scholarly journals THE CLINICAL ANALYSIS OF PULMONARY LYMPHOEPITHELIOMA-LIKE CARCINOMA WITH EPITHELIOID GRANULOMA: FOURTEEN CASES AND LITERATURE REVIEW

Respirology ◽  
2018 ◽  
Vol 23 ◽  
pp. 20-21
2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e20545-e20545
Author(s):  
Yinyin Qin

e20545 Background: Pulmonary lymphoepithelioma-like carcinoma (PLELC) is a rare subtype of non-small cell lung cancer associated with Epstein-bar virus (EBV) infection. Even less reported were those with Epithelioid granuloma (EG) and were frequently misdiagnosed. Current study aimed at investigating the clinical presentation, pathological characteristics and treatments of PLELC complicated with EG to improve our understanding of this disease. Methods: Data was collected from January 2013 to December 2017. A total of 105 patients were diagnosed as PLELC, in which 14 patients were with EG. Their clinical features, pathological characteristics and treatment were analyzed. Results: The 14 patients with EG (13.3%) in our group were followed-up 15 months (10-31 months).The median age was 48.5 year-old (38-67 year-old) and 85.7% were under the age of 60, meanwhile females had a slightly higher proportion than males (1.8:1). Most patients were at early stage (71.4%) with nonspecific manifestations such as cough, expectoration and lack of rich-lewis phenomenon. EG were often located in tumor or beside the tumor (71.4%), others were located in lymph node. It was all negative in specific stain of pathology and all positive in situ hybridization of EBV-encoded RNA (EBER). In our study, two patients received palliative chemotherapy with the duration of progression-free survival in 8 and 10 months, respectively. Twelve patients underwent surgical resection including ten with adjuvant or neo-adjuvant chemotherapy. Three patients had disease relapsed in 8, 13 and 25 months after surgery, respectively. None of them had tuberculosis occurring, progression or relapse, even if anti-tuberculosis therapy were not taken. Conclusions: PLELC complicated with EG, a rare phenomenon, was lack of rich-lewis phenomenon and specific clinical characteristic compared with those without EG. The formation of EG may be caused by immunological hypersensitivity to tumor cell or EBV infection instead of tuberculosis. It was important for us to make an exact pathological diagnosis, and attention should be paid to obtain samples by biopsy and make differential diagnosis. PLELC complicated with EG could receive multimodality therapy such as chemotherapy and surgery. However, anti-tuberculosis therapy was not necessary.


2001 ◽  
Vol 25 (7) ◽  
pp. 848-855 ◽  
Author(s):  
Wen-Yao Yin ◽  
Hwa-Tzong Chen ◽  
Shih-Ming Huang ◽  
Hsien-Hong Lin ◽  
Tzu-Ming Chang

2016 ◽  
Vol 17 (5) ◽  
pp. 562-570 ◽  
Author(s):  
Orit Nuttman-Shwartz ◽  
Yael Shoval-Zuckerman

This article presents a literature review of the concept of continuous traumatic situations (CTS), which relates to residents living in ongoing situations of political violence and national security threats. The first aim of this review is to narrow the gap regarding knowledge about the concept of CTS by presenting findings from studies that have assessed the effects of CTS on civilian populations. The second aim is to describe CTS in a way that highlights the differences and similarities between posttraumatic stress disorder and responses to CTS. This distinction is a necessary precondition for examining CTS, as is a careful clinical analysis of the development and course of symptoms. This literature review also highlights the importance of adopting a supplementary perspective for understanding the psychological impact of ongoing exposure to real threats, which can be used as a basis for developing intervention strategies that are appropriate for coping with life in the context of persistent violence. CTS can be manifested as emotions, behaviors, and perceptions among individuals, families, communities, and societies. The nature of the proposed model of CTS is a circular one, combining past and future perceptions and emotional reactions that have resulted from continuous and repeated traumatic experiences over an extended period of time. This wider understanding reflects the complexity of the CTS phenomenon. Various micro and macro interventions relating to CTS as the result of political violence situations and national security threats are presented, and recommendations for practice, policy, and future research are offered.


2019 ◽  
Vol 15 (3) ◽  
pp. 192 ◽  
Author(s):  
Jing Kong ◽  
Liwei Pang ◽  
Jindong Yuan ◽  
Yan Zhang ◽  
Yuwen Wang

2018 ◽  
Vol 46 (9) ◽  
pp. 3630-3639 ◽  
Author(s):  
Xiaoyi Wu ◽  
Wei Jiang ◽  
Huan Xu ◽  
Xuping Ye ◽  
Congjian Xu

Objective An increasing trend of uterine rupture (UR) after laparoscopic surgery of the uterus (LSU) has been observed. Although the overall incidence is extremely low, UR may have catastrophic outcomes. Therefore, investigation of its potential risk factors is important. Methods We retrospectively reviewed the medical data of 10 women who developed UR after LSU performed at our hospital from October 2003 to October 2016 and conducted a literature review. Results All cases of UR occurred during the third trimester of pregnancy. The surgeries contributing to UR were laparoscopic myomectomy, adhesion decomposition, and salpingectomy, resulting in unfavorable outcomes especially for the fetus. Diathermy was routinely used for hemostasis, and multilayer suturing was not adequately performed in many cases. The posterior wall was the most common site of UR in most cases. Silent rupture with unremarkable symptoms was not rare. Similar risk factors were identified in the literature review. Conclusions Excessive use of energy equipment and the lack of multilayer suturing were the most common characteristics of UR after LSU. A history of LSU should always be considered a risk factor for UR.


2014 ◽  
Vol 21 (6) ◽  
pp. 283-290 ◽  
Author(s):  
Wei-Hsi Chen ◽  
Chang-Hung Chen ◽  
Chi Chui ◽  
Chun-Chung Lui ◽  
Chung-Jen Chen ◽  
...  

2020 ◽  
Vol 9 (2) ◽  
pp. 1023-1031
Author(s):  
Guoying Gao ◽  
Chengzhi Zhou ◽  
Guofeng Wu ◽  
Weijie Guan ◽  
Guosheng Deng ◽  
...  

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