Distensibility of the anal canal in patients with idiopathic fecal incontinence: a study with the Functional Lumen Imaging Probe

2013 ◽  
Vol 26 (2) ◽  
pp. 255-263 ◽  
Author(s):  
G. Sørensen ◽  
D. Liao ◽  
L. Lundby ◽  
L. Fynne ◽  
S. Buntzen ◽  
...  
Keyword(s):  
Fecal Incontinence ◽  
Anal Canal ◽  
Imaging Probe ◽  
Functional Lumen Imaging Probe ◽  
Idiopathic Fecal Incontinence

scholarly journals IDDF2018-ABS-0175 Functional lumen imaging probe assessment of anal canal distensibility

2018 ◽  
Author(s):  
Ssu Chi Chen ◽  
Kaori Futaba ◽  
Wing Wa Leung ◽  
Cherry Wong ◽  
Tony Mak ◽  
...  
Keyword(s):  
Anal Canal ◽  
Imaging Probe ◽  
Functional Lumen Imaging Probe

Su1616 - Functional Lumen Imaging Probe (FLIP) to Perform Biofeedback and Strengthening of the Anal Canal Muscles

2018 ◽  
Vol 154 (6) ◽  
pp. S-549-S-550
Author(s):  
Lori Tuttle ◽  
David C. Kunkel ◽  
Ravinder K. Mittal
Keyword(s):  
Anal Canal ◽  
Imaging Probe ◽  
Functional Lumen Imaging Probe

scholarly journals Loop analysis of the anal sphincter complex in fecal incontinent patients using functional luminal imaging probe

2020 ◽  
Vol 318 (1) ◽  
pp. G66-G76 ◽  
Author(s):  
Ali Zifan ◽  
Ravinder K. Mittal ◽  
David C. Kunkel ◽  
Jessica Swartz ◽  
Garrett Barr ◽  
...  
Keyword(s):  
Fecal Incontinence ◽  
Anal Canal ◽  
Anal Sphincter ◽  
Normal Subjects ◽  
Sphincter Muscle ◽  
Upward Movement ◽  
Loop Analysis ◽  
Imaging Probe ◽  
Functional Luminal Imaging Probe ◽  
The Right

Cardiac loops have been used extensively to study myocardial function. With changes in cardiac pump function, loops are shifted to the right or left. Functional luminal imaging probe (FLIP) recordings allow for loop analysis of the anal sphincter and puborectalis muscle (PRM) function. The goal was to characterize anal sphincter area-pressure/tension loop changes in fecal incontinence (FI) patients. Fourteen healthy subjects and 14 patients with FI were studied. A custom-designed FLIP was placed in the vagina and then in the anal canal, and deflated in 20-ml steps, from 90 to 30 ml. At each volume, subjects performed maximal voluntary squeezes. Area-pressure (AP) and area-tension (AT) loops were generated for each squeeze cycle. Three-dimensional ultrasound imaging of the anal sphincter and PRM were obtained to determine the relationship between anal sphincter muscle damage and loop movements. With the increase in bag volume, AP loops and AT loops shifted to the right and upward in normal subjects (both anal and vaginal). The shift to the right was greater, and the upward movement was less in FI patients. The difference in the location of AP loops and AT loops was statistically significant at volumes of 50 ml to 90 ml ( P < 0.05). A similar pattern was found in the vaginal loops. There is a significant relationship between the damage to the anal sphincter and PRM, and loop location of FI patients. We propose AP and AT loops as novel ways to assess the anal sphincter and PRM function. Such loops can be generated by real-time measurement of pressure and area within the anal canal. NEW & NOTEWORTHY We describe the use of area-pressure (AP) and area-tension (AT)-loop analysis of the anal sphincters and puborectalis muscles in normal subjects and fecal incontinent patients using the functional luminal imaging probe (FLIP). There are differences in the magnitude of the displacement of the loops with increase in the FLIP bag volume between normal subjects and patients with fecal incontinence. The latter group shifts more to the right in AP and AT space.

Distensibility of the anal canal in patients with systemic sclerosis: a study with the functional lumen imaging probe

2012 ◽  
Vol 15 (1) ◽  
pp. e40-e47 ◽  
Author(s):  
L. Fynne ◽  
F. Luft ◽  
H. Gregersen ◽  
S. Buntzen ◽  
L. Lundby ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Anal Canal ◽  
Imaging Probe ◽  
Functional Lumen Imaging Probe

Clinical utility of a functional lumen imaging probe in management of dysphagia following head and neck cancer therapies

Endoscopy ◽  
2017 ◽  
Vol 49 (09) ◽  
pp. 848-854 ◽  
Author(s):  
Peter Wu ◽  
Michal Szczesniak ◽  
Julia Maclean ◽  
Lennart Choo ◽  
Harry Quon ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Diagnostic Accuracy ◽  
Head And Neck ◽  
Neck Cancer ◽  
Characteristic Curve ◽  
Diagnostic Tools ◽  
Cross Sectional ◽  
Imaging Probe ◽  
Functional Lumen Imaging Probe ◽  
Dysphagic Patients

Abstract Background and aims Chemoradiotherapy for head and neck cancer (HNC) with/without laryngectomy commonly causes dysphagia. Pharyngoesophageal junction (PEJ) stricturing is an important contributor. We aimed to validate a functional lumen imaging probe (the EndoFLIP system) as a tool for quantitating pretreatment PEJ distensibility and treatment-related changes in HNC survivors with dysphagia and to evaluate the diagnostic accuracy of EndoFLIP-derived distensibility in detecting PEJ strictures. Methods We studied 34 consecutive HNC survivors with long-term (> 12 months) dysphagia who underwent endoscopic dilation for suspected strictures. Twenty non-dysphagic patients undergoing routine endoscopy served as controls. PEJ distensibility was measured at endoscopy with the EndoFLIP system pre- and post-dilation. PEJ stricture was defined as the presence of a mucosal tear post-dilation. Results PEJ stricture was confirmed in 22/34 HNC patients (65 %). During distension up to 60 mmHg, the mean EndoFLIP-derived narrowest cross-sectional area (nCSA) in HNC patients with strictures, without strictures, and in controls were 58 mm2 (95 % confidence interval [CI] 22 to 118), 195 mm2 (95 %CI 129 to 334), and 227 mm2 (95 %CI 168 to 316), respectively. A cutoff of 114 mm2 for the nCSA at the PEJ had perfect diagnostic accuracy in detecting strictures (area under the receiver operating characteristic curve = 1). In patients with strictures, a single session of dilation increased the nCSA by 29 mm2 (95 %CI 20 to 37; P < 0.001). In patients with no strictures, dilation caused no change in the nCSA (mean difference 13 mm2 [95 %CI −4 to 30]; P = 0.13). Conclusions EndoFLIP is a highly accurate technique for the detection of PEJ strictures. EndoFLIP may complement conventional diagnostic tools in the detection of pharyngeal outflow obstruction.

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