scholarly journals Adenocarcinoma arising in small sessile serrated adenoma/polyp (SSA/P) of the colon: Clinicopathological study of eight lesions

2014 ◽  
Vol 64 (3) ◽  
pp. 123-132 ◽  
Author(s):  
Shinichi Ban ◽  
Hiroyuki Mitomi ◽  
Hisashi Horiguchi ◽  
Hideaki Sato ◽  
Michio Shimizu
Keyword(s):  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Clinicopathological Study

scholarly journals Mo1739 – Molecular Markers, Mlh1 and Msi Status Differentiate Hyperplastic Polyps from Sessile Serrated Adenoma/Polyps Among African American Patients

2019 ◽  
Vol 156 (6) ◽  
pp. S-828
Author(s):  
Hassan Ashktorab ◽  
Priyanka Kanth ◽  
Nazli Atefi ◽  
Saman Azam ◽  
Babak Shokrani ◽  
...  
Keyword(s):  
African American ◽  
Molecular Markers ◽  
Hyperplastic Polyps ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma

scholarly journals Sessile serrated adenoma invading a diverticulum in the right colon: tips and tricks for a safe complete endoscopic resection

Endoscopy ◽  
2021 ◽  
Author(s):  
Sophie Geyl ◽  
Jérémie Albouys ◽  
Romain Legros ◽  
Hugo Lepetit ◽  
Martin Dahan ◽  
...  
Keyword(s):  
Endoscopic Resection ◽  
Tips And Tricks ◽  
Right Colon ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
The Right

scholarly journals Endoscopic Observation of the Growth Process of a Right-Side Sessile Serrated Adenoma/Polyp with Cytological Dysplasia to an Invasive Submucosal Adenocarcinoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Kaoru Omori ◽  
Kanako Yoshida ◽  
Sadafumi Tamiya ◽  
Tsutomu Daa ◽  
Masahiro Kan
Keyword(s):  
Narrow Band Imaging ◽  
Rapid Progression ◽  
Imaging Features ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Small Nodule ◽  
Circular Pattern ◽  
Endoscopic Observation ◽  
Submucosal Adenocarcinoma ◽  
The Right

A sessile serrated adenoma/polyp (SSA/P) with cytological dysplasia in the right colon, which transformed to an invasive submucosal adenocarcinoma finally, was endoscopically observed in a 76-year-old woman. A whitish soft SSA/P (approximately 25 mm in diameter) was detected in the cecum. Biopsy samples were obtained from the small nodule, and the lesion was eventually diagnosed as an SSA/P with cytological dysplasia, considering endoscopic observations, among which the narrow-band imaging features suggested that the lesion was adenomatous, that is, a round-oval pattern, and hyperplastic, that is, comprising a circular pattern with dots and an invisible capillary vessel. After 11 months, an SSA/P had rapidly developed into a submucosal adenocarcinoma with lymphatic infiltrations, and the most aggressive deep invasion was observed in the central depression. This case suggests that right-side SSA/Ps with cytological dysplasia should be removed immediately, considering the potential for rapid progression to a larger size and eventually to deep and extensive cancer.

Adjunctive use of chromoendoscopy may improve the diagnostic performance of narrow-band imaging for small sessile serrated adenoma/polyp

2018 ◽  
Vol 33 (2) ◽  
pp. 466-474 ◽  
Author(s):  
Li-Chun Chang ◽  
Chia-Hung Tu ◽  
Been-Ren Lin ◽  
Chia-Tung Shun ◽  
Weng-Feng Hsu ◽  
...  
Keyword(s):  
Diagnostic Performance ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma

scholarly journals Use of endocytoscopy for identification of sessile serrated adenoma/polyps and hyperplastic polyps by quantitative image analysis of the luminal areas

2017 ◽  
Vol 05 (08) ◽  
pp. E769-E774 ◽  
Author(s):  
Yushi Ogawa ◽  
Shin-ei Kudo ◽  
Yuichi Mori ◽  
Nobunao Ikehara ◽  
Yasuharu Maeda ◽  
...  
Keyword(s):  
Roc Analysis ◽  
Normal Mucosa ◽  
Receiver Operating Curve ◽  
Hyperplastic Polyps ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Important Indicator ◽  
Cutoff Value ◽  
Luminal Area ◽  
Magnifying Chromoendoscopy

Abstract Background and study aims Recent studies that used magnifying chromoendoscopy and endocytoscopy (EC) to investigate endoscopic features of sessile serrated adenoma/polyps (SSA/Ps) suggested that a dilated crypt opening was an important indicator of SSA/Ps. However, no studies to date have measured the actual extent of dilatation. Hence, we investigated retrospectively the luminal areas using EC to determine a cutoff value for differentiating SSA/Ps from hyperplastic polyps (HPs). Patients and methods A total of 101 lesions, including 25 SSA/Ps, 66 HPs, and 10 normal mucosal samples, assessed by an integrated-type EC were collected. For each lesion, 1 image that showed the widest lumen was selected and the average area of the contiguous 3 lumens were calculated. The cutoff value differentiating SSAPs from HPs was determined by receiver operating curve (ROC) analysis. Results The mean luminal areas of SSA/Ps and HPs were 4152 μm2 and 2117 μm2, respectively. ROC analysis found that a luminal area cutoff of 3068 μm2 had a sensitivity of 80.0 %, a specificity of 77.3 %, an accuracy of 78.0 %, and an area under the ROC curve of 0.865. Furthermore, a cutoff of ≥ 556 μm2 was found to accurately distinguish between HPs and normal mucosa (sensitivity 98.5 %, specificity 100 %, accuracy 98.7 %, and AUC 0.998). Conclusions EC analysis of the luminal area is useful for differentiating between SSAPs and HPs. This approach could be adapted for computer-aided diagnosis of SSA/P.

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