scholarly journals Aliphatic β-Nitroalcohols for Therapeutic Corneoscleral Cross-Linking: Chemical Stability Studies Using1H-NMR Spectroscopy

2013 ◽  
Vol 90 (2) ◽  
pp. 338-343
Author(s):  
Xia Li ◽  
Yongjun Li ◽  
MiJung Kim ◽  
Stephen L. Trokel ◽  
Nicholas J. Turro ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Chemical Stability ◽  
Cross Linking ◽  
Stability Studies

Functionality and chemical stability of plasma polymer films exhibiting a vertical cross-linking gradient in their subsurface

2018 ◽  
Vol 156 ◽  
pp. 259-268 ◽  
Author(s):  
Marianne Vandenbossche ◽  
Johanna Dorst ◽  
Martin Amberg ◽  
Urs Schütz ◽  
Patrick Rupper ◽  
...  
Keyword(s):  
Polymer Films ◽  
Chemical Stability ◽  
Plasma Polymer ◽  
Cross Linking

Mechanism for Peroxide Cross-Linking of EPDM Rubber from MAS13C NMR Spectroscopy

2009 ◽  
Vol 42 (22) ◽  
pp. 8914-8924 ◽  
Author(s):  
R. A. Orza ◽  
P. C. M. M. Magusin ◽  
V. M. Litvinov ◽  
M. van Duin ◽  
M. A. J. Michels
Keyword(s):  
Nmr Spectroscopy ◽  
Cross Linking ◽  
Epdm Rubber

Stability Studies of Oxazolidine-Based Compounds Using 1H NMR Spectroscopy

2010 ◽  
Vol 99 (8) ◽  
pp. 3362-3371 ◽  
Author(s):  
Gerard P. Moloney ◽  
Magdy N. Iskander ◽  
David J. Craik
Keyword(s):  
Nmr Spectroscopy ◽  
1H Nmr ◽  
1H Nmr Spectroscopy ◽  
Stability Studies

Evidence for cross-linking in tomato cutin using HR-MAS NMR spectroscopy

2003 ◽  
Vol 64 (6) ◽  
pp. 1163-1170 ◽  
Author(s):  
Ashish P. Deshmukh ◽  
André J. Simpson ◽  
Patrick G. Hatcher
Keyword(s):  
Nmr Spectroscopy ◽  
Mas Nmr ◽  
Cross Linking

Chemical Cross-Linking Gelatin with Natural Phenolic Compounds as Studied by High-Resolution NMR Spectroscopy

2010 ◽  
Vol 11 (4) ◽  
pp. 1125-1132 ◽  
Author(s):  
Xiaoqing Zhang ◽  
My Dieu Do ◽  
Philip Casey ◽  
Adrian Sulistio ◽  
Greg G. Qiao ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Nmr Spectroscopy ◽  
High Resolution ◽  
Cross Linking ◽  
High Resolution Nmr ◽  
Natural Phenolic Compounds ◽  
Chemical Cross Linking

scholarly journals 17O NMR spectroscopy-assisted in vitro bioactivity studies of the intermediates formed via Na2S and RSNO cross-linking reactions

RSC Advances ◽  
2020 ◽  
Vol 10 (65) ◽  
pp. 39617-39626
Author(s):  
Xingyu Zhu ◽  
Yin Gao
Keyword(s):  
Cell Culture ◽  
Nmr Spectroscopy ◽  
Cross Linking ◽  
In Vitro Bioactivity ◽  
17O Nmr ◽  
17O Nmr Spectroscopy

By using UV-Vis, 15N NMR and 17O NMR spectroscopy techniques, we characterized the intermediates (SSNO− and SNO−) obtained from RSNO and Na2S cross-linking reaction. We found that SSNO− could serve as NO reservoir in cell culture experiments.

DEVELOPMENT AND CHARACTERIZATION OF GASTRO RETENTIVE MUCOADHESIVE MICROBEADS CONTAINING SIMVASTATIN WITH DIFFERENT CROSS LINKING AGENTS

2020 ◽  
pp. 118-126
Author(s):  
VENKATA RAMANA REDDY K. ◽  
NAGABHUSHANAM M. V. ◽  
PAMULA REDDY B. ◽  
RAVINDAR NAIK E.
Keyword(s):  
Drug Release ◽  
Release Kinetics ◽  
Drug Loading ◽  
Aluminium Chloride ◽  
In Vitro Dissolution ◽  
Cross Linking ◽  
Stability Studies ◽  
Study Results ◽  
Curing Agents

Objective: The aim of the present work was to prepare and examine drug release of the oral controlled release microbeads using different curing agents by emulsification internal ionic gelation technique. Methods: Cross-linked alginate microbeads were prepared with different cross linking agents by using mucoadhesive properties. The formation and compatibility of microbeads were confirmed by compatibility studies. Prepared microbeads evaluated for encapsulated efficiency, micromeritic properties, drug loading, in vitro wash off studies, in vitro dissolution studies, drug release kinetics and stability studies Results: The in vitro drug release was influenced by both type of curing agents and type of polymers and no significant changes in characterization parameters was observed after 3 mo stability studies. The sustained release profile of optimized batch was found to be 99.66±0.18% in comparison to pure drug profile of 28.64±0.02% at 12 h release study. Results of both wash-off and in vitro studies suggests that batch (SF2) prepared with aluminium chloride has shown better mucoadhesive property. Drug release of optimized batch follows zero order with non fickian mechanism according to Korsmeyer-Peppas equation. Conclusion: The data suggest the use of simvastatin mucoadhesive cross linked microbeads to offer the potential for oral controlled drug delivery with improved gastric retention and capable to provide sustained drug release by using cross linking agents.

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