Genes not Genomes Called Key Driver of Bacterial Diversity

2012 ◽  
Vol 7 (9) ◽  
pp. 386-387
Author(s):  
Marcia Stone
Keyword(s):  
Bacterial Diversity ◽  
Key Driver

Minimal and dynamic bacterial diversity in grease trap revealed by molecular analysis

2012 ◽  
Vol 43 (1) ◽  
pp. 29-41 ◽  
Author(s):  
Lucas F.S. ◽  
Richard F. ◽  
Adolphe Y. ◽  
Haenn S. ◽  
Moilleron R. ◽  
...  
Keyword(s):  
Bacterial Diversity ◽  
Molecular Analysis

SGC-CK2-1: The First Selective Chemical Probe for the Pleiotropic Kinase CK2

2020 ◽  
Author(s):  
Carrow Wells ◽  
David Drewry ◽  
Julie E. Pickett ◽  
Alison D. Axtman
Keyword(s):  
Cell Lines ◽  
Small Molecule ◽  
Chemical Probe ◽  
High Quality ◽  
Extensive Evaluation ◽  
Key Driver ◽  
Selective Chemical ◽  
Kinase Ck2 ◽  
Ck2 Inhibitors

Building upon a wealth of published knowledge surrounding the pyrazolopyrimidine scaffold, we designed a small library around the most selective small molecule CK2 inhibitors reported. Through extensive evaluation of this library we identified inhibitor 24 (SGC-CK2-1) as a potent, selective, and cell-active CK2 chemical probe. Remarkably, despite years of research pointing to CK2 as a key driver in cancer, our probe did not elicit an antiproliferative phenotype in cell lines tested. While many publications have attempted tocharacterize CK2 function, CK2 biology is complex and a high-quality chemical tool like SGC-CK2-1 will aid in connecting CK2 functions to phenotypes.

WISATA BAHARI PADA ZONA PEMANFAATAN TAMAN NASIONAL MANUSELA: POTENSI DAN FAKTOR PENGARUH PENGEMBANGAN

2018 ◽  
Vol 2 (2) ◽  
pp. 66-73
Author(s):  
Ivonne R. G. Kaya ◽  
Fildo De Lima
Keyword(s):  
National Park ◽  
Point Of View ◽  
Structured Interviews ◽  
Factors Affecting ◽  
Tourist Attractions ◽  
Income Sources ◽  
Economic Progress ◽  
Key Driver ◽  
Tourism Attractions ◽  
Depth Interviews

Tourism has become one of the major players in ‎international commerce and represents one of the main income ‎sources for many developing countries at the same time. These dynamics have turned tourism into a key driver for socio-‎economic progress.‎ This article described the potential of tourism attraction and factor affecting the development of marine tourism area in the utilization zone of Manusela National Park. Semi-structured interviews, in-depth interviews and participant observations were conducted with respondent (n=110) in Bellarizky, Air Belanda, Ora Beach and Lizar Bahari resort. The potential of tourist attractions in the utilization zone of Manusela National Park is as a snorkeling, diving and point of view. Factors affecting the development are service, transportation, supporting facilities and tourism attractions.

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