A toolkit forNannochloropsis oceanicaCCMP1779 enables gene stacking and genetic engineering of the eicosapentaenoic acid pathway for enhanced long-chain polyunsaturated fatty acid production

Eric Poliner; Jane A. Pulman; Krzysztof Zienkiewicz; Kevin Childs; Christoph Benning; Eva M. Farré

doi:10.1111/pbi.12772

A toolkit forNannochloropsis oceanicaCCMP1779 enables gene stacking and genetic engineering of the eicosapentaenoic acid pathway for enhanced long-chain polyunsaturated fatty acid production

Plant Biotechnology Journal ◽

10.1111/pbi.12772 ◽

2017 ◽

Vol 16 (1) ◽

pp. 298-309 ◽

Cited By ~ 42

Author(s):

Eric Poliner ◽

Jane A. Pulman ◽

Krzysztof Zienkiewicz ◽

Kevin Childs ◽

Christoph Benning ◽

...

Keyword(s):

Fatty Acid ◽

Genetic Engineering ◽

Eicosapentaenoic Acid ◽

Polyunsaturated Fatty Acid ◽

Acid Production ◽

Chain Polyunsaturated Fatty Acid ◽

Gene Stacking ◽

Fatty Acid Production ◽

Acid Pathway ◽

Long Chain

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Long chain polyunsaturated fatty acid production and partitioning to triacylglycerols in four microalgae

Phytochemistry ◽

10.1016/s0031-9422(02)00201-7 ◽

2002 ◽

Vol 61 (1) ◽

pp. 15-24 ◽

Cited By ~ 182

Author(s):

Thierry Tonon ◽

David Harvey ◽

Tony R. Larson ◽

Ian A. Graham

Keyword(s):

Fatty Acid ◽

Polyunsaturated Fatty Acid ◽

Acid Production ◽

Chain Polyunsaturated Fatty Acid ◽

Fatty Acid Production ◽

Long Chain

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Co-expressing Eranthis hyemalis Lysophosphatidic acid acyltranferase 2 and elongase improves two very long chain polyunsaturated fatty acid production in Brassica carinata

Metabolic Engineering Communications ◽

10.1016/j.mec.2021.e00171 ◽

2021 ◽

pp. e00171

Author(s):

Dauenpen Meesapyodsuk ◽

Yi Chen ◽

Shengjian Ye ◽

Robert G. Chapman ◽

Xiao Qiu

Keyword(s):

Fatty Acid ◽

Polyunsaturated Fatty Acid ◽

Lysophosphatidic Acid ◽

Acid Production ◽

Brassica Carinata ◽

Chain Polyunsaturated Fatty Acid ◽

Fatty Acid Production ◽

Long Chain

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Climate warming is predicted to reduce omega-3, long-chain, polyunsaturated fatty acid production in phytoplankton

Global Change Biology ◽

10.1111/gcb.13295 ◽

2016 ◽

Vol 22 (8) ◽

pp. 2744-2755 ◽

Cited By ~ 75

Author(s):

Stefanie M. Hixson ◽

Michael T. Arts

Keyword(s):

Fatty Acid ◽

Polyunsaturated Fatty Acid ◽

Climate Warming ◽

Acid Production ◽

Chain Polyunsaturated Fatty Acid ◽

Omega 3 ◽

Fatty Acid Production ◽

Long Chain

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Metabolic Engineering of ω3-Very Long Chain Polyunsaturated Fatty Acid Production by an Exclusively Acyl-CoA-dependent Pathway

Journal of Biological Chemistry ◽

10.1074/jbc.m802377200 ◽

2008 ◽

Vol 283 (33) ◽

pp. 22352-22362 ◽

Cited By ~ 77

Author(s):

Mareike Hoffmann ◽

Martin Wagner ◽

Amine Abbadi ◽

Martin Fulda ◽

Ivo Feussner

Keyword(s):

Fatty Acid ◽

Metabolic Engineering ◽

Polyunsaturated Fatty Acid ◽

Acid Production ◽

Chain Polyunsaturated Fatty Acid ◽

Fatty Acid Production ◽

Dependent Pathway ◽

Long Chain

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Long-chain n — 3 polyunsaturated fatty acid production by members of the marine protistan group the thraustochytrids: screening of isolates and optimisation of docosahexaenoic acid production

Progress in Industrial Microbiology - Marine Bioprocess Engineering, Proceedings of an International Symposium organized under auspices of The Working Party on Applied Biocatalysis of the Eurpean Federation of Biotechnology and The European Society for Marine Biotechnology ◽

