Comparative analysis of the corneal birefringence pattern in healthy children and adults

Author(s):  
Marcelina Sobczak ◽  
Magdalena Asejczyk ◽  
Kamil Kalinowski ◽  
Barbara Pierścionek

The article presents the results of a sociological study, the purpose of which was to conduct a comparative analysis of the lifestyle and medical activity of children with diabetes mellitus and healthy children aged three to six years according to sociological surveys of their parents. The data was collected using a specially designed questionnaire consisting of 36 questions. The study was conducted in 2019 in children's polyclinics in Khabarovsk, Komsomolsk-on-Amur, Birobidzhan. The study involved 84 people. The results of the study were analyzed using relative and average values. Significant differences in the lifestyle and medical activity of families with children with diabetes mellitus and healthy children were revealed.


2019 ◽  
Vol 19 (1-2) ◽  
pp. 95-100
Author(s):  
V. V Dul’nev ◽  
L. A Avrasina

Introducion. Children with cerebral palsy demonstrate high prevalence of the cognitive impairment (CI). One of the key components of CI pathogenesis is sensory disafferentation. Aim. The goal of this investigation is to perform comparative analysis of event-related potentials (ERP) in children with CP and in healthy children. Materials and methods. A total of 30 children with CP (mean age 8.9 ± 0.84 year) and 44 healthy subjects (mean age 9.5 ± 0.60 years) were observed. Registration and comparative analysis of the acoustic ERP were performed with the use of non-parametric tests. Results. The decrease in age-related ERP latencies was slower in the main group. Significant elongation of ERP latencies was also observed in the main group, despite the clinical absence of cognitive decline. Conclusions. Our findings confirm the theory of sensory information cortical processing delay in children with CP. More investigations should be performed for the assessment of reliability of the ERP in the objective evaluation of CI level.


World Science ◽  
2018 ◽  
Vol 1 (10(38)) ◽  
pp. 25-27
Author(s):  
Nadjimutdinova N. Sh. ◽  
Amonov Sh. E. ◽  
Alieva M. U.

Objective: make a comparative analysis of the voice of the index (VHI) and endoscopic studies in the pathology of the voice of children.Material and Methods: The study involved 87 children, from 6 months to 14 years. The clinical study included fibrorinolaryngoscopy with video fixation (C-MAC, K. Storz, Ø-2,7 mm) and a survey of parents (or guardians) of children at the Uzbek version of the voice handicap index (pVHI), with sub- sections (functional - F, the physical - P and emotional - E).Results: endoscopic diagnosed laryngitis 20,6% (n = 18), functional 16,1% (n = 14) and mutational 9,2% (n = 8), dysphonia, benign larynx (respiratory papillamatosis) - 18.4 % (n = 16), the vocal cords paresis - 5.7% (n = 5), the vocal folds nodules 26.4% (n = 23), throat structure anomalies (acquired) 3,4% (n = 3). The survey revealed pVHI average points total pVHI and its sub-group of patients were as follows: F - 13,94, P - 15.48, E - 12.15 and T - 41.58, which is significantly higher than the group of healthy children and children with functional disorders of voice.Conclusions: Fibrolaryngoscopy with the smallest diameter of the lumen of the laryngoscope with video fixation allowed to quickly ascertain the diagnosis of organic disease of the larynx in children. In addition, the survey pVHI allowed to differentiate the severity of the vocal apparatus, to conduct timely special endoscopic diagnosis of vocal cord diseases.


2021 ◽  
Vol 14 (1) ◽  
pp. 65-68
Author(s):  
L. S. Khamraeva ◽  
L. Yu. Bobokha ◽  
L. A. Katargina

Purpose. To determine the specificity of functional and tonographic parameters of the eyeball in children with cataract, aphakia and pseudophakia. Material and methods. A comparative analysis of eye hydrodynamics indices was made according to a simplified procedure, using the Friedenwald nomogram, on 75 children aged 2 to 17 years with cataract (24 eyes), aphakia (21 eyes), pseudophakia (15 eyes), and IOL dislocation (15 eyes), as well as 12 healthy children.Results. In pseudophakia, true IOP was found to fall to 10.00 ± 0.01 mm Hg due to a decrease in aqueous humor production (to 0.10±0.01 mm3 / min) and increase of its outflow (to 0.75 ± 0.02 mm3/min / mm). IOL dislocation led to an increase in true IOP (24.40±1.0 mm Hg) due to an increase in aqueous humor production (4.09±0.05 mm3/min) and a decrease in its outflow (0.010 ± 0.002 mm3/min/mm). In these eyes, clinical manifestations of secondary pseudophakic glaucoma were noted, which are explained by factors obstructing aqueous humor outflow (vitreous prolapse and partial vitreous block) and considered an indication for re-operation.Conclusion. Statistically significant changes of hydrodynamic eye parameters in children with pseudophakia have been detected: increased true IOP in IOL dislocation, and, conversely, reduced true IOP in case of the normal IOL location. The authors believe that eye “hypotension” in case of pseudophakia requires further study.


