Risk of gallbladder cancer in patients with primary sclerosing cholangitis and radiographically detected gallbladder polyps

2019 ◽  
Vol 40 (2) ◽  
pp. 382-392 ◽  
Author(s):  
Liselot W. Erp ◽  
Morven Cunningham ◽  
Manasa Narasimman ◽  
Hamideh Ale Ali ◽  
Kartik Jhaveri ◽  
...  
Keyword(s):  
Gallbladder Cancer ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Gallbladder Polyps

Cholestatic Liver Injury: Care of Patients With Primary Biliary Cholangitis or Primary Sclerosing Cholangitis

2016 ◽  
Vol 27 (4) ◽  
pp. 441-452 ◽  
Author(s):  
Laurie Larson ◽  
Michelle James ◽  
Andrea Gossard
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Disease Recurrence ◽  
Outpatient Setting ◽  
Primary Biliary Cholangitis ◽  
Malignant Neoplasms ◽  
Cholestatic Liver Disease ◽  
Gallbladder Polyps ◽  
Increased Risk ◽  
Common Causes

The most common causes of chronic cholestatic liver disease are primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). Both disease processes are characterized by a destruction of intrahepatic and/or extrahepatic biliary ducts. The etiology is not entirely clear; however, there is an underlying autoimmune component contributing to both disease processes. Although PBC and PSC are often diagnosed and managed in the outpatient setting, in some instances, a patient may have jaundice, fatigue, and pruritus requiring evaluation and determination of the cholestatic cause. Patients with PSC should be monitored for evidence of cholangiocarcinoma, colon cancer, and gallbladder polyps as they are at an increased risk of malignant neoplasms. Liver transplant has the potential for improving quality of life, although disease recurrence is a risk.

In primary sclerosing cholangitis, gallbladder polyps are frequently malignant

2002 ◽  
Vol 97 (5) ◽  
pp. 1138-1142 ◽  
Author(s):  
Daniel C. Buckles ◽  
Keith D. Lindor ◽  
Nicholas F. LaRusso ◽  
Lydia M. Petrovic ◽  
Gregory J. Gores
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Gallbladder Polyps

Patients with primary sclerosing cholangitis and gallbladder polyps should undergo cholecystectomy

2001 ◽  
Vol 120 (5) ◽  
pp. A75
Author(s):  
Daniel C. Buckles ◽  
Keith D. Lindor ◽  
Nicholas F. Larusso ◽  
Gregory J. Gores
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Gallbladder Polyps

scholarly journals Is primary sclerosing cholangitis-related gallbladder cancer associated with worse survival? Results from the U.S. extrahepatic biliary malignancy consortium

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S68-S69
Author(s):  
V.R. Rendell ◽  
A.V. Fisher ◽  
A.I. Salem ◽  
A.A. Rahnemai-Azar ◽  
C.G. Ethun ◽  
...  
Keyword(s):  
Gallbladder Cancer ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Biliary Malignancy ◽  
The U.S

373 Long-Term Outcome of Gallbladder Polyps in Patients With Primary Sclerosing Cholangitis

2010 ◽  
Vol 138 (5) ◽  
pp. S-787
Author(s):  
Sombat Treeprasertsuk ◽  
Emmanouil Sinakos ◽  
Jill C. Keach ◽  
Keith D. Lindor
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Gallbladder Polyps
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