Personal computer-based cognitive training in Parkinson's disease: a case study

2018 ◽  
Vol 18 (5) ◽  
pp. 427-429 ◽  
Author(s):  
Maria G. Maggio ◽  
Rosaria De Luca ◽  
Giuseppa Maresca ◽  
Giuseppe Di Lorenzo ◽  
Desiree Latella ◽  
...  
2019 ◽  
Vol 44 (4) ◽  
pp. 555-567 ◽  
Author(s):  
Sara Bernini ◽  
Anna Alloni ◽  
Silvia Panzarasa ◽  
Marta Picascia ◽  
Silvana Quaglini ◽  
...  

2020 ◽  
Vol 35 (4) ◽  
pp. 434-447 ◽  
Author(s):  
Anastasia Nousia ◽  
Maria Martzoukou ◽  
Zisis Tsouris ◽  
Vasileios Siokas ◽  
Athina-Maria Aloizou ◽  
...  

Abstract Background Cognitive dysfunction is one of the most prevalent non-motor aspects of Parkinson’s disease (PD). The present review focuses on published studies investigating the effect of computer-based cognitive training (CT) on neuropsychological performance in PD. Methods A systematic search of the PubMed database and Google Scholar was carried out. Randomized controlled studies published before September 2019, investigating the effect of computer-based CT (regardless of the comparator, active or placebo) on PD patients were included. Literature search, data extraction, and Risk of Bias (RoB) evaluation (based on the RoB Cochrane tool for Randomized Trials) were performed by two authors (A.N. and M.M), independently. Results Among 30 full-texts assessed for eligibility, seven articles fulfilled the inclusion criteria and were involved in the qualitative analysis. The main outcomes of the retrieved studies (all studies used similar cognitive rehabilitation methodologies) were indicative of cognitive improvement in most cognitive domains, particularly memory, executive function, processing speed, and attention, that is, the domains primarily impaired in the disease. Conclusion Multidomain CT, which is exclusively based on computer software, leads to measurable improvements in most cognitive domains affected in patients with PD. The present review is the first to include studies assessing the effect of computer-based CT techniques without deploying CT with paper-pencil techniques. Limitations originate mainly due to the heterogeneity among included studies (differences in CT softwares, PD stages, number, and duration of training sessions.


2021 ◽  
pp. 1-3
Author(s):  
Tobias Loetscher

BACKGROUND: The majority of people living with Parkinson’s disease will develop impairments in cognition. These impairments are associated with a reduced quality of life. OBJECTIVE: The Cochrane Review aimed to investigate whether cognitive training improves cognition in people with Parkinson’s disease and mild cognitive impairments or dementia. METHODS: A Cochrane Review by Orgeta et al. was summarized with comments. RESULTS: The review included seven studies with a total of 225 participants. There was no evidence for improvements in global cognition when cognitive training was compared to control conditions. Observed improvements in attention and verbal memory measures after cognitive training could not be confirmed in a subsequent sensitivity analysis. There was no evidence for benefits in other cognitive domains or quality of life measures. The certainty of the evidence was low for all comparisons. CONCLUSIONS: The effectiveness of cognitive training for people with Parkinson’s disease and cognitive impairments remains inconclusive. There is a pressing need for adequately powered trials with higher methodological quality.


2020 ◽  
Vol Volume 13 ◽  
pp. 1545-1546
Author(s):  
Marty Hinz ◽  
Alvin Stein ◽  
Thomas Uncini

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