scholarly journals Corrigendum to: The Beneficial Effects of Computer-Based Cognitive Training in Parkinson’s Disease: A Systematic Review

2020 ◽  
Author(s):  
Anastasia Nousia ◽  
Maria Martzoukou ◽  
Zisis Tsouris ◽  
Vasileios Siokas ◽  
Athina-Maria Aloizou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Training ◽  
Beneficial Effects ◽  
Computer Based

A computer-based cognitive training in Mild Cognitive Impairment in Parkinson’s Disease

2019 ◽  
Vol 44 (4) ◽  
pp. 555-567 ◽  
Author(s):  
Sara Bernini ◽  
Anna Alloni ◽  
Silvia Panzarasa ◽  
Marta Picascia ◽  
Silvana Quaglini ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Training ◽  
Computer Based

scholarly journals The Beneficial Effects of Computer-Based Cognitive Training in Parkinson’s Disease: A Systematic Review

2020 ◽  
Vol 35 (4) ◽  
pp. 434-447 ◽  
Author(s):  
Anastasia Nousia ◽  
Maria Martzoukou ◽  
Zisis Tsouris ◽  
Vasileios Siokas ◽  
Athina-Maria Aloizou ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Training ◽  
Cognitive Rehabilitation ◽  
Present Review ◽  
Cognitive Domains ◽  
Cognitive Improvement ◽  
Randomized Controlled Studies ◽  
Pubmed Database ◽  
Computer Based

Abstract Background Cognitive dysfunction is one of the most prevalent non-motor aspects of Parkinson’s disease (PD). The present review focuses on published studies investigating the effect of computer-based cognitive training (CT) on neuropsychological performance in PD. Methods A systematic search of the PubMed database and Google Scholar was carried out. Randomized controlled studies published before September 2019, investigating the effect of computer-based CT (regardless of the comparator, active or placebo) on PD patients were included. Literature search, data extraction, and Risk of Bias (RoB) evaluation (based on the RoB Cochrane tool for Randomized Trials) were performed by two authors (A.N. and M.M), independently. Results Among 30 full-texts assessed for eligibility, seven articles fulfilled the inclusion criteria and were involved in the qualitative analysis. The main outcomes of the retrieved studies (all studies used similar cognitive rehabilitation methodologies) were indicative of cognitive improvement in most cognitive domains, particularly memory, executive function, processing speed, and attention, that is, the domains primarily impaired in the disease. Conclusion Multidomain CT, which is exclusively based on computer software, leads to measurable improvements in most cognitive domains affected in patients with PD. The present review is the first to include studies assessing the effect of computer-based CT techniques without deploying CT with paper-pencil techniques. Limitations originate mainly due to the heterogeneity among included studies (differences in CT softwares, PD stages, number, and duration of training sessions.

scholarly journals Computerised cognitive training in Parkinson’s disease: a protocol for a systematic review and updated meta-analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e040656
Author(s):  
Hanna Malmberg Gavelin ◽  
Magdalena Domellöf ◽  
Isabella Leung ◽  
Anna Stigsdotter Neely ◽  
Carsten Finke ◽  
...  
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Function ◽  
Cognitive Training ◽  
Risk Of Bias ◽  
Effect Sizes ◽  
Motor Symptom ◽  
Intervention Design ◽  
Design Factors

IntroductionCognitive impairment is recognised as an important non-motor symptom in Parkinson’s disease (PD) and there is a need for evidence-based non-pharmacological interventions that may prevent or slow cognitive decline in this patient group. One such intervention is computerised cognitive training (CCT), which has shown efficacious for cognition across older adult populations. This systematic review aims to investigate the efficacy of CCT across cognitive, psychosocial and functional domains for people with PD and examine study and intervention design factors that could moderate CCT effects on cognition.Methods and analysisRandomised controlled trials investigating the effects of CCT in patients with PD without dementia, on cognitive, psychosocial or functional outcomes, will be included. The primary outcome is overall cognitive function. Secondary outcomes are domain-specific cognitive function, psychosocial functioning and functional abilities. We systematically searched MEDLINE, Embase and PsycINFO through 14 May 2020 to identify relevant literature. Risk of bias will be assessed using the revised Cochrane Risk of Bias tool. Effect sizes will be calculated as standardised mean difference of baseline to postintervention change (Hedges’ g) with 95% CI for each eligible outcome measure. Pooling of outcomes across studies will be conducted using random-effects models, accounting for dependency structure of effect sizes within studies. Heterogeneity will be assessed using τ2 and I2 statistic. Potential moderators, based on key study and intervention design factors, will be investigated using mixed-effects meta-regression models.Ethics and disseminationNo ethical approval is required. The findings will be disseminated in a peer-reviewed scientific journal.PROSPERO registration numberCRD42020185386.

