Association between brain amyloid accumulation and neuropsychological characteristics in elders with depression and mild cognitive impairment

2019 ◽  
Vol 34 (12) ◽  
pp. 1907-1915 ◽  
Author(s):  
HyunChul Youn ◽  
Suji Lee ◽  
Changsu Han ◽  
Seung‐Hyun Kim ◽  
Hyun‐Ghang Jeong
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Amyloid Accumulation ◽  
Neuropsychological Characteristics

Effect of different parietal hypoperfusion on neuropsychological characteristics in mild cognitive impairment

2021 ◽  
Author(s):  
Tatsuya Yamaguchi ◽  
Hajime Tabuchi ◽  
Daisuke Ito ◽  
Naho Saito ◽  
Bun Yamagata ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Characteristics

Lifetime History of Depression Predicts Increased Beta-Amyloid Accumulation in Patients with Mild Cognitive Impairment

2015 ◽  
Vol 23 (3) ◽  
pp. S147-S150 ◽  
Author(s):  
Jun Ku Chung ◽  
Eric Plitman ◽  
Shinichiro Nakajima ◽  
Tiffany W. Chow ◽  
Mallar Chakravarty ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Beta Amyloid ◽  
Lifetime History ◽  
Amyloid Accumulation ◽  
History Of ◽  
History Of Depression

Neurocognitive Deficits and Effects of Cognitive Reserve in Mild Cognitive Impairment

2016 ◽  
Vol 41 (3-4) ◽  
pp. 199-209 ◽  
Author(s):  
Nadeshda Andrejeva ◽  
Maren Knebel ◽  
Vasco Dos Santos ◽  
Janna Schmidt ◽  
Christina Josefa Herold ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Reserve ◽  
Neurocognitive Deficits ◽  
Cognitive Domains ◽  
Amnestic Mci ◽  
Increased Risk ◽  
Neuropsychological Characteristics ◽  
Executive Deficits ◽  
Multiple Domain

Background/Aims: Mild cognitive impairment (MCI) is a frequent syndrome in the older population, which involves an increased risk to develop Alzheimer's disease (AD). The latter can be modified by the cognitive reserve, which can be operationalized by the length of school education. MCI can be differentiated into four subtypes according to the cognitive domains involved: amnestic MCI, multiple-domain amnestic MCI, non-amnestic MCI and multiple-domain non-amnestic MCI. While neurocognitive deficits are a constituent of the diagnosis of these subtypes, the question of how they refer to the cognitive reserve still needs to be clarified. Methods: We examined neuropsychological deficits in healthy controls, patients with MCI and patients with mild AD (n = 485) derived from a memory clinic. To reduce the number of neuropsychological variables, a factor analysis with varimax rotation was calculated. In a second step, diagnostic groups including MCI subtypes were compared with respect to their clinical and neuropsychological characteristics including cognitive reserve. Results: Most MCI patients showed the amnestic multiple-domain subtype followed by the pure amnestic subtype, while the non-amnestic subtypes were rare. The amnestic subtype displayed a significantly higher level of cognitive reserve and higher MMSE scores than the amnestic multiple-domain subtype, which was in most cases characterized by additional psychomotor and executive deficits. Conclusions: These findings confirm earlier reports revealing that the amnestic multiple-domain subtype is the most frequent one and indicating that a high cognitive reserve may primarily prevent psychomotor and executive deficits in MCI.

P4-062: Neuropsychological characteristics of people with mild cognitive impairment with or without depression

2013 ◽  
Vol 9 ◽  
pp. P725-P726
Author(s):  
Kwang Seok Jeong ◽  
So Young Youn ◽  
Un Jung Cho ◽  
Chan-Seung Chung ◽  
Seung Hyun Song ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Neuropsychological Characteristics

Cognitive Decline and Amyloid Accumulation in Patients with Mild Cognitive Impairment

2012 ◽  
Vol 34 (1) ◽  
pp. 31-37 ◽  
Author(s):  
Jaana Koivunen ◽  
Mira Karrasch ◽  
Noora M. Scheinin ◽  
Sargo Aalto ◽  
Tero Vahlberg ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Decline ◽  
Amyloid Accumulation
Sign in / Sign up

Export Citation Format

Share Document