N/P imbalance as a key driver for the invasion of oligotrophic dune systems by a woody legume

Florian Ulm; Christine Hellmann; Cristina Cruz; Cristina Máguas

doi:10.1111/oik.03810

N/P imbalance as a key driver for the invasion of oligotrophic dune systems by a woody legume

Oikos ◽

10.1111/oik.03810 ◽

2016 ◽

Vol 126 (2) ◽

Cited By ~ 12

Author(s):

Florian Ulm ◽

Christine Hellmann ◽

Cristina Cruz ◽

Cristina Máguas

Keyword(s):

Dune Systems ◽

Woody Legume ◽

Key Driver

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SGC-CK2-1: The First Selective Chemical Probe for the Pleiotropic Kinase CK2

10.26434/chemrxiv.12296180.v2 ◽

2020 ◽

Author(s):

Carrow Wells ◽

David Drewry ◽

Julie E. Pickett ◽

Alison D. Axtman

Keyword(s):

Cell Lines ◽

Small Molecule ◽

Chemical Probe ◽

High Quality ◽

Extensive Evaluation ◽

Key Driver ◽

Selective Chemical ◽

Kinase Ck2 ◽

Ck2 Inhibitors

Building upon a wealth of published knowledge surrounding the pyrazolopyrimidine scaffold, we designed a small library around the most selective small molecule CK2 inhibitors reported. Through extensive evaluation of this library we identified inhibitor 24 (SGC-CK2-1) as a potent, selective, and cell-active CK2 chemical probe. Remarkably, despite years of research pointing to CK2 as a key driver in cancer, our probe did not elicit an antiproliferative phenotype in cell lines tested. While many publications have attempted tocharacterize CK2 function, CK2 biology is complex and a high-quality chemical tool like SGC-CK2-1 will aid in connecting CK2 functions to phenotypes.

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WISATA BAHARI PADA ZONA PEMANFAATAN TAMAN NASIONAL MANUSELA: POTENSI DAN FAKTOR PENGARUH PENGEMBANGAN

PAPALELE (Jurnal Penelitian Sosial Ekonomi Perikanan dan Kelautan) ◽

10.30598/papalele.2018.2.2.66 ◽

2018 ◽

Vol 2 (2) ◽

pp. 66-73

Author(s):

Ivonne R. G. Kaya ◽

Fildo De Lima

Keyword(s):

National Park ◽

Point Of View ◽

Structured Interviews ◽

Factors Affecting ◽

Tourist Attractions ◽

Income Sources ◽

Economic Progress ◽

Key Driver ◽

Tourism Attractions ◽

Depth Interviews

Tourism has become one of the major players in ‎international commerce and represents one of the main income ‎sources for many developing countries at the same time. These dynamics have turned tourism into a key driver for socio-‎economic progress.‎ This article described the potential of tourism attraction and factor affecting the development of marine tourism area in the utilization zone of Manusela National Park. Semi-structured interviews, in-depth interviews and participant observations were conducted with respondent (n=110) in Bellarizky, Air Belanda, Ora Beach and Lizar Bahari resort. The potential of tourist attractions in the utilization zone of Manusela National Park is as a snorkeling, diving and point of view. Factors affecting the development are service, transportation, supporting facilities and tourism attractions.

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