Malignant peripheral nerve sheath tumor of the trigeminal nerve: Clinicopathologic features in a young adult patient

2012 ◽  
pp. n/a-n/a ◽  
Author(s):  
Yoko Nakayama ◽  
Masatoshi Watanabe ◽  
Kenji Suzuki ◽  
Hiroyuki Usuda ◽  
Iwao Emura ◽  
...  
Medicine ◽  
2018 ◽  
Vol 97 (39) ◽  
pp. e12040
Author(s):  
Hyojeong Kim ◽  
Do Young Kim ◽  
Young Mi Seol ◽  
Ja Yoon Ku ◽  
Kyung Un Choi ◽  
...  

Neurosurgery ◽  
2006 ◽  
Vol 59 (2) ◽  
pp. E425-E425 ◽  
Author(s):  
Andreas M. Stark ◽  
Ralf Buhl ◽  
Heinz-Herrmann Hugo ◽  
Thorsten Straube ◽  
H Maximilian Mehdorn

Abstract OBJECTIVE: Clinically significant intratumoral or peritumoral bleeding from trigeminal nerve tumors is very rare. CLINICAL PRESENTATION: We report the case of a 59-year-old man who presented with recurrent subarachnoid hemorrhage from a left trigeminal nerve malignant peripheral nerve sheath tumor. He presented with decreased consciousness, left facial hypesthesia, and left facial weakness. Trigeminal neuralgia was present for 18 months. Cranial computed tomographic and magnetic resonance imaging scans revealed a left parapontine mass with cystic changes and intratumoral bleeding. Furthermore, signs of hemosiderosis of the subarachnoid space were noted. Lumbar puncture revealed fresh bleeding. Angiography detected no aneurysm or other causes of bleeding. The patient became fully alert within hours, the facial weakness improved within a few days. There was no evidence of vasospasm or persisting hydrocephalus. He underwent left-sided suboccipital craniotomy for macroscopically total tumor removal. INTERVENTION: The patient underwent total tumor removal via a left suboccipital approach. Intraoperatively, evidence of recurrent intratumoral bleeding was noted. Histological examination revealed a malignant peripheral nerve sheath tumor (World Health Organization Grade III). Postoperatively, the hypesthesia improved significantly. The patient was transferred to radiotherapy for external beam radiation. CONCLUSIONS: This is the first report regarding a malignant peripheral nerve sheath tumor of the trigeminal nerve that caused clinically significant subarachnoid hemorrhage caused by intratumoral bleeding.


2018 ◽  
Vol 112 ◽  
pp. 221-226 ◽  
Author(s):  
Aijun Liang ◽  
Bin Xi ◽  
Chaoyang Zhou ◽  
Yu Yang ◽  
Jianzhong Zhang ◽  
...  

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Zheng Melissa ◽  
Li Zhonghua ◽  
Mulvey Carolyn L ◽  
Staddon Arthur P ◽  
Kennedy David W ◽  
...  

2000 ◽  
Vol 124 (8) ◽  
pp. 1172-1178 ◽  
Author(s):  
Dmitry Y. Baschinsky ◽  
Janny H. Chen ◽  
Manjunath S. Vadmal ◽  
Joel G. Lucas ◽  
Robert R. Bahnson ◽  
...  

Abstract Objective.—Carcinosarcomas of urinary bladder are rare malignant neoplasms. Seventy-eight cases have been previously described. The histologic composition of these tumors is variable, but diagnosis requires the presence of both epithelial and mesenchymal malignant components. We report 4 additional cases, with an emphasis on unusual histologic features. Methods.—Histologic and immunohistochemical examinations were performed on bladder tumors from 4 patients. Clinicopathologic features of previously reported and current cases were reviewed and summarized. Results.—Four patients (3 men, 1 woman) age 54 to 77 years were found to have polypoid masses in the urinary bladder. In all cases, histologic examination showed biphasic neoplasms with distinct mesenchymal and epithelial components. The morphologic and immunohistochemical characteristics of the tumors varied. One of the cases was remarkable for the presence of liposarcoma, malignant peripheral nerve sheath tumor, and micropapillary urothelial carcinoma. Two of the patients died 2 years after diagnosis, which is consistent with the previously reported aggressive nature of urinary bladder carcinosarcomas. Conclusions.—Carcinosarcomas of the urinary bladder are rare, aggressive malignant neoplasms. To our knowledge, a liposarcomatous component has been reported in only 1 case previously, and components of micropapillary urothelial carcinoma and malignant peripheral nerve sheath tumor have not been reported previously in carcinosarcomas of the urinary bladder. Because of the aggressive biologic behavior of these tumors, they should be identified promptly and treated appropriately.


2016 ◽  
Vol 78 (5) ◽  
pp. 516-521
Author(s):  
Fumihisa SAWADA ◽  
Eiichi MAKINO ◽  
Takenobu YAMAMOTO ◽  
Ryo TANAKA ◽  
Yutaka FUJIWARA ◽  
...  

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