scholarly journals Relationships of abdominal pain, reports to visceral and temperature pain sensitivity, conditioned pain modulation, and heart rate variability in irritable bowel syndrome

2016 ◽  
Vol 28 (7) ◽  
pp. 1094-1103 ◽  
Author(s):  
M. E. Jarrett ◽  
C. J. Han ◽  
K. C. Cain ◽  
R. L. Burr ◽  
R. J. Shulman ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Irritable Bowel Syndrome ◽  
Abdominal Pain ◽  
Pain Sensitivity ◽  
Pain Modulation ◽  
Conditioned Pain Modulation ◽  
Pain Reports ◽  
Irritable Bowel

scholarly journals Conditioned Pain Modulation in Women With Irritable Bowel Syndrome

2014 ◽  
Vol 16 (4) ◽  
pp. 368-377 ◽  
Author(s):  
Monica E. Jarrett ◽  
Robert J. Shulman ◽  
Kevin C. Cain ◽  
Wimon Deechakawan ◽  
Lynne T. Smith ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Psychological Distress ◽  
Salivary Cortisol ◽  
Pain Sensitivity ◽  
Pain Modulation ◽  
Conditioned Pain Modulation ◽  
Somatic Pain ◽  
Before And After ◽  
Cortisol Levels ◽  
Irritable Bowel

Evidence suggests that patients with irritable bowel syndrome (IBS) are more vigilant to pain-associated stimuli. The aims of this study were to compare women with IBS ( n = 20) to healthy control (HC, n = 20) women on pain sensitivity, conditioned pain modulation (CPM) efficiency, and salivary cortisol levels before and after the CPM test and to examine the relationship of CPM efficiency with gastrointestinal pain, somatic pain, psychological distress symptoms, and salivary cortisol levels in each group. Women, aged 20–42 years, gave consent, completed questionnaires, and kept a symptom diary for 2 weeks. CPM efficiency was tested with a heat test stimulus and cold water condition stimulus in a laboratory between 8 and 10 a.m. on a follicular phase day. Salivary cortisol samples were collected just before and after the experimental testing. Compared to the HC group, women with IBS reported more days with gastrointestinal and somatic pain/discomfort, psychological distress, fatigue, and feeling stressed. During the CPM baseline testing, women with IBS reported greater pain sensitivity compared to the HC group. There was no significant group difference in salivary cortisol levels nor in CPM efficiency, though a post-hoc analysis showed a higher prevalence of impaired CPM efficiency among IBS subjects with more severe lower-GI symptoms. In the IBS group, reduced CPM efficiency was associated with daily abdominal pain/discomfort and psychological distress. Overall, women with IBS exhibited an increased sensitivity to thermal stimuli. Impaired CPM was present in a subset of women with IBS.

Comparison of Autonomic Nervous System Indices Based on Abdominal Pain Reports in Women with Irritable Bowel Syndrome

2000 ◽  
Vol 2 (2) ◽  
pp. 97-106 ◽  
Author(s):  
Robert L. Burr ◽  
Margaret Heitkemper ◽  
Monica Jarrett ◽  
Kevin C. Cain
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Irritable Bowel Syndrome ◽  
Abdominal Pain ◽  
Psychological Distress ◽  
Parasympathetic Nervous System ◽  
Severe Abdominal Pain ◽  
Important Symptom ◽  
Irritable Bowel

Abdominal pain is an important symptom in irritable bowel syndrome (IBS), but patients report typical pain intensities ranging from mild to very severe. In a sample of women, the authors sought to determine whether measures of systemic autonomic activity are related to self-reported pain intensity and the occurrence of pain in the postprandial period. One hundred and six women with IBS and 41 controls completed bowel symptom and psychological distress questionnaires and wore 24-h Holter electrocardiogram monitors to estimate global heart rate variability measures of parasympathetic activity and sympathetic nervous system/parasympathetic nervous system balance. About one-third of the IBS sample reported severe or very severe abdominal pain (n = 34/106), and about one-half of the IBS sample reported postprandial pain (n = 52/106). Even after statistically controlling for age, body mass index, and psychological distress, vagal heart rate variability measures were markedly lower in women reporting high pain (P < 0.01) and markedly higher in women reporting postprandial pain (P < 0.02). The vagal component of heart rate variability appears to be reduced in women with severe abdominal pain, especially in those whose pain is not postprandial.

scholarly journals Assessment of Autonomic Nerve Function In Patients With Irritable Bowel Syndrome

2012 ◽  
Vol 7 (1) ◽  
pp. 53-59
Author(s):  
Mohammad Nayem ◽  
Noorzahan Begum ◽  
Sultana Ferdousi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Irritable Bowel Syndrome ◽  
Autonomic Nerve ◽  
Total Power ◽  
Heart Rate Variability Analysis ◽  
Nerve Function ◽  
Autonomic Nerve Function ◽  
Irritable Bowel ◽  
Function Activity

Background: Autonomic nerve function impairment is related to development of Irritable Bowel Syndrome (IBS). Heart rate variability (HRV) is a useful tool to measure autonomic nerve function activity and also sympatho-vagal balance.Objective: To assess autonomic nerve function activity by heart rate variability analysis in patients with Irritable Bowel Syndrome.Methods: This cross sectional study was conducted in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from 1st July 2010 to 30th June 2011. Ninety patients aged 20-50 years of both sexes with Irritable bowel syndrome were included in the study group. They were enrolled from the OPD of Gastroenterology in BSMMU. For comparison age and sex matched 30 apparently healthy subjects were also studied as control. The power spectral HRV parameters were recorded by a digital Polyrite. For statistical analysis ANOVA, independent sample t-test were performed.Results: Mean resting pulse rate, mean HR, SBP, DBP, LF, LF norm and LF/HF were significantly higher(P<0.001) and total power, HF, HF norm were significantly lower(P<0.001) in IBS group compared to those of control.Conclusion: This study concludes markedly lower parasympathetic with concomitant higher sympathetic activity and shifting of sympathovagal balance towards sympathetic predominance in patients of IBS. DOI: http://dx.doi.org/10.3329/jbsp.v7i1.11163 J Bangladesh Soc Physiol. 2012, June; 7(1): 53-59

Systematic review with meta-analysis: conditioned pain modulation in patients with the irritable bowel syndrome

2018 ◽  
Vol 48 (8) ◽  
pp. 797-806 ◽  
Author(s):  
Ahmed Albusoda ◽  
James K. Ruffle ◽  
Kathrine A. Friis ◽  
Maximilian R. Gysan ◽  
Asbjørn M. Drewes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Irritable Bowel Syndrome ◽  
Meta Analysis ◽  
Pain Modulation ◽  
Conditioned Pain Modulation ◽  
Irritable Bowel

Heart rate variability characteristics of patients with irritable bowel syndrome and associations with symptoms

2018 ◽  
Vol 30 (7) ◽  
pp. e13320 ◽  
Author(s):  
A. Polster ◽  
P. Friberg ◽  
V. Gunterberg ◽  
L. Öhman ◽  
B. Le Nevé ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Irritable Bowel Syndrome ◽  
Irritable Bowel
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