scholarly journals Contributions of the international plant science community to the fight against infectious diseases in humans – part 2: affordable drugs in edible plants for endemic and re‐emerging diseases

2021 ◽  
Author(s):  
Wenshu He ◽  
Can Baysal ◽  
Maria Lobato Gómez ◽  
Xin Huang ◽  
Derry Alvarez ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Emerging Diseases ◽  
Plant Science ◽  
Edible Plants ◽  
Science Community ◽  
International Plant

scholarly journals A modular cloning toolkit for genome editing in plants

2019 ◽  
Author(s):  
Florian Hahn ◽  
Andrey Korolev ◽  
Laura Sanjurjo Loures ◽  
Vladimir Nekrasov
Keyword(s):  
Genome Editing ◽  
Higher Order ◽  
Plant Science ◽  
Golden Gate ◽  
Coding Sequences ◽  
Guide Rna ◽  
Guide Rnas ◽  
Science Community ◽  
Modular Cloning ◽  
Multiple Expression

AbstractBackgroundCRISPR/Cas has recently become a widely used genome editing tool in various organisms, including plants. Applying CRISPR/Cas often requires delivering multiple expression units into plant and hence there is a need for a quick and easy cloning procedure. The modular cloning (MoClo), based on the Golden Gate (GG) method, has enabled development of cloning systems with standardised genetic parts, e.g. promoters, coding sequences or terminators, that can be easily interchanged and assembled into expression units, which in their own turn can be further assembled into higher order multigene constructs.ResultsHere we present an expanded cloning toolkit that contains ninety-nine modules encoding a variety of CRISPR/Cas-based nucleases and their corresponding guide RNA backbones. Among other components, the toolkit includes a number of promoters that allow expression of CRISPR/Cas nucleases (or any other coding sequences) and their guide RNAs in monocots and dicots. As part of the toolkit, we present a set of modules that enable quick and facile assembly of tRNA-sgRNA polycistronic units without a PCR step involved. We also demonstrate that our tRNA-sgRNA system is functional in wheat protoplasts.ConclusionsWe believe the presented CRISPR/Cas toolkit is a great resource that will contribute towards wider adoption of the CRISPR/Cas genome editing technology and modular cloning by researchers across the plant science community.

scholarly journals Emerging diseases in Chiroptera: why bats?

2010 ◽  
Vol 6 (4) ◽  
pp. 438-440 ◽  
Author(s):  
Gudrun Wibbelt ◽  
Marianne S. Moore ◽  
Tony Schountz ◽  
Christian C. Voigt
Keyword(s):  
Infectious Diseases ◽  
Human Health ◽  
North American ◽  
Emerging Diseases ◽  
Viral Diseases ◽  
Health Issues ◽  
Associated Diseases ◽  
White Nose Syndrome ◽  
First Time

A conference entitled ‘2nd International Berlin Bat Meeting: Bat Biology and Infectious Diseases’ was held between the 19 and 21 of February 2010 in Berlin, Germany. Researchers from two major disciplines, bat biologists and disease specialists, met for the first time in an interdisciplinary event to share their knowledge about bat-associated diseases. The focus of the meeting was to understand why in particular bats are the hosts of so many of the most virulent diseases globally. During several sessions, key note speakers and participants discussed infectious diseases associated with bats, including viral diseases caused by Henipa-, Filo-, Corona- and Lyssaviruses, the spread of white-nose syndrome in North American bats, bat immunology/immunogenetics, bat parasites, and finally, conservation and human health issues.

scholarly journals Ethical Dilemmas in Protecting Individual Rights versus Public Protection in the Case of Infectious Diseases

2013 ◽  
Vol 6 ◽  
pp. IDRT.S11205 ◽  
Author(s):  
Kai-Lit Phua
Keyword(s):  
Infectious Diseases ◽  
Ethical Issues ◽  
Ethical Dilemmas ◽  
Nipah Virus ◽  
Hemorrhagic Fever ◽  
Emerging Diseases ◽  
Public Health Approach ◽  
The Public ◽  
Contemporary World ◽  
Ebola Hemorrhagic Fever

