scholarly journals Perineural Invasion through the Maxillary Division of the Right Trigeminal Nerve in a Rare Case of Nasolabial Malignant Peripheral Nerve Sheath Tumor

2008 ◽  
Vol 29 (2) ◽  
pp. 396-397 ◽  
Author(s):  
C. Sempere-Ortega ◽  
J. Martinez-San-Millan
Keyword(s):  
Peripheral Nerve ◽  
Trigeminal Nerve ◽  
Rare Case ◽  
Perineural Invasion ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
The Right

Malignant peripheral nerve sheath tumor (MPNST) arising from angiosarcoma: a rare case report

2019 ◽  
Vol 23 (1) ◽  
pp. 109-112
Author(s):  
Maria Lazaridou ◽  
Eleni Bourlidou ◽  
Margarita Vafeiadou ◽  
Yiannis Papadiochos ◽  
Nikolaos Barbetakis ◽  
...  
Keyword(s):  
Case Report ◽  
Peripheral Nerve ◽  
Rare Case ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Rare Case Report

Pleomorphic Corneal Sarcoma Resembling Malignant Peripheral Nerve Sheath Tumor in a Horse

2009 ◽  
Vol 46 (3) ◽  
pp. 444-448 ◽  
Author(s):  
E. C. Kappe ◽  
K. KÖHLER ◽  
I. v. Felbert ◽  
J. P. Teifke ◽  
J. TÓTH ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Domestic Animals ◽  
Bovine Papillomavirus ◽  
Nerve Sheath Tumor ◽  
Human Beings ◽  
Immunohistochemical Examination ◽  
Peripheral Nerve Sheath Tumor ◽  
Mesenchymal Neoplasms ◽  
Nerve Sheath ◽  
The Right

A 14-year-old Haflinger gelding presented with a protruding mass involving the cornea of the right eye. The mass was resected and submitted for histopathologic and immunohistochemical examination. The preliminary diagnosis was corneal sarcoma, most likely fibrosarcoma. The immunohistochemical results confirmed the mesenchymal origin of the neoplastic cells, which were most consistent with a malignant peripheral nerve sheath tumor. Corneal mesenchymal neoplasms are extremely uncommon tumors in human beings and domestic animals. The cause for this tumor was not determined; infection with bovine papillomavirus was not detected.

scholarly journals Malignant peripheral nerve sheath tumor of the distal phalanx of the fifth toe: a case report

2014 ◽  
Vol 3 (1) ◽  
pp. 204798161351603 ◽  
Author(s):  
Yuki Iwama ◽  
Makoto Kunisada ◽  
Hajimu Goto ◽  
Yoshiharu Ohno ◽  
Junji Yamashita ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Distal Phalanx ◽  
Nerve Sheath Tumor ◽  
Resonance Imaging ◽  
Peripheral Nerve Sheath Tumor ◽  
Histological Features ◽  
Nerve Sheath ◽  
Subcutaneous Tissues ◽  
Fifth Toe ◽  
The Right

Malignant peripheral nerve sheath tumor (MPNST) involving bone is rare. We report a case of MPNST of the fifth toe. The lesion was located in the distal phalanx of the right fifth toe and extended into surrounding subcutaneous tissues. Findings on magnetic resonance imaging and histological features of the case are described and the literature is briefly reviewed.

scholarly journals First documented case of intracranial falcine malignant peripheral nerve sheath tumor: illustrative case

2021 ◽  
Vol 2 (6) ◽  
Author(s):  
Renato J. Galzio ◽  
Mattia Del Maestro ◽  
Diamantoula Pagkou ◽  
Massimo Caulo ◽  
Sofia Asioli ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Cranial Nerves ◽  
Illustrative Case ◽  
Nerve Sheath Tumor ◽  
Falx Cerebri ◽  
Peripheral Nerve Sheath Tumor ◽  
Documented Case ◽  
Nerve Sheath ◽  
First Case ◽  
The Right

BACKGROUND The authors reported the first documented case of intracranial extraaxial nonneurofibromatosis type 1–related nontriton malignant peripheral nerve sheath tumor (MPNST) originating from the falx cerebri. OBSERVATIONS A 34-year-old man with headache, short-term memory deficit, postural instability, and blurred vision presented with a large heterogenous contrast-enhanced intraventricular cystic lesion originating from the free margin of the falx cerebri. The patient received surgery using the right posterior interhemispheric approach. Gross total resection was performed, and the inferior border of the falx cerebri was resected. The postoperative course was uneventful. Histological examination revealed hypercellular foci of neoplastic spindle cells with hyperchromatic and wavy nuclei. Hence, a diagnosis of MPNST was made based on concomitant immunochemistry findings, including mouse double minute 2 homolog focal positivity and geographic loss of H3K27me3. The patient received adjuvant radiotherapy, and recurrence was not observed. LESSONS Intracranial MPNSTs are extremely rare tumors, typically originating from the cranial nerves in the posterior cranial fossa. An even rarer variant of these tumors, referred to as malignant intracerebral nerve sheath tumors, may directly arise from the brain parenchyma. The authors reported the first case of an intracranial MPNST originating from the dura mater of the falx cerebri, acting as an extraaxial lesion with prevalent expansion in the right ventricle.

scholarly journals Malignant Peripheral Nerve Sheath Tumor of the Inguinum and Angiosarcoma of the Scalp in a Child with Neurofibromatosis Type 1

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Marija Milković Periša ◽  
Tihana Džombeta ◽  
Jasminka Stepan Giljević ◽  
Božo Krušlin
Keyword(s):  
Peripheral Nerve ◽  
Neurofibromatosis Type 1 ◽  
Malignant Tumors ◽  
Young Patients ◽  
Neurofibromatosis Type ◽  
Nerve Sheath Tumor ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
The Right

Benign and malignant tumors are common in the setting of neurofibromatosis type 1 (NF1). Malignant peripheral nerve sheath tumor (MPNST) and angiosarcoma are rare tumors in children and adolescents and mostly occur in young patients in relation to NF1. Both histological types can be present in the same tumor mass in patients with NF1. We present a case of 12.5-year-old girl with NF1 who first presented with MPNST of the right inguinal region and 1.5 years later with unrelated angiosarcoma of the scalp.

