Expression of aquaporin 4 in the chicken oviduct following tamoxifen treatment

2018 ◽  
Vol 53 (6) ◽  
pp. 1339-1346 ◽  
Author(s):  
Joanna K. Socha ◽  
Noboru Saito ◽  
Dominika Wolak ◽  
Andrzej Sechman ◽  
Anna Hrabia
Keyword(s):  
Aquaporin 4 ◽  
Tamoxifen Treatment ◽  
Chicken Oviduct

scholarly journals Aquaporin 4 in the chicken oviduct during a pause in laying induced by food deprivation

2020 ◽  
Vol 343 (1) ◽  
pp. 89-99
Author(s):  
Anna Hrabia ◽  
Joanna K. Socha ◽  
Noboru Saito ◽  
Małgorzata Grzesiak ◽  
Andrzej Sechman
Keyword(s):  
Food Deprivation ◽  
Aquaporin 4 ◽  
Chicken Oviduct

LIGHT AND ELECTRON MICROSCOPICAL STUDY OF THE EFFECT OF OESTROGEN ON THE CHICKEN OVIDUCT

1967 ◽  
Vol 56 (3) ◽  
pp. 391-402 ◽  
Author(s):  
H. I. Ljungkvist
Keyword(s):  
Secretory Granules ◽  
Apical Cell ◽  
Cell Types ◽  
Microscopical Study ◽  
List Type ◽  
New Production ◽  
General Increase ◽  
Chicken Oviduct ◽  
Electron Microscopical ◽  
Aortic Perfusion

ABSTRACT Oviducts from 20 one-day old chickens were used. Ten chickens were injected subcutaneously with 0.2 mg oestradiol for 5 days, the remaining ones serving as controls. The chickens were fixed by an aortic perfusion with 2.5% glutaraldehyde in phosphate buffer, pH 7.2. The treatment with oestrogen resulted in the following changes: general increase in oviduct length and thickness, differentiation of the epithelial membrane into three cell types: basal, apical and gland cells, increase in the number of cilia in the apical cell, probably due to a new production of cilia, formation of secretory granules in the vaginal epithelium as seen by light microscopy, formation of proteinlike secretory granules in the apical cell as seen by electron microscopy, increase in protein synthesis, observed as an augmentation of the endoplasmic reticulum.

Beneficial Effects of Tamoxifen Treatment in Type 1 Diabetes

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2155-P
Author(s):  
JUAN ZHENG ◽  
MOHAMMAD ISHRAQ ZAFAR ◽  
LULU CHEN ◽  
XIN GUO ◽  
XIAOMING LI
Keyword(s):  
Type 1 Diabetes ◽  
Tamoxifen Treatment ◽  
Beneficial Effects

Aquaporin 4 in Astrocytes is a Target for Therapy in Alzheimer's Disease

2018 ◽  
Vol 23 (33) ◽  
Author(s):  
Yu-Long Lan ◽  
Jian-Jiao Chen ◽  
Gang Hu ◽  
Jun Xu ◽  
Ming Xiao ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Aquaporin 4

Cerebrolysin and Aquaporin 4 Inhibition Improve Pathological and Motor Recovery after Ischemic Stroke

2018 ◽  
Vol 17 (4) ◽  
pp. 299-308 ◽  
Author(s):  
Bogdan Catalin ◽  
Otilia-Constantina Rogoveanu ◽  
Ionica Pirici ◽  
Tudor Adrian Balseanu ◽  
Adina Stan ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Vasogenic Edema ◽  
Artery Occlusion ◽  
Aquaporin 4 ◽  
Hypertonic Solution ◽  
Water Metabolism ◽  
Scar Region ◽  
Function Preservation ◽  
Neurotropic Factor ◽  
Cerebral Artery Occlusion

Background: Edema represents one of the earliest negative markers of survival and consecutive neurological deficit following stroke. The mixture of cellular and vasogenic edema makes treating this condition complicated, and to date, there is no pathogenically oriented drug treatment for edema, which leaves parenteral administration of a hypertonic solution as the only non-surgical alternative. Objective: New insights into water metabolism in the brain have opened the way for molecular targeted treatment, with aquaporin 4 channels (AQP4) taking center stage. We aimed here to assess the effect of inhibiting AQP4 together with the administration of a neurotropic factor (Cerebrolysin) in ischemic stroke. Methods: Using a permanent medial cerebral artery occlusion rat model, we administrated a single dose of the AQP4 inhibitor TGN-020 (100 mg/kg) at 15 minutes after ischemia followed by daily Cerebrolysin dosing (5ml/kg) for seven days. Rotarod motor testing and neuropathology examinations were next performed. Results: We showed first that the combination treatment animals have a better motor function preservation at seven days after permanent ischemia. We have also identified distinct cellular contributions that represent the bases of behavior testing, such as less astrocyte scarring and a larger neuronalsurvival phenotype rate in animals treated with both compounds than in animals treated with Cerebrolysin alone or untreated animals. Conclusion: Our data show that water diffusion inhibition and Cerebrolysin administration after focal ischemic stroke reduces infarct size, leading to a higher neuronal survival in the peri-core glial scar region.

Adenosarcoma of the uterus following tamoxifen treatment for breast cancer

1998 ◽  
Vol 8 (2) ◽  
pp. 168-171 ◽  
Author(s):  
Mourits ◽  
Hollema ◽  
Willemse ◽  
de Vries ◽  
Aalders ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tamoxifen Treatment
Sign in / Sign up

Export Citation Format

Share Document