin biopsies were taken from the lower leg of individuals with both “good” and “dry” skin and plunge-frozen in a stirred, cooled isopentane/propane mixture.

An Experimental Study of Some Properties of Stuttered Words

1962 ◽  
Vol 5 (4) ◽  
pp. 387-394 ◽  
Author(s):  
Bruce Quarrington ◽  
Jerome Conway ◽  
Nathan Siegel
Keyword(s):  
Experimental Study
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