scholarly journals P2‐6: Folliculin haploinsufficiency causes cellular dysfunction of pleural mesothelial cells

Respirology ◽  
2021 ◽  
Vol 26 (S3) ◽  
pp. 115-115
Keyword(s):  
Mesothelial Cells ◽  
Pleural Mesothelial Cells ◽  
Cellular Dysfunction

Lrp1 Regulates Urokinase Receptor-Dependent Pathophysiologic Responses Of Human Pleural Mesothelial Cells

2011 ◽  
Author(s):  
Torry A. Tucker ◽  
LaTerrica Williams ◽  
Kathy Koenig ◽  
Hema Kothari ◽  
Andrey Komissarov ◽  
...  
Keyword(s):  
Mesothelial Cells ◽  
Urokinase Receptor ◽  
Pleural Mesothelial Cells

Long-Term Chronic Toxicity and Mesothelial Cell Reactions Induced by Potassium Octatitanate Fibers (TISMO) in the Left Thoracic Cavity in A/J Female Mice

2015 ◽  
Vol 34 (4) ◽  
pp. 325-335 ◽  
Author(s):  
Masanao Yokohira ◽  
Nozomi Hashimoto ◽  
Toshitaka Nakagawa ◽  
Yuko Nakano ◽  
Keiko Yamakawa ◽  
...  
Keyword(s):  
Mesothelial Cell ◽  
Mesothelial Cells ◽  
Mouse Lung ◽  
Thoracic Cavity ◽  
Direct Effects ◽  
Pleural Mesothelial Cells ◽  
Chronic Effects ◽  
Trade Name ◽  
Potassium Octatitanate Fibers

The present study was conducted to examine the chronic effects of potassium octatitanate fibers (trade name TISMO; chemical formula K2O·6TiO2) on the mouse lung and thoracic cavity. This method of infusion was employed to examine the direct effects of the fibers to the pleura. In the present study, 52- and 65-week experiments were employed to examine the long-term chronic effects after infusion of fiber-shaped TISMO into the thoracic cavities of A/J mice. Following this infusion, TISMO fibers were observed in the alveoli, indicating penetration through the visceral pleura. The additional histopathological detection of TISMO fibers in the liver, spleen, kidneys, ovary, heart, bone marrow, and brain of TISMO-infused mice indicated migration of the fibers out from the thoracic cavity. Atypical mesothelial cells with severe pleural proliferation were observed, but malignant mesotheliomas were not detected. This study demonstrated that intrathoracic infusion of TISMO fiber did not cause malignant mesothelioma but did cause severe chronic inflammation and proliferation of pleural mesothelial cells.

scholarly journals Co-Transcriptomes of Initial Interactions In Vitro between Streptococcus Pneumoniae and Human Pleural Mesothelial Cells

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0142773 ◽  
Author(s):  
Claire J. Heath ◽  
Maria del Mar Cendra ◽  
Alastair Watson ◽  
Jean-Philippe Auger ◽  
Anish Pandey ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Mesothelial Cells ◽  
Pleural Mesothelial Cells

Role of oxygen derivatives in the cytotoxicity and DNA damage produced by asbestos on rat pleural mesothelial cells in vitro

1994 ◽  
Vol 15 (6) ◽  
pp. 1251-1255 ◽  
Author(s):  
Hang Ying Dong ◽  
Annie Buard ◽  
Annie Renier ◽  
Francoise Lévy ◽  
Laure Saint-Etienne ◽  
...  
Keyword(s):  
Dna Damage ◽  
Mesothelial Cells ◽  
Pleural Mesothelial Cells

Synthesis of poly(ADP-ribose) in asbestos treated rat pleural mesothelial cells in culture

1995 ◽  
Vol 331 (2) ◽  
pp. 197-204 ◽  
Author(s):  
Hang Ying Dong ◽  
Annie Buard ◽  
Françoise Lévy ◽  
Annie Renier ◽  
Françoise Laval ◽  
...  
Keyword(s):  
Mesothelial Cells ◽  
Cells In Culture ◽  
Pleural Mesothelial Cells
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