Personal computer-based cognitive training in Parkinson's disease: a case study

2018 ◽  
Vol 18 (5) ◽  
pp. 427-429 ◽  
Author(s):  
Maria G. Maggio ◽  
Rosaria De Luca ◽  
Giuseppa Maresca ◽  
Giuseppe Di Lorenzo ◽  
Desiree Latella ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cognitive Training ◽  
Personal Computer ◽  
Computer Based

Neuroplasticity mediated by motor rehabilitation in Parkinson’s disease: a systematic review on structural and functional MRI markers

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Francesca Baglio ◽  
Alice Pirastru ◽  
Niels Bergsland ◽  
Marta Cazzoli ◽  
Eleonora Tavazzi
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Structural Response ◽  
The Elderly ◽  
Quantitative Mri ◽  
Motor Rehabilitation ◽  
Surgical Interventions ◽  
Beneficial Effects ◽  
Meta Analyses

Abstract Parkinson’s disease (PD) is the second most common neurological disease affecting the elderly population. Pharmacological and surgical interventions usually employed for PD treatment show transient effectiveness and are associated with the insurgence of side effects. Therefore, motor rehabilitation has been proposed as a promising supplement in the treatment of PD, reducing the global burden of the disease and improving patients quality of life. The present systematic review aimed to critically analyse the literature concerning MRI markers of brain functional and structural response to motor rehabilitation in PD. Fourteen out of 1313 studies were selected according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Despite the limited number of retrieved studies coupled with their heterogeneity prevent ultimate conclusions from being drawn, motor rehabilitation seems to have beneficial effects on PD as measured both with clinical outcomes and MRI derived indices. Interestingly, consistent results seem to indicate that motor rehabilitation acts via a dual mechanism of strengthening cortico-subcortical pathways, restoring movements automaticity, or activating compensatory networks such as the fronto-parietal one. The employment of more advanced and quantitative MRI methods is warranted to establish and validate standardized metrics capable of reliably determining the changes induced by rehabilitative intervention.

scholarly journals Benefits of Pilates in Parkinson’s Disease: A Systematic Review and Meta-Analysis

Medicina ◽  
2019 ◽  
Vol 55 (8) ◽  
pp. 476 ◽  
Author(s):  
David Suárez-Iglesias ◽  
Kyle J. Miller ◽  
Manuel Seijo-Martínez ◽  
Carlos Ayán
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Positive Impact ◽  
Meta Analysis ◽  
Scientific Evidence ◽  
Descriptive Analysis ◽  
Preliminary Evidence ◽  
Beneficial Effects ◽  
Training Programmes

Pilates may be a beneficial method of exercise for people with Parkinson’s disease (PD). However, no studies have critically reviewed the scientific evidence in this regard. The purpose of this study was to conduct a systematic review and meta-analysis on the effectiveness of Pilates as a rehabilitation strategy for PD. A systematic search of the electronic databases PubMed, PEDro, Scopus, and SPORTDiscus was conducted to identify studies related to the effect of Pilates on PD. The search timeframe ranged from the inception of each database to March 2019. The search resulted in the identification of four randomized controlled trials (RCTs) and four non-RCT studies. The methodological quality of the investigations ranged from poor to fair. The descriptive analysis of the eight investigations showed that Pilates resulted in beneficial effects on fitness, balance and functional autonomy. A subsequent meta-analysis on the four RCTs indicated that Pilates was more effective than traditional training programmes in improving lower limb function. Pilates can be safely prescribed for people with mild-to-moderate PD. Preliminary evidence indicates that its practice could have a positive impact on fitness, balance and physical function. Its benefits on lower-body function appear to be superior to those of other conventional exercises. Future randomized studies with greater samples are needed to confirm these observations.

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