IV. MODEL SIMULATIONS TESTING THE REAL-TIME STABILITY HYPOTHESIS OF DEVELOPMENTAL CHANGES IN VISUAL WORKING MEMORY

2016 ◽  
Vol 81 (3) ◽  
pp. 82-108
Author(s):  
Vanessa R. Simmering
2020 ◽  
Author(s):  
Alireza Ebrahim ◽  
Karl DeVore ◽  
Tim Fischer

Abstract Background An accelerated stability model based on the Arrhenius Equation can be used to estimate stability of diagnostic reagents. Here we review 3 examples in which the model does not accurately predict the stability of diagnostic reagents. Methods We prepared several pilot lots of quality controls materials containing fructosamine, BNP, and HbA1c in human whole blood and serum matrices and performed accelerated stability studies at increased temperatures (5 °C to 35 °C) and real-time stability studies at the recommended storage temperature (-10 °C to -20 °C) for several analytes in quality control materials. Results We observed that the stability predictions obtained from the accelerated stability studies were longer in 2 instances and much shorter in another than those observed from the real-time stability studies. Conclusions Due to discrepancies between the stability results from accelerated stability studies and those from the real-time stability studies, we stress the need for caution when reagent manufacturers use the Arrhenius model and recommend that the technical groups and committees assigned to revise CLSI and ISO stability documents highlight the limitations of the accelerated stability model and include more guidance and direction on how and when to use the accelerated stability model.


2020 ◽  
Vol 2020 (101) ◽  
pp. 1-32
Author(s):  
Alessandro Barbarino ◽  
◽  
Travis J. Berge ◽  
Han Chen ◽  
Andrea Stella ◽  
...  

Output gaps that are estimated in real time can differ substantially from those estimated after the fact. We aim to understand the real-time instability of output gap estimates by comparing a suite of reduced-form models. We propose a new statistical decomposition and find that including a Okun’s law relationship improves real-time stability by alleviating the end-point problem. Models that include the unemployment rate also produce output gaps with relevant economic content. However, we find that no model of the output gap is clearly superior to the others along each metric we consider.


2015 ◽  
Vol 41 (11) ◽  
pp. 1769-1776 ◽  
Author(s):  
Dalia Mohamed ◽  
Ibrahim Elsayed ◽  
Aly Fahmy Mohamed ◽  
Soad Ali Yehia

2013 ◽  
Vol 28 (4) ◽  
pp. 60-66 ◽  
Author(s):  
Zhao Yang Dong ◽  
Yan Xu ◽  
Pei Zhang ◽  
Kit Po Wong

Author(s):  
Farzad Ferdowsi ◽  
Hesan Vahedi ◽  
Ali Jafarian Abianeh ◽  
Chris S. Edrington ◽  
Touria Elmezyani

Author(s):  
Mladen Kezunovic ◽  
Sakis Meliopoulos ◽  
Vaithianathan Venkatasubramanian ◽  
Vijay Vittal

2020 ◽  
Author(s):  
Timothy F. Brady ◽  
Viola S. Störmer ◽  
Anna Shafer-Skelton ◽  
Jamal Rodgers Williams ◽  
Angus F. Chapman ◽  
...  

Both visual attention and visual working memory tend to be studied with very simple stimuli and low-level paradigms, designed to allow us to understand the representations and processes in detail, or with fully realistic stimuli that make such precise understanding difficult but are more representative of the real world. In this chapter we argue for an intermediate approach in which visual attention and visual working memory are studied by scaling up from the simplest settings to more complex settings that capture some aspects of the complexity of the real-world, while still remaining in the realm of well-controlled stimuli and well-understood tasks. We believe this approach, which we have been taking in our labs, will allow a more generalizable set of knowledge about visual attention and visual working memory while maintaining the rigor and control that is typical of vision science and psychophysics studies.


BioTechniques ◽  
2014 ◽  
Vol 57 (3) ◽  
pp. 151-155 ◽  
Author(s):  
Markus Rombach ◽  
Dominique Kosse ◽  
Bernd Faltin ◽  
Simon Wadle ◽  
Günter Roth ◽  
...  

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