10.1016/s0079-6352(99)80112-x ◽

1999 ◽

pp. 193-202 ◽

Cited By ~ 3

Author(s):

R.D. Bowles ◽

A.E Hunt ◽

G.B Bremer ◽

M.G. Duchars ◽

R.A. Eaton

Keyword(s):

Fatty Acid ◽

Docosahexaenoic Acid ◽

Polyunsaturated Fatty Acid ◽

Acid Production ◽

Fatty Acid Production ◽

Long Chain

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Triglyceride-lowering effect of n-3 long chain polyunsaturated fatty acid: Eicosapentaenoic acid vs. docosahexaenoic acid

Lipids ◽

10.1007/bf02562315 ◽

1999 ◽

Vol 34 (S1) ◽

pp. S269-S269 ◽

Cited By ~ 6

Author(s):

P. Weber

Keyword(s):

Fatty Acid ◽

Docosahexaenoic Acid ◽

Eicosapentaenoic Acid ◽

Polyunsaturated Fatty Acid ◽

Chain Polyunsaturated Fatty Acid ◽

Lowering Effect ◽

Long Chain

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ISOLATION OF THREE NOVEL LONG-CHAIN POLYUNSATURATED FATTY ACID Δ9-ELONGASES AND THE TRANSGENIC ASSEMBLY OF THE ENTIRE PAVLOVA SALINA DOCOSAHEXAENOIC ACID PATHWAY IN NICOTIANA BENTHAMIANA1

Journal of Phycology ◽

10.1111/j.1529-8817.2010.00870.x ◽

2010 ◽

Vol 46 (5) ◽

pp. 917-925 ◽

Cited By ~ 16

Author(s):

James R. Petrie ◽

Anne M. Mackenzie ◽

Pushkar Shrestha ◽

Qing Liu ◽

Dion F. Frampton ◽

...

Keyword(s):

Fatty Acid ◽

Docosahexaenoic Acid ◽

Polyunsaturated Fatty Acid ◽

Chain Polyunsaturated Fatty Acid ◽

Acid Pathway ◽

Long Chain

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The long chain polyunsaturated fatty acid, eicosapentaenoic acid, induces caspase 3 mediated apoptosis in the adenocarcinoma cell line HT29 by a glutathione dependent mechanism

Gastroenterology ◽

10.1016/s0016-5085(00)84332-2 ◽

2000 ◽

Vol 118 (4) ◽

pp. A550

Author(s):

Elizabeth K. Lund ◽

Peter Latham ◽

Ian T. Johnson

Keyword(s):

Fatty Acid ◽

Eicosapentaenoic Acid ◽

Cell Line ◽

Polyunsaturated Fatty Acid ◽

Caspase 3 ◽

Chain Polyunsaturated Fatty Acid ◽

Adenocarcinoma Cell Line ◽

Adenocarcinoma Cell ◽

Long Chain ◽

Dependent Mechanism

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A 31-phosphorus neurospectroscopy study of ω-3 long-chain polyunsaturated fatty acid intervention with eicosapentaenoic acid and docosahexaenoic acid in patients with chronic refractory epilepsy

Prostaglandins Leukotrienes and Essential Fatty Acids ◽

10.1016/j.plefa.2007.07.004 ◽

2007 ◽

Vol 77 (2) ◽

pp. 105-107 ◽

Cited By ~ 12

Author(s):

B.K. Puri ◽

M.J. Koepp ◽

J. Holmes ◽

G. Hamilton ◽

A.W.C. Yuen

Keyword(s):

Fatty Acid ◽

Docosahexaenoic Acid ◽

Eicosapentaenoic Acid ◽

Polyunsaturated Fatty Acid ◽

Refractory Epilepsy ◽

Chain Polyunsaturated Fatty Acid ◽

Long Chain

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Long-chain n−3 polyunsaturated fatty acid production by members of the marine protistan group the thraustochytrids: screening of isolates and optimisation of docosahexaenoic acid production

Journal of Biotechnology ◽

10.1016/s0168-1656(99)00072-3 ◽

1999 ◽

Vol 70 (1-3) ◽

pp. 193-202 ◽

Cited By ~ 73

Author(s):

R.D Bowles ◽

A.E Hunt ◽

G.B Bremer ◽

M.G Duchars ◽

R.A Eaton

Keyword(s):

Fatty Acid ◽

Docosahexaenoic Acid ◽

Polyunsaturated Fatty Acid ◽

Acid Production ◽

Fatty Acid Production ◽

Long Chain

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