scholarly journals Insights from in vivo micro‐ CT analysis: testing the hydraulic vulnerability segmentation in Acer pseudoplatanus and Fagus sylvatica seedlings

2018 ◽  
Vol 221 (4) ◽  
pp. 1831-1842 ◽  
Author(s):  
Adriano Losso ◽  
Andreas Bär ◽  
Birgit Dämon ◽  
Christian Dullin ◽  
Andrea Ganthaler ◽  
...  
Keyword(s):  
Fagus Sylvatica ◽  
Acer Pseudoplatanus ◽  
Micro Ct ◽  
Hydraulic Vulnerability ◽  
Ct Analysis

Single‐staged implant placement using the bone ring technique with and without membrane placement: Micro‐CT analysis in a preclinical in vivo study

2019 ◽  
Vol 31 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Ken Nakahara ◽  
Maiko Haga‐Tsujimura ◽  
Kensuke Igarashi ◽  
Eizaburo Kobayashi ◽  
Benoit Schaller ◽  
...  
Keyword(s):  
In Vivo Study ◽  
Micro Ct ◽  
Implant Placement ◽  
Ct Analysis

scholarly journals Can implants move in bone? A longitudinal in vivo micro‐CT analysis of implants under constant forces in rat vertebrae

2019 ◽  
Vol 30 (12) ◽  
pp. 1179-1189
Author(s):  
Kathrin Becker ◽  
Frank Schwarz ◽  
Nicole Jasmin Rauch ◽  
Silava Khalaph ◽  
Ilja Mihatovic ◽  
...  
Keyword(s):  
Micro Ct ◽  
Ct Analysis

scholarly journals Distributional Variations in Trabecular Architecture of the Mandibular Bone: An In Vivo Micro-CT Analysis in Rats

PLoS ONE ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. e0116194 ◽  
Author(s):  
Zhongshuang Liu ◽  
Chengwei Yan ◽  
Chen kang ◽  
Bin Zhang ◽  
Ying Li
Keyword(s):  
Trabecular Architecture ◽  
Micro Ct ◽  
Mandibular Bone ◽  
Ct Analysis

scholarly journals Strontium Incorporated Coralline Hydroxyapatite for Engineering Bone

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Waiching Liu ◽  
Ting Wang ◽  
Yuhui Shen ◽  
Haobo Pan ◽  
Songlin Peng ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Rat Model ◽  
Bone Growth ◽  
Micro Ct ◽  
Coralline Hydroxyapatite ◽  
Ct Analysis ◽  
Surface Morphologies ◽  
Volume Retention

Goniopora was hydrothermally converted to coralline hydroxyapatite (CHA) and incorporated with Sr (Sr-CHA). The pore size of Goniopora was in the range of 40–300 μm with a porosity of about 68%. Surface morphologies of the coral were modified to flake-like hydroxyapatite structures on CHA and the addition of Sr detected on Sr-CHA as confirmed by SEM and EDX. As the first report of incorporating Sr into coral, about 6%–14% Sr was detected on Sr-CHA. The compressive strengths of CHA and Sr-CHA were not compromised due to the hydrothermal treatments. Sr-CHA was studied in vitro using MC3T3-E1 cells and in vivo with an ovariectomized rat model. The proliferation of MC3T3-E1 cells was significantly promoted by Sr-CHA as compared to CHA. Moreover, higher scaffold volume retention (+40%) was reported on the micro-CT analysis of the Sr-CHA scaffold. The results suggest that the incorporation of Sr in CHA can further enhance the osteoconductivity and osteoinductivity of corals. Strontium has been suggested to stimulate bone growth and inhibit bone resorption. In this study, we have successfully incorporated Sr into CHA with the natural porous structure remained and explored the idea of Sr-CHA as a potential scaffolding material for bone regeneration.

Constant Strain Rate and Peri-Implant Bone Modeling: An In Vivo Longitudinal Micro-CT Analysis

2011 ◽  
Vol 15 (3) ◽  
pp. 358-366 ◽  
Author(s):  
Els De Smet ◽  
Siegfried V. N. Jaecques ◽  
Martine Wevers ◽  
Jos Vander Sloten ◽  
Ignace E. Naert
Keyword(s):  
Strain Rate ◽  
Constant Strain Rate ◽  
Bone Modeling ◽  
Micro Ct ◽  
Ct Analysis

scholarly journals A micro-CT analysis of murine lung recruitment in bleomycin-induced lung injury

2008 ◽  
Vol 105 (2) ◽  
pp. 669-677 ◽  
Author(s):  
Scott Shofer ◽  
Cristian Badea ◽  
Yi Qi ◽  
Erin Potts ◽  
W. Michael Foster ◽  
...  
Keyword(s):  
Lung Injury ◽  
Lung Recruitment ◽  
Normal Lung ◽  
Micro Ct ◽  
Thoracic Imaging ◽  
Ct Analysis ◽  
High Resolution Images ◽  
X Ray Computed ◽  
Parenchymal Injury

