Effects of Estrogen on Vulvovaginal Candidosis

Mycoses ◽  
2021 ◽  
Author(s):  
Yufei He ◽  
Ruoyu Tang ◽  
Jie Deng ◽  
Tongkai Cai ◽  
Ping He ◽  
...  
2021 ◽  
Vol 7 (3) ◽  
pp. 233
Author(s):  
Philipp Foessleitner ◽  
Herbert Kiss ◽  
Julia Deinsberger ◽  
Julia Ott ◽  
Lorenz Zierhut ◽  
...  

Pregnant women have an increased risk of vulvovaginal candidosis. Recurrent candidosis is under debate as a contributor to preterm birth, and vertical transmission may cause diaper dermatitis and oral thrush in the newborn. Apart from cultural methods, the gold standard for diagnosing candidosis is Gram staining, which is time-consuming and requires laboratory facilities. The objective of this prospective study was to validate a point-of-care vaginal yeast detection assay (SavvyCheckÔ Vaginal Yeast Test) and to evaluate it in asymptomatic pregnant women. We enrolled 200 participants, 100 of whom had vulvovaginal candidosis according to Gram stain (study group) and 100 were healthy pregnant controls (control group). Of these, 22 participants (11%) had invalid test results. The point-of-care test of the remaining 85 and 93 study participants in the study and control groups, respectively, showed a sensitivity of 94.1%, specificity of 98.9%, positive predictive value of 90.3%, and negative predictive value of 99.4% when compared with Gram stain. In conclusion, we found a high correlation between the SavvyCheckÔ Vaginal Yeast Test and Gram-stained smears during pregnancy. This suggests a potential role of this point-of-care test as a screening tool for asymptomatic pregnant women in early gestation.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Eline F. M. Oerlemans ◽  
Gert Bellen ◽  
Ingmar Claes ◽  
Tim Henkens ◽  
Camille Nina Allonsius ◽  
...  

Author(s):  
Birgitta Zdolsek ◽  
Dan Hellberg ◽  
Gunnar Fróman ◽  
Staffan Nilsson ◽  
Per-Anders Mårdh

Mycoses ◽  
2002 ◽  
Vol 45 (S2) ◽  
pp. 44-44
Author(s):  
N. Novikova ◽  
E. Stukalova ◽  
D. Slonova ◽  
P. A. Mårdh

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