Chronic Recurrent Subarachnoid Hemorrhage from a Trigeminal Nerve Malignant Peripheral Nerve Sheath Tumor

Neurosurgery ◽  
2006 ◽  
Vol 59 (2) ◽  
pp. E425-E425 ◽  
Author(s):  
Andreas M. Stark ◽  
Ralf Buhl ◽  
Heinz-Herrmann Hugo ◽  
Thorsten Straube ◽  
H Maximilian Mehdorn
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Peripheral Nerve ◽  
Trigeminal Nerve ◽  
Nerve Sheath Tumor ◽  
Facial Weakness ◽  
Peripheral Nerve Sheath Tumor ◽  
Nerve Sheath ◽  
Clinically Significant ◽  
Total Tumor Removal ◽  
Intratumoral Bleeding

Abstract OBJECTIVE: Clinically significant intratumoral or peritumoral bleeding from trigeminal nerve tumors is very rare. CLINICAL PRESENTATION: We report the case of a 59-year-old man who presented with recurrent subarachnoid hemorrhage from a left trigeminal nerve malignant peripheral nerve sheath tumor. He presented with decreased consciousness, left facial hypesthesia, and left facial weakness. Trigeminal neuralgia was present for 18 months. Cranial computed tomographic and magnetic resonance imaging scans revealed a left parapontine mass with cystic changes and intratumoral bleeding. Furthermore, signs of hemosiderosis of the subarachnoid space were noted. Lumbar puncture revealed fresh bleeding. Angiography detected no aneurysm or other causes of bleeding. The patient became fully alert within hours, the facial weakness improved within a few days. There was no evidence of vasospasm or persisting hydrocephalus. He underwent left-sided suboccipital craniotomy for macroscopically total tumor removal. INTERVENTION: The patient underwent total tumor removal via a left suboccipital approach. Intraoperatively, evidence of recurrent intratumoral bleeding was noted. Histological examination revealed a malignant peripheral nerve sheath tumor (World Health Organization Grade III). Postoperatively, the hypesthesia improved significantly. The patient was transferred to radiotherapy for external beam radiation. CONCLUSIONS: This is the first report regarding a malignant peripheral nerve sheath tumor of the trigeminal nerve that caused clinically significant subarachnoid hemorrhage caused by intratumoral bleeding.

scholarly journals RT-5 Boron Neutron Capture Therapy has extended progression-free survival about recurrent malignant peripheral nerve sheath tumor - A case report

2021 ◽  
Vol 3 (Supplement_6) ◽  
pp. vi15-vi15
Author(s):  
Yuko Watanabe ◽  
Hiroshi Igaki ◽  
Ayumu Arakawa ◽  
Shunsuke Yanagisawa ◽  
Masamichi Takahashi ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Neutron Capture ◽  
Progression Free Survival ◽  
Neutron Capture Therapy ◽  
Nerve Sheath Tumor ◽  
Free Survival ◽  
Peripheral Nerve Sheath Tumor ◽  
Boron Neutron Capture ◽  
Nerve Sheath ◽  
The Right

Abstract Introduction: Recurrent malignant peripheral nerve sheath tumor (MPNST) is intractable. Boron neutron capture therapy (BNCT) is a treatment using tumor-selective particle radiation, and is indicated for medical treatment for head and neck cancer, and also used for malignant glioma and malignant meningioma.<Case>20-year-old woman who has MPNST that extends from the subcutaneous tissue of the right neck to the posterior fossa. <Medical History>Chemotherapy and local irradiation(50.4Gy/28fr) for primary embryonal rhabdomyosarcoma of the right ear canal at the age six.<Current medical history>Right cervical tumor developed at 17-year-old, some chemotherapy regimens and tumor resections were performed as recurrence of rhabdomyosarcoma at the previous hospital. After she was diagnosed with MPNST in the pathology consultation at our hospital, she was irradiated with heavy ion beam 70.8Gy(RBE)/16fr and received additional chemotherapies at our department, but her tumor was refractory. Although BNCT for MPNST is not covered by health insurance in Japan, she wanted to try to be treated for BNCT. After confirming boron accumulation in the tumor (SUVmax 4.28) by FBPA-PET, tumor growth and hydrocephalus occurred while waiting for travel to Taiwan due to the spread of COVID-19 infection. She was performed tumor resection(NTR) and irradiated with SRS 20Gy/fr for the residual lesion, but tumor had a rapid recurrence from the margin of the excision cavity. Finally, she could travel about 3 months after the operation and underwent BNCT, that used neutrons and 10B-boronophenylalanine from the Tsinghua University research reactor in Taiwan. No serious adverse events including cerebral edema were observed, and dramatic tumor shrinkage was maintained after treatment. FBPA-PET of 3 months later showed accumulation in the part of the margin of the cavity, the recurrence was observed on MRI after 3 and a half months. Discussion: BNCT for refractory/recurrent MPNST showed acceptable safety and was able to prolong progression-free survival.

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