Effect of different parietal hypoperfusion on neuropsychological characteristics in mild cognitive impairment

2021 ◽  
Author(s):  
Tatsuya Yamaguchi ◽  
Hajime Tabuchi ◽  
Daisuke Ito ◽  
Naho Saito ◽  
Bun Yamagata ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Characteristics

Neurocognitive Deficits and Effects of Cognitive Reserve in Mild Cognitive Impairment

2016 ◽  
Vol 41 (3-4) ◽  
pp. 199-209 ◽  
Author(s):  
Nadeshda Andrejeva ◽  
Maren Knebel ◽  
Vasco Dos Santos ◽  
Janna Schmidt ◽  
Christina Josefa Herold ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Reserve ◽  
Neurocognitive Deficits ◽  
Cognitive Domains ◽  
Amnestic Mci ◽  
Increased Risk ◽  
Neuropsychological Characteristics ◽  
Executive Deficits ◽  
Multiple Domain

Background/Aims: Mild cognitive impairment (MCI) is a frequent syndrome in the older population, which involves an increased risk to develop Alzheimer's disease (AD). The latter can be modified by the cognitive reserve, which can be operationalized by the length of school education. MCI can be differentiated into four subtypes according to the cognitive domains involved: amnestic MCI, multiple-domain amnestic MCI, non-amnestic MCI and multiple-domain non-amnestic MCI. While neurocognitive deficits are a constituent of the diagnosis of these subtypes, the question of how they refer to the cognitive reserve still needs to be clarified. Methods: We examined neuropsychological deficits in healthy controls, patients with MCI and patients with mild AD (n = 485) derived from a memory clinic. To reduce the number of neuropsychological variables, a factor analysis with varimax rotation was calculated. In a second step, diagnostic groups including MCI subtypes were compared with respect to their clinical and neuropsychological characteristics including cognitive reserve. Results: Most MCI patients showed the amnestic multiple-domain subtype followed by the pure amnestic subtype, while the non-amnestic subtypes were rare. The amnestic subtype displayed a significantly higher level of cognitive reserve and higher MMSE scores than the amnestic multiple-domain subtype, which was in most cases characterized by additional psychomotor and executive deficits. Conclusions: These findings confirm earlier reports revealing that the amnestic multiple-domain subtype is the most frequent one and indicating that a high cognitive reserve may primarily prevent psychomotor and executive deficits in MCI.

P4-062: Neuropsychological characteristics of people with mild cognitive impairment with or without depression

2013 ◽  
Vol 9 ◽  
pp. P725-P726
Author(s):  
Kwang Seok Jeong ◽  
So Young Youn ◽  
Un Jung Cho ◽  
Chan-Seung Chung ◽  
Seung Hyun Song ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Characteristics

Neuropsychological characteristics of individuals with mild cognitive impairment

2016 ◽  
Vol 33 (S1) ◽  
pp. S366-S366
Author(s):  
Q. Wang ◽  
Y. Sheng
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Executive Function ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Early Stage ◽  
Control Group ◽  
Neuropsychological Characteristics ◽  
The Difference ◽  
Competing Interest

IntroductionAs the population ages, cognitive impairment is prevalent among older adults and this may cause a huge burden to society. In order to take precautions effectively, we need to understand the characteristics of cognitive function of older adults, especially the individuals with mild cognitive impairment (MCI).ObjectivesTo explore the characteristics of cognitive function changes in individuals with mild cognitive impairment.MethodsA total of 108 individuals with MCI as MCI group and 108 volunteers as control group were recruited in the study. The age, gender and years of schooling were matched between the two groups. The cognitive function was evaluated with the Montreal Cognitive Assessment (MoCA).ResultsIndividuals of MCI group performed poorer than those of control group on executive function, attention, calculation, language and delayed memory. The difference between the two groups was statistically significant (P < 0.05). The cognitive impairment in participants with MCI were delayed memory (100%), language (75%), executive function (66.7%), attention (44%) and calculation (20.4%).ConclusionsThe impairment of memory, language and executive function is the primary characteristics in individuals with MCI. Individuals with MCI have similar characteristics with early stage Alzheimer's disease (AD). We should take preventive measures to improve or delay AD.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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