Influence of Escherichia coli endotoxemia on danofloxacin pharmacokinetics in broilers following single oral administration

2021 ◽  
Author(s):  
Han Wang ◽  
Fang Yang ◽  
Zhe‐Wen Song ◽  
Hao‐Tian Shao ◽  
Mei Zhang ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Oral Administration ◽  
Single Oral Administration

Josamycin concentrations in radicular cysts following a single oral administration

1993 ◽  
Vol 24 (1) ◽  
pp. 143-145 ◽  
Author(s):  
Yoshiaki Akimoto ◽  
Yoshiko Mochizuki ◽  
Akio Uda ◽  
Hiroaki Omata ◽  
Sumio Saito ◽  
...  
Keyword(s):  
Oral Administration ◽  
Single Oral Administration

Bacteriophages reduce Escherichia coli O157:H7 levels in experimentally inoculated sheep

2009 ◽  
Vol 89 (2) ◽  
pp. 285-293 ◽  
Author(s):  
S J Bach ◽  
R P Johnson ◽  
K. Stanford ◽  
T A McAllister
Keyword(s):  
Escherichia Coli ◽  
Oral Administration ◽  
Coliform Bacteria ◽  
Escherichia Coli O157 ◽  
Fecal Shedding ◽  
Total Coliforms ◽  
E Coli ◽  
Oral Inoculation ◽  
Experimental Treatments ◽  
And Control

Bacteriophage biocontrol has potential as a means of mitigating the prevalence of Escherichia coli O157:H7 in ruminants. The efficacy of oral administration of bacteriophages for reducing fecal shedding of E. coli O157:H7 by sheep was evaluated using 20 Canadian Arcott rams (50.0 ± 3.0) housed in four rooms (n = 5) in a contained facility. The rams had ad libitum access to drinking water and a pelleted barley-based total mixed ration, delivered once daily. Experimental treatments consisted of administration of E. coli O157:H7 (O157), E. coli O157:H7+bacteriophages (O157+phage), bacteriophages (phage), and control (CON). Oral inoculation of the rams with 109 CFU of a mixture of four nalidixic acid-resistant strains of E. coli O157:H7 was performed on day 0. A mixture of 1010 PFU of bacteriophages P5, P8 and P11 was administered on days -2, -1, 0, 6 and 7. Fecal samples collected on 14 occasions over 21 d were analyzed for E. coli O157:H7, total E. coli, total coliforms and bacteriophages. Sheep in treatment O157+phage shed fewer (P < 0.05) E. coli O157:H7 than did sheep in treatment O157. Populations of total coliforms and total E. coli were similar (P < 0.05) among treatments, implying that bacteriophage lysis of non-target E. coli and coliform bacteria in the gastrointestinal tract did not occur. Bacteriophage numbers declined rapidly over 21 d, which likely reduced the chance of collision between bacteria and bacteriophage. Oral administration of bacteriophages reduced shedding of E. coli O157:H7 by sheep, but a delivery system that would protect bacteriophages during passage through the intestine may increase the effectiveness of this strategy as well as allow phage to be administered in the feed.Key words: Escherichia coli O157:H7, bacteriophage, sheep, environment, coliforms

Pharmacokinetics and tolerance of the hypolipidaemic RP 54275 following single oral administration to male volunteers

1990 ◽  
Vol 183 (5) ◽  
pp. 1846-1847
Author(s):  
C.D. Evans ◽  
G.D. Jones ◽  
V. Facchini ◽  
J. McEwen ◽  
Y. Yeang
Keyword(s):  
Oral Administration ◽  
Male Volunteers ◽  
Single Oral Administration

Pharmacokinetics of a single oral administration of cefalexin in mares and foals

2011 ◽  
Vol 168 (16) ◽  
pp. 431-431
Author(s):  
G. J. B. Ladaga ◽  
F. P. Lezica ◽  
A. M. Barboni ◽  
J. A. Picos ◽  
G. A. de Erausquin
Keyword(s):  
Oral Administration ◽  
Single Oral Administration

Bioequivalence of Two Tablet Formulations of Atenolol after Single Oral Administration in Healthy Volunteers

2011 ◽  
Vol 50 (03) ◽  
pp. 243-247
Author(s):  
Ioannis Niopas ◽  
Athanasios Daftsios ◽  
Ioannis Xanthakis ◽  
Nicolaos Nikolaidis ◽  
Samuel Njau
Keyword(s):  
Oral Administration ◽  
Healthy Volunteers ◽  
Single Oral Administration ◽  
Tablet Formulations
Sign in / Sign up

Export Citation Format

Share Document