scholarly journals BALANCED CRYSTALLOIDS VS NORMAL SALINE SOLUTION AS INTRAVENOUS FLUID THERAPY AMONG CRITICALLY ILL PATIENTS: A META-ANALYSIS

Respirology ◽  
2018 ◽  
Vol 23 ◽  
pp. 261-261
Keyword(s):  
Critically Ill ◽  
Fluid Therapy ◽  
Normal Saline ◽  
Critically Ill Patients ◽  
Saline Solution ◽  
Meta Analysis ◽  
Intravenous Fluid ◽  
Intravenous Fluid Therapy ◽  
Balanced Crystalloids

scholarly journals Balanced crystalloids for intravenous fluid therapy in critically ill and non-critically ill patients

Medicine ◽  
2018 ◽  
Vol 97 (51) ◽  
pp. e13683
Author(s):  
Peifen Ma ◽  
Bo Wang ◽  
Jun Zhang ◽  
Xiping Shen ◽  
Liping Yu ◽  
...  
Keyword(s):  
Critically Ill ◽  
Fluid Therapy ◽  
Critically Ill Patients ◽  
Intravenous Fluid ◽  
Intravenous Fluid Therapy ◽  
Balanced Crystalloids

scholarly journals Balanced crystalloids compared to normal saline for fluid therapy in critically ill adult patients: Systematic review and meta-analysis protocol

2021 ◽  
Author(s):  
Naomi E Hammond ◽  
Fernando G Zampieri ◽  
Tessa Garside ◽  
Derek Adigbli ◽  
Gian Luca Di Tanna ◽  
...  
Keyword(s):  
Systematic Review ◽  
Critically Ill ◽  
Fluid Therapy ◽  
Normal Saline ◽  
Meta Analysis ◽  
Scientific Journal ◽  
Risk Of Bias ◽  
Adult Patients ◽  
Primary Data ◽  
Salt Solutions

Introduction The choice of intravenous fluid for fluid therapy in critically ill adult patients remains a matter of debate. Currently, crystalloids are used more often than colloids, with ongoing controversy over the relative efficacy and safety of buffered salt solutions (BSS) versus normal saline (0.9% sodium chloride). In 2021 two large pragmatic trials enrolling critically ill patients will add substantial new data to address this controversy. We will conduct a systematic review and meta-analysis of randomised controlled trials (RCTs) that will include the data from these two trials to provide clinicians with the most up to date evidence and robust evidence to guide their choice of crystalloid fluids. Methods and analysis We will include RCTs that compare the effect of buffered salt solutions to normal saline for fluid resuscitation and/or fluid therapy in critically ill adults, on all-cause mortality and other patient centred outcomes. We will perform a search that includes the electronic databases MEDLINE and EMBASE, and clinical trial registries. Two reviewers will independently screen titles and abstracts, perform full article reviews and extract study data, with discrepancies resolved by a third reviewer. We will report study characteristics and assess risk of bias using the Cochrane Risk-of-Bias tool. We will perform Hartung-Knapp-Sidik-Jonkman random-effects aggregate data meta-analysis whenever it is feasible to do so. We will evaluate overall certainty of evidence using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework. Ethics and dissemination This systematic review and meta-analysis does not require ethical approval as it does not involve primary data collection. We will publish our results in a peer-reviewed scientific journal and present them at national and international scientific conferences. PROSPERO registration number: CRD42021243399

scholarly journals Balanced crystalloids versus isotonic saline in critically ill patients: systematic review and meta-analysis

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Yazan Z. M. Zayed ◽  
Ahmed M. Y. Aburahma ◽  
Mahmoud O. Barbarawi ◽  
Kewan Hamid ◽  
Momen R. N. Banifadel ◽  
...  
Keyword(s):  
Systematic Review ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Meta Analysis ◽  
Isotonic Saline ◽  
Balanced Crystalloids

Isotonic versus hypotonic saline solution for maintenance intravenous fluid therapy in children: a systematic review

2015 ◽  
Vol 30 (7) ◽  
pp. 1163-1172 ◽  
Author(s):  
April P. Padua ◽  
Josep Ryan G. Macaraya ◽  
Leonila F. Dans ◽  
Francisco E. Anacleto
Keyword(s):  
Systematic Review ◽  
Fluid Therapy ◽  
Saline Solution ◽  
Intravenous Fluid ◽  
Intravenous Fluid Therapy ◽  
Hypotonic Saline
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