The effects of lung injury on pulmonary recruitment are incompletely understood. X-ray computed tomography (CT) has been a valuable tool in assessing changes in recruitment during lung injury. With the development of preclinical CT scanners designed for thoracic imaging in rodents, it is possible to acquire high-resolution images during the evolution of a pulmonary injury in living mice. We quantitatively assessed changes in recruitment caused by intratracheal bleomycin at 1 and 3 wk after administration using micro-CT in 129S6/SvEvTac mice. Twenty female mice were administered 2.5 U of bleomycin or saline and imaged with micro-CT at end inspiration and end expiration. Mice were extubated and allowed to recover from anesthesia and then reevaluated in vivo for quasi-static compliance measurements, followed by harvesting of the lungs for collagen analysis and histology. CT images were converted to histograms and analyzed for mean lung attenuation (MLA). MLA was significantly greater for bleomycin-exposed mice at week 1 for both inspiration ( P < 0.0047) and exhalation ( P < 0.0377) but was not significantly different for week 3 bleomycin-exposed mice. However, week 3 bleomycin-exposed mice did display significant increases in MLA shift from expiration to inspiration compared with either group of control mice ( P < 0.005), suggesting increased lung recruitment at this time point. Week 1 bleomycin-exposed mice displayed normal shifts in MLA with inspiration, suggesting normal lung recruitment despite significant radiographic and histological changes. Lung alveolar recruitment is preserved in a mouse model of bleomycin-induced parenchymal injury despite significant changes in radiographic and physiological parameters.

scholarly journals The Influence of Electron Beam Sterilization on In Vivo Degradation of β-TCP/PCL of Different Composite Ratios for Bone Tissue Engineering

Micromachines ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 273 ◽  
Author(s):  
Jin-Ho Kang ◽  
Janelle Kaneda ◽  
Jae-Gon Jang ◽  
Kumaresan Sakthiabirami ◽  
Elaine Lui ◽  
...  
Keyword(s):  
Electron Beam ◽  
Volume Reduction ◽  
Micro Ct ◽  
Micro Computed Tomography ◽  
Average Volume ◽  
Volume Changes ◽  
Significant Difference ◽  
Ct Analysis ◽  
Time Point

We evaluated the effect of electron beam (E-beam) sterilization (25 kGy, ISO 11137) on the degradation of β-tricalcium phosphate/polycaprolactone (β-TCP/PCL) composite filaments of various ratios (0:100, 20:80, 40:60, and 60:40 TCP:PCL by mass) in a rat subcutaneous model for 24 weeks. Volumes of the samples before implantation and after explantation were measured using micro-computed tomography (micro-CT). The filament volume changes before sacrifice were also measured using a live micro-CT. In our micro-CT analyses, there was no significant difference in volume change between the E-beam treated groups and non-E-beam treated groups of the same β-TCP to PCL ratios, except for the 0% β-TCP group. However, the average volume reduction differences between the E-beam and non-E-beam groups in the same-ratio samples were 0.76% (0% TCP), 3.30% (20% TCP), 4.65% (40% TCP), and 3.67% (60% TCP). The E-beam samples generally had more volume reduction in all experimental groups. Therefore, E-beam treatment may accelerate degradation. In our live micro-CT analyses, most volume reduction arose in the first four weeks after implantation and slowed between 4 and 20 weeks in all groups. E-beam groups showed greater volume reduction at every time point, which is consistent with the results by micro-CT analysis. Histology results suggest the biocompatibility of TCP/PCL composite filaments.

scholarly journals Modelling the skeletal muscle injury recovery using in vivo contrast-enhanced micro-CT: a proof-of-concept study in a rat model

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Bruno Paun ◽  
Daniel García Leon ◽  
Alex Claveria Cabello ◽  
Roso Mares Pages ◽  
Elena de la Calle Vargas ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Rat Model ◽  
Muscle Injury ◽  
Micro Ct ◽  
Skeletal Muscle Injury ◽  
Monitoring Time ◽  
Contrast Enhanced Ct ◽  
Contrast Enhanced ◽  
Injury Recovery

Abstract Background Skeletal muscle injury characterisation during healing supports trauma prognosis. Given the potential interest of computed tomography (CT) in muscle diseases and lack of in vivo CT methodology to image skeletal muscle wound healing, we tracked skeletal muscle injury recovery using in vivo micro-CT in a rat model to obtain a predictive model. Methods Skeletal muscle injury was performed in 23 rats. Twenty animals were sorted into five groups to image lesion recovery at 2, 4, 7, 10, or 14 days after injury using contrast-enhanced micro-CT. Injury volumes were quantified using a semiautomatic image processing, and these values were used to build a prediction model. The remaining 3 rats were imaged at all monitoring time points as validation. Predictions were compared with Bland-Altman analysis. Results Optimal contrast agent dose was found to be 20 mL/kg injected at 400 μL/min. Injury volumes showed a decreasing tendency from day 0 (32.3 ± 12.0mm3, mean ± standard deviation) to day 2, 4, 7, 10, and 14 after injury (19.6 ± 12.6, 11.0 ± 6.7, 8.2 ± 7.7, 5.7 ± 3.9, and 4.5 ± 4.8 mm3, respectively). Groups with single monitoring time point did not yield significant differences with the validation group lesions. Further exponential model training with single follow-up data (R2 = 0.968) to predict injury recovery in the validation cohort gave a predictions root mean squared error of 6.8 ± 5.4 mm3. Further prediction analysis yielded a bias of 2.327. Conclusion Contrast-enhanced CT allowed in vivo tracking of skeletal muscle injury recovery in rat.

Micro‐CT analysis of the Lisfranc complex reveals higher bone mineral density in dorsal compared to plantar regions

2021 ◽  
Author(s):  
Melissa R. Requist ◽  
Yantarat Sripanich ◽  
Tim Rolvien ◽  
Amy L. Lenz ◽  
Alexej Barg
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Micro Ct ◽  
Mineral Density ◽  
Ct Analysis
Sign in / Sign up

Export Citation Format

Share Document