scholarly journals Polyphosphate is involved in cell cycle progression and genomic stability inSaccharomyces cerevisiae

2016 ◽  
Vol 101 (3) ◽  
pp. 367-380 ◽  
Author(s):  
Samuel Bru ◽  
Joan Marc Martínez-Laínez ◽  
Sara Hernández-Ortega ◽  
Eva Quandt ◽  
Javier Torres-Torronteras ◽  
...  
2018 ◽  
Vol 46 (5) ◽  
pp. 2459-2478 ◽  
Author(s):  
David Dilworth ◽  
Geoff Gudavicius ◽  
Xiaoxue Xu ◽  
Andrew K J Boyce ◽  
Connor O’Sullivan ◽  
...  

Cell Reports ◽  
2016 ◽  
Vol 15 (4) ◽  
pp. 724-734 ◽  
Author(s):  
Teresa L.F. Ho ◽  
Guillaume Guilbaud ◽  
J. Julian Blow ◽  
Julian E. Sale ◽  
Christine J. Watson

Cell Cycle ◽  
2004 ◽  
Vol 3 (10) ◽  
pp. 1296-1304 ◽  
Author(s):  
Khe Guan Sim ◽  
Zhijiang Zang ◽  
Christopher Maolin Yang ◽  
Joseph V. Bonventre ◽  
Stephen I-Hong Hsu

2000 ◽  
Vol 104 (12) ◽  
pp. 1439-1448 ◽  
Author(s):  
Michelle A. Hughes ◽  
Deborah A. Barnett ◽  
Zainon Mohd-Noor ◽  
Susan L. Whittaker ◽  
John H. Doonan ◽  
...  

2009 ◽  
Vol 30 (1) ◽  
pp. 22-32 ◽  
Author(s):  
Cheen Fei Chin ◽  
Foong May Yeong

ABSTRACT Maintenance of genomic stability is needed for cells to survive many rounds of division throughout their lifetime. Key to the proper inheritance of intact genome is the tight temporal and spatial coordination of cell cycle events. Moreover, checkpoints are present that function to monitor the proper execution of cell cycle processes. For instance, the DNA damage and spindle assembly checkpoints ensure genomic integrity by delaying cell cycle progression in the presence of DNA or spindle damage, respectively. A checkpoint that has recently been gaining attention is the antephase checkpoint that acts to prevent cells from entering mitosis in response to a range of stress agents. We review here what is known about the pathway that monitors the status of the cells at the brink of entry into mitosis when cells are exposed to insults that threaten the proper inheritance of chromosomes. We highlight issues which are unresolved in terms of our understanding of the antephase checkpoint and provide some perspectives on what lies ahead in the understanding of how the checkpoint functions.


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