scholarly journals A CASE OF OSTEOSARCOMA LUNG METASTASIS WITH LONG-TERM SURVIVAL BY MULTIDISCIPLINARY TREATMENT CENTERED ON MULTIPLE SURGICAL EXCISION

Respirology ◽  
2018 ◽  
Vol 23 ◽  
pp. 165-165
Keyword(s):  
Lung Metastasis ◽  
Multidisciplinary Treatment ◽  
Surgical Excision ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Long-term survival with multiple metastasectomies for pulmonary osteosarcoma: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Satoshi Takamori ◽  
Hiroyuki Oizumi ◽  
Jun Suzuki ◽  
Katsuyuki Suzuki
Keyword(s):  
Case Report ◽  
Pulmonary Metastases ◽  
Multidisciplinary Treatment ◽  
Underlying Disease ◽  
Pulmonary Metastasectomy ◽  
Extensive Resection ◽  
Term Survival ◽  
Long Term Survival ◽  
Primary Surgery

Abstract Background Repeat pulmonary metastasectomy (PM) considerably improves the prognosis of patients with pulmonary metastases of osteosarcoma. Reports have demonstrated a significantly improved prognosis in patients who have undergone repeat metastasectomy for osteosarcoma; however, there have been no reports with more than six metastasectomies. Herein, we describe the long-term survival of a patient following resection of multiple tumors and other treatments for metastatic osteosarcoma. Case presentation A 28-year-old woman underwent extensive resection and postoperative adjuvant chemotherapy for right tibial sarcoma. Over the years, she developed repeated pulmonary metastases. First, 116 metastases were removed from the bilateral lungs. After that, multiple PMs of approximately 250 tumors and other treatments for deep metastatic lesions were performed. The patient died of the underlying disease 24 years after the primary surgery. Conclusions This case report demonstrates the long-term survival benefit of a multidisciplinary treatment centered on multiple metastasectomies.

scholarly journals Cardiac Metastasis from Medullary Thyroid Cancers with Long-Term Survival under Vandetanib

2021 ◽  
pp. 1-6
Author(s):  
Camille Buffet ◽  
Sophie Leboulleux ◽  
Françoise Kraeber-Bodéré ◽  
Caroline Bodet-Milin ◽  
Laure Cabanes ◽  
...  
Keyword(s):  
Kinase Inhibitor ◽  
Surgical Excision ◽  
Cardiac Metastasis ◽  
Term Survival ◽  
Long Term Survival ◽  
Thyroid Cancers ◽  
Medullary Thyroid ◽  
Cardiac Metastases

<b><i>Background:</i></b> Cardiac metastases from thyroid cancers are uncommon with a poor prognosis. There is a lack of long-term follow-up studies. <b><i>Cases:</i></b> We report 2 cases of cardiac metastasis from medullary thyroid cancer (MTC). Both patients presented limited metastatic disease apart from a cardiac metastasis. The initial diagnosis was challenging and was facilitated by functional imaging with an immuno-PET-CT using an anti-CEA bispecific antibody and a <sup>68</sup>Ga-labeled peptide. Both patients were treated with the multitarget kinase inhibitor vandetanib with prolonged stability. The first patient was alive at the last follow-up, 14 years after the diagnosis of cardiac metastasis. The second patient required surgical excision of the cardiac mass because of disease progression under vandetanib. <b><i>Conclusion:</i></b> These cases illustrate long-term survival and effectiveness of clinical management of 2 patients who developed cardiac metastases from MTC, in the current era of personalized medicine with targeted therapy.

scholarly journals LONG-TERM SURVIVAL OF METASTATIC CLEAR CELL ADENOCARCINOMA OF THE FEMALE URETHRA BY MULTIDISCIPLINARY TREATMENT: A CASE REPORT

2013 ◽  
Vol 104 (3) ◽  
pp. 549-553
Author(s):  
Takahisa Suzuki ◽  
Hiroshi Furuse ◽  
Yutaka Kurita ◽  
Takeshi Imanishi ◽  
Keita Tamura ◽  
...  
Keyword(s):  
Case Report ◽  
Clear Cell ◽  
Multidisciplinary Treatment ◽  
Clear Cell Adenocarcinoma ◽  
Female Urethra ◽  
Term Survival ◽  
Long Term Survival

Long-Term Survival in a Rare Case of Malignant Esophageal Schwannoma Cured by Surgical Excision

2011 ◽  
Vol 92 (1) ◽  
pp. 357-358 ◽  
Author(s):  
Shaohua Wang ◽  
Jian Zheng ◽  
Zheng Ruan ◽  
Hailong Huang ◽  
Zhaorui Yang ◽  
...  
Keyword(s):  
Rare Case ◽  
Surgical Excision ◽  
Term Survival ◽  
Long Term Survival ◽  
Esophageal Schwannoma

scholarly journals LONG-TERM SURVIVAL AFTER MULTIPLE SYNOVIAL SARCOMA LUNG-METASTASIS RESECTIONS