Infectious diseases—including emerging and re-emerging diseases such as Ebola and tuberculosis—continue to be important causes of morbidity and mortality in the globalizing, contemporary world. This article discusses the ethical issues associated with protecting the rights of individuals versus the protection of the health of populations in the case of infectious diseases. The discussion uses the traditional medical ethics approach together with the public health approach presented by Faden and Shebaya. 3 Infectious diseases such as Ebola hemorrhagic fever, Nipah virus and HIV/AIDS (together with tuberculosis) will be used to illustrate particular points in the discussion.

scholarly journals Emerging and Re-emerging Vector-Borne Infectious Diseases and the Challenges for Control: A Review

2021 ◽  
Vol 9 ◽  
Author(s):  
Bayissa Chala ◽  
Feyissa Hamde
Keyword(s):  
Infectious Diseases ◽  
Public Health Problem ◽  
Hemorrhagic Fever ◽  
Emerging Diseases ◽  
West Nile Fever ◽  
Valley Fever ◽  
Vector Borne Diseases ◽  
Vector Borne ◽  
The Many ◽  
Epidemiological Profile

Vector-borne emerging and re-emerging diseases pose considerable public health problem worldwide. Some of these diseases are emerging and/or re-emerging at increasing rates and appeared in new regions in the past two decades. Studies emphasized that the interactions among pathogens, hosts, and the environment play a key role for the emergence or re-emergence of these diseases. Furthermore, social and demographic factors such as human population growth, urbanization, globalization, trade exchange and travel and close interactions with livestock have significantly been linked with the emergence and/or re-emergence of vector-borne diseases. Other studies emphasize the ongoing evolution of pathogens, proliferation of reservoir populations, and antimicrobial drug use to be the principal exacerbating forces for emergence and re-emergence of vector-borne infectious diseases. Still other studies equivocally claim that climate change has been associated with appearance and resurgence of vector-borne infectious diseases. Despite the fact that many important emerging and re-emerging vector-borne infectious diseases are becoming better controlled, our success in stopping the many new appearing and resurging vector-borne infectious diseases that may happen in the future seems to be uncertain. Hence, this paper reviews and synthesizes the existing literature to explore global patterns of emerging and re-emerging vector-borne infections and the challenges for their control. It also attempts to give insights to the epidemiological profile of major vector-borne diseases including Zika fever, dengue, West Nile fever, Crimean-Congo hemorrhagic fever, Chikungunya, Yellow fever, and Rift Valley fever.

scholarly journals Building a pathway for diversity in plant sciences in Argentina: highlighting the work of women scientists through virtual activities

2020 ◽  
Author(s):  
Gabriela Alejandra Auge ◽  
María José de Leone ◽  
Rocío Deanna ◽  
Sonia Oliferuk ◽  
Pamela Anahí Ribone ◽  
...  
Keyword(s):  
Plant Science ◽  
Extension Programs ◽  
Diverse Range ◽  
Diverse Workforce ◽  
The Social ◽  
Wide Range ◽  
Scientific Poster ◽  
Science Community ◽  
Plant Sciences ◽  
Experimental Approaches

AbstractEncouraging the participation of a diverse workforce in academia increases plurality as it broadens the range of skills, ways of thinking and experiences. Institutions and professional societies have been putting efforts on building plans that help make workplaces, conferences, education and extension programs more relatable to a highly diverse population. Argentina has an overall gender-balanced workforce in the sciences (~53% women/total), with an even higher representation in disciplines related to plant sciences. However, media outlets and national conferences related to genetics, botany, plant physiology, ecology and molecular biology, fail to reflect those numbers as the proportion of women invited for interviews, plenary lectures, and symposia falls below ~30%. As a way to increase the visibility of the wealth of plant science topics and experimental approaches in which Argentinian women work, and to facilitate connections among them across the country and abroad, we created the Argentinian Women in Plant Science network (https://argplantwomen.weebly.com/). This group has grown to over 200 members, representing a wide range of career stages and research topics. Since April, and taking advantage of the confinement situation, our weekly webinar series highlighting women plant scientists has reached an average audience of 60-70 participants, with a record of 100. Recently, we have begun a series of open professional development webinars to reach a wider public. Our first webinar, focused on Scientific poster design, had ~250 participants, most of them undergrad and graduate students from all over the country covering a diverse range of disciplines, including the social sciences. Even though we have immersed ourselves in the plant science community with our weekly seminars, we have expanded our goals with activities aimed to reach out to a much wider audience with webinars and teacher training workshops, hopefully making plant science more attainable to all.

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