2017 ◽  
Vol 98 (5) ◽  
pp. 704-708
Author(s):  
G A Akhmedov

Aim. To perform comparative analysis of DQB1 and DQA1 class II genes of the human leukocyte antigen (HLA) system in the population of Azerbaijan. Methods. We studied the alleles of HLA DQ gene and subtypes of HLA DRB1*04 in 160 children with diabetes mellitus and in 271 healthy children from the population of Azerbaijan. Out of 160 patients, 50.6% (n=81) were boys, 49.4% (n=79) were girls. All patients with diabetes were under the age of 18 years. As a control group, 271 students of the Medical College No. 1 were involved: 79 (29.1%) boys, 192 (70.9%) girls. The collected blood samples were sent for further investigation to the medical genetic laboratory where polymerase chain reaction-based genotyping of the samples was performed. Results. For the first time, the relationship of diabetes with class II genes of the HLA system was studied. The Azerbaijani were found to have higher risk associated with HLA DQ2 molecule. The molecule HLA DQ8 also increases risk, although it is lower in comparison with HLA DQ2 molecule. What is unusual is that for this population the allele HLA DQB1*0304 was also associated with the risk of diabetes. Conclusion. The haplotype DQB1*0302-DQA1*03/DQB1*02-DQA1*05 (DQ8/DQ2.5) associated with high risk of diabetes is found in 3% of the representatives of the population of Azerbaijan, which is estimated as the average prevalence of diabetes.


2020 ◽  
Vol 14 (11) ◽  
pp. e0008769
Author(s):  
Vinay Modgil ◽  
Jaspreet Mahindroo ◽  
Chandradeo Narayan ◽  
Manmohit Kalia ◽  
Md Yousuf ◽  
...  

Enteroaggregative Escherichia coli (EAEC) is an evolving enteric pathogen that causes acute and chronic diarrhea in developed and industrialized nations in children. EAEC epidemiology and the importance of atypical EAEC (aEAEC) isolation in childhood diarrhea are not well documented in the Indian setting. A comparative analysis was undertaken to evaluate virulence, phylogeny, and antibiotic sensitivity among typical tEAEC versus aEAEC. A total of 171 EAEC isolates were extracted from a broad surveillance sample of diarrheal (N = 1210) and healthy children (N = 550) across North India. Polymerase chain reaction (PCR) for the aggR gene (master regulator gene) was conducted to differentiate tEAEC and aEAEC. For 21 virulence genes, we used multiplex PCR to classify possible virulence factors among these strains. Phylogenetic classes were identified by a multiplex PCR for chuA, yjaA, and a cryptic DNA fragment, TspE4C2. Antibiotic susceptibility was conducted by the disc diffusion method as per CLSI guidelines. EAEC was associated with moderate to severe diarrhea in children. The prevalence of EAEC infection (11.4%) was higher than any other DEC group (p = 0.002). tEAEC occurrence in the diarrheal group was higher than in the control group (p = 0.0001). tEAEC strain harbored more virulence genes than aEAEC. astA, aap, and aggR genes were most frequently found in the EAEC from the diarrheal population. Within tEAEC, this gene combination was present in more than 50% of strains. Also, 75.8% of EAEC strains were multidrug-resistant (MDR). Phylogroup D (43.9%) and B1 (39.4%) were most prevalent in the diarrheal and control group, respectively. Genetic analysis revealed EAEC variability; the comparison of tEAEC and aEAEC allowed us to better understand the EAEC virulence repertoire. Further microbiological and epidemiological research is required to examine the pathogenicity of not only typical but also atypical EAEC.


2018 ◽  
Vol 17 (3) ◽  
pp. 254-258 ◽  
Author(s):  
Rita R. Kil’diyarova

Preventive medical examinations of healthy children or mass prophylactic examinations of minors in the Russian Federation are governed by the orders of the Ministry of Health of Russia. The data on regulatory and organizational support for the prophylactic examination of healthy children is presented. The article provides a comparative analysis on the frequency of children examinations by a district pediatrician, consultations by specialty doctors as well as additional examinations in accordance with the orders of the Ministry of Health of Russia No.1346n and No.514n entered into force on January 1, 2018. The authors give comments on the proposals of MO Revnova et al. suggested in the article “Towards the Improvement of the System of Mass Prophylactic Examinations of the Child Population”.


2017 ◽  
Vol 6 (2) ◽  
pp. 50-63
Author(s):  
T.G. Goryacheva ◽  
L. Shal ◽  
S. Rikhter

This article is devoted to the study of memory features for children of primary school age with perinatal central nervous system lesions in history, in particular, hypoxia. These results were compared with those obtained in a study of healthy peers. The study involved 32 children aged 6 to 8, of which 16 children had a o perinatal hypoxia in history and 16 without CNS perinatal pathology. Based on these results, it was found that children who have suffered hypoxia have a lower playback volume and productivity modal-specific forms of memory, which are subject to greater influence of interfering effects than that of healthy children.


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