scholarly journals Oral immunotherapy with transgenic rice seed containing destructed Japanese cedar pollen allergens, Cry j 1 and Cry j 2, against Japanese cedar pollinosis

2012 ◽  
Vol 11 (1) ◽  
pp. 66-76 ◽  
Author(s):  
Yuhya Wakasa ◽  
Hidenori Takagi ◽  
Sakiko Hirose ◽  
Lijun Yang ◽  
Mayumi Saeki ◽  
...  
Keyword(s):  
Transgenic Rice ◽  
Japanese Cedar ◽  
Oral Immunotherapy ◽  
Rice Seed ◽  
Pollen Allergens ◽  
Japanese Cedar Pollen ◽  
Japanese Cedar Pollinosis ◽  
Cedar Pollen ◽  
Transgenic Rice Seed ◽  
Cry J 2

Preclinical evaluation of an immunotherapeutic peptide comprising 7 T-cell determinants of Cry j 1 and Cry j 2, the major Japanese cedar pollen allergens

2001 ◽  
Vol 108 (1) ◽  
pp. 94-100 ◽  
Author(s):  
Kazuki Hirahara ◽  
Toru Tatsuta ◽  
Toshiro Takatori ◽  
Masahiko Ohtsuki ◽  
Hideyo Kirinaka ◽  
...  
Keyword(s):  
T Cell ◽  
Japanese Cedar ◽  
Pollen Allergens ◽  
Preclinical Evaluation ◽  
Japanese Cedar Pollen ◽  
Cedar Pollen ◽  
Cry J 2

scholarly journals Seroprevalence of Immunoglobulin E Antibodies against Japanese Cedar Pollen Allergens Cry j 1 and Cry j 2 in Dogs Bred in Japan

2018 ◽  
Vol 5 (3) ◽  
pp. 79 ◽  
Author(s):  
Takashi Kuribayashi ◽  
Davide Cossu ◽  
Eiichi Momotani
Keyword(s):  
Immunoglobulin E ◽  
Japanese Cedar ◽  
Serum Levels ◽  
Enzyme Linked Immunosorbent Assay ◽  
Pollen Allergens ◽  
Kanagawa Prefecture ◽  
Japanese Cedar Pollen ◽  
Hyogo Prefecture ◽  
Cedar Pollen ◽  
Cry J 2

Levels of Japanese cedar pollen (Cryptomeria japonica) have increased in Japan and cedar pollinosis caused by Japanese cedar pollen has been reported in dogs. Serum levels of immunoglobulin E (IgE) against Cry j 1 and Cry j 2 in dogs raised in institutes and treated at veterinary hospitals in Japan were thus investigated. A total of 71 sera obtained from two institutes and 87 sera obtained from veterinary hospitals in the Hyogo and Kanagawa Prefectures were analyzed in this study. Serum levels of IgE were measured using the enzyme-linked immunosorbent assay with commercial purified Cry j 1 and Cry j 2. IgE against Cry j 1 and Cry j 2 in sera obtained from the two institutes were detected, despite the dogs being bred in enclosed areas. Moreover, significant differences were noted in the serum levels of IgE against Cry j 1 and Cry j 2 between the two institutes. The number of samples showing Cry j 1 or Cry j 2 levels above the cut-off values was greater in the Kanagawa Prefecture than in the Hyogo Prefecture. In total, 14 dogs showed Cry j 1 and Cry j 2 levels greater than the cut-off values in the Hyogo Prefecture, and only three such dogs were seen in the Kanagawa Prefecture. A significant correlation between serum levels against both allergens was observed (r2 = 0.6931, p < 0.0001).

scholarly journals T‐cell activation by transgenic rice seeds expressing the genetically modified Japanese cedar pollen allergens

Immunology ◽  
2019 ◽  
Vol 158 (2) ◽  
pp. 94-103
Author(s):  
Shinya Takaishi ◽  
Saburo Saito ◽  
Tomonori Endo ◽  
Daiya Asaka ◽  
Yuhya Wakasa ◽  
...  
Keyword(s):  
T Cell ◽  
Transgenic Rice ◽  
T Cell Activation ◽  
Cell Activation ◽  
Genetically Modified ◽  
Japanese Cedar ◽  
Pollen Allergens ◽  
Japanese Cedar Pollen ◽  
Rice Seeds ◽  
Cedar Pollen
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