scholarly journals Methods Matter: Nonsuicidal Self‐Injury in the Form of Cutting is Uniquely Associated with Suicide Attempt Severity in Patients with Substance Use Disorders

2020 ◽  
Vol 50 (2) ◽  
pp. 397-407
Author(s):  
Margaret M. Baer ◽  
Matthew T. Tull ◽  
Courtney N. Forbes ◽  
Julia R. Richmond ◽  
Kim L. Gratz
2016 ◽  
Vol 3 (4) ◽  
Author(s):  
Dr Vaddadi. Venkata kiran ◽  
Dr. Neeli Uma Jyothi ◽  
Mounica. Bollu

Suicide attempt is a deliberate act of self harm with at least some intent of die that does not result in death. Such act has a wide range of medical seriousness. Individuals with psychiatric disorders are far more likely to commit suicide than the others. People who are psychologically disabled are often commit suicide from years of pain, frustration and depression. Spiritually they may perceive themselves as hopelessly damaged and lose all sense of purpose and meaning of life. Suicide is not a diagnosis or a disorder. it is a behaviour. Suicide is a worldwide, national, local and familial problem. 90% of people who kill themselves suffer from a diagnosable and preventable problem such as depression co-occurring mental and substance use disorders are common and potent combination among those who die by suicide.


2021 ◽  
pp. 1-19
Author(s):  
Zeynep Başgöze ◽  
Salahudeen A. Mirza ◽  
Thanharat Silamongkol ◽  
Dawson Hill ◽  
Conner Falke ◽  
...  

Abstract Nonsuicidal self-injury (NSSI) is a common but poorly understood phenomenon in adolescents. This study examined the Sustained Threat domain in female adolescents with a continuum of NSSI severity (N = 142). Across NSSI lifetime frequency and NSSI severity groups (No + Mild NSSI, Moderate NSSI, Severe NSSI), we examined physiological, self-reported and observed stress during the Trier Social Stress Test; amygdala volume; amygdala responses to threat stimuli; and resting-state functional connectivity (RSFC) between amygdala and medial prefrontal cortex (mPFC). Severe NSSI showed a blunted pattern of cortisol response, despite elevated reported and observed stress during TSST. Severe NSSI showed lower amygdala–mPFC RSFC; follow-up analyses suggested that this was more pronounced in those with a history of suicide attempt for both moderate and severe NSSI. Moderate NSSI showed elevated right amygdala activation to threat; multiple regressions showed that, when considered together with low amygdala–mPFC RSFC, higher right but lower left amygdala activation predicted NSSI severity. Patterns of interrelationships among Sustained Threat measures varied substantially across NSSI severity groups, and further by suicide attempt history. Study limitations include the cross-sectional design, missing data, and sampling biases. Our findings highlight the value of multilevel approaches in understanding the complexity of neurobiological mechanisms in adolescent NSSI.


Crisis ◽  
2019 ◽  
Vol 40 (3) ◽  
pp. 166-175 ◽  
Author(s):  
Alexandre Mikhail ◽  
Omaid Tanoli ◽  
Gilles Légaré ◽  
Pierre-André Dubé ◽  
Youssef Habel ◽  
...  

Abstract. Background: Over-the-counter (OTC) analgesics are frequently used in suicide attempts. Accessibility, toxicity, and unsupervised acquisition of large amounts may be facilitators. Aims: To identify patient characteristics associated with OTC drug use as a suicide attempt method among adults. Method: A cross-sectional study was conducted using chart review of all individuals who presented to the emergency department (ED) of two adult general hospitals following a suicide attempt during 2009–2010 in Montreal, Canada. Results: Among the 369 suicide attempters identified, 181 used overdosing, 47% of whom used OTC drugs. In logistic regression, women and those with medical comorbidity were more likely to use overdosing, while those with substance use disorders were less likely to do so. Among those who overdosed, women were more likely to use OTC drugs, while those who were Caucasian, had children, comorbidities, diagnoses with substance use disorders, and made attempts in the Fall were less likely to do so. Substances most frequently used were: acetaminophen among OTC drugs (30%); antidepressants (37%), anxiolytics (30%), opioids (10%), and anticonvulsants (9%) among prescription drugs; and cocaine (10%) among recreational drugs. Limitations: Reasons for the suicide method choice were not available. Conclusion: OTC drugs, in particular acetaminophen, are frequently used in suicide attempts. Accessibility to these drugs may be an important contributor.


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