2008 ◽  
Vol 69 (8) ◽  
pp. 1897-1901
Author(s):  
Yoshitsugu YAMADA ◽  
Rieko KITAGAWA ◽  
Takemichi SUTO ◽  
Daisuke KIMURA ◽  
Takao TSUSHIMA ◽  
...  
Keyword(s):  
Synovial Sarcoma ◽  
Lung Metastasis ◽  
Term Survival ◽  
Long Term Survival

scholarly journals Confirmed complete response to nivolumab for advanced gastric cancer with peritoneal dissemination: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Tomoya Takami ◽  
Koji Yasuda ◽  
Nozomi Uozumi ◽  
Yutaka Musiake ◽  
Hiroshi Shintani ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Adverse Events ◽  
Peritoneal Dissemination ◽  
Multidisciplinary Treatment ◽  
Term Survival ◽  
Long Term Survival ◽  
Recurrent Gastric Cancer

Abstract Background Recent advances in cancer immunotherapy have been remarkable, with many reports on the clinical effects of immune checkpoint inhibitors. Nivolumab has been covered by the national health insurance in Japan as a third-line agent for advanced and recurrent gastric cancer since September 2017. The objective response rate for nivolumab for gastric cancer is 11.2%. However, patients’ quality of life during this treatment has not been examined. Here, we report a case in which multidisciplinary treatment, including with nivolumab, resulted in long-term survival and improved quality of life. Case presentation A 70-year-old Asian woman was referred for surgery for gastric cancer. Postoperative pathological examination revealed peritoneal dissemination, and the patient was diagnosed with stage IV gastric cancer. Therefore, she was treated with S-1 and cisplatin based on negative immunohistochemical staining of resected specimens for human epidermal growth factor receptor 2. However, owing to instability and adverse events, treatment was subsequently changed to S-1 monotherapy. Two years after changing to S-1 monotherapy, she developed recurrence of peritoneal dissemination and was treated with docetaxel. Radiation therapy was also used because the recurrent lesions were local. However, 6 months later, new peritoneal dissemination and lymph node metastasis were observed and nivolumab was started. Subsequent abdominal computed tomography revealed a marked reduction in the disseminated nodules and lymphadenopathy. After 54 cycles of nivolumab, the lesions had disappeared completely. The patient has not developed side effects, including immune-responsive adverse events, has improved quality of life, and is returning to work. She is currently taking nivolumab, and there is no evidence of recurrence approximately 3 years after starting nivolumab. Conclusions Nivolumab may have beneficial effects in some patients with advanced or recurrent gastric cancer. Although the prognosis for gastric cancer and peritoneal dissemination is poor, multidisciplinary treatment that includes nivolumab may lead to long-term survival.

scholarly journals A Case of Metastatic Sarcomatoid Renal Cell Carcinoma Which Obtained Long-Term Survival by Multidisciplinary Treatment

2014 ◽  
Vol 25 ◽  
pp. v109
Author(s):  
Hiroshi Yaegashi ◽  
Kouji Izumi ◽  
Satoru Ueno ◽  
Yuji Maeda ◽  
Yoshifumi Kadono ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Multidisciplinary Treatment ◽  
Term Survival ◽  
Long Term Survival ◽  
Sarcomatoid Renal Cell Carcinoma

scholarly journals A Case Report of Long-Term Survival following Hepatic Arterial Infusion ofL-Folinic Acid Modulated 5-Fluorouracil Combined with Intravenous Irinotecan and Cetuximab Followed by Hepatectomy in a Patient with Initially Unresectable Colorectal Liver Metastases

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Kobe Van Bael ◽  
Yanina Jansen ◽  
Teofila Seremet ◽  
Benedikt Engels ◽  
Georges Delvaux ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Folinic Acid ◽  
Metabolic Response ◽  
Multidisciplinary Treatment ◽  
Hepatic Arterial Infusion ◽  
Invasive Adenocarcinoma ◽  
Arterial Infusion ◽  
Term Survival ◽  
Long Term Survival

A 43-year-old women admitted to our hospital for weight loss, anorexia, and abdominal pain was diagnosed with sigmoid neoplasm and multiple bilobar liver metastases. This patient received six cycles of systemic FOLFOX prior to a laparoscopically assisted anterior resection of the rectosigmoid for a poorly differentiated invasive adenocarcinoma T2N2M1, K-RAS negative (wild type). Hepatic arterial infusion (HAI) ofL-folinic acid modulated 5-fluorouracil (LV/5-FU) with intravenous (iv) irinotecan (FOLFIRI) and cetuximab as adjuvant therapy resulted in a complete metabolic response (CR) with CEA normalization. A right hepatectomy extended to segment IV was performed resulting in (FDG-)PET negative remission for 7 months. Solitary intrahepatic recurrence was effectively managed by local radiofrequent ablation following 6c FOLFIRI plus cetuximab iv. Multiple lung lesions and recurrence of pulmonary and local lymph node metastases were successfully treated with fractionated stereotactic radiotherapy (50 Gy) and iv LV/5-FU/oxaliplatin (FOLFOX) plus cetuximab finally switched to panitumumab with CR as a result. At present the patient is in persistent complete remission of her stage IV colorectal cancer, more than 5 years after initial diagnosis of the advanced disease. Multidisciplinary treatment with HAI of chemotherapy (LV/5-FU + CPT-11) plus EGFR-inhibitor can achieve CR of complex unresectable LM and can even result in hepatectomy with possible long-